Financial Metrics

APLS Apellis Pharmaceuticals, Inc.

Range: 2016-01-01 to 2026-04-29

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Financial Statements

Grouped by statement

Income Statement

Metrics: 6

Revenue

Q: 16 | A: 6

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2020-06-30	0.0	—	USD	10-Q	2021-08-09
Quarterly	2020-09-30	646000.0	—	USD	10-Q	2021-11-08
Quarterly	2021-06-30	623000.0	-3.6%	USD	10-Q	2022-08-08
Quarterly	2021-09-30	5650000.0	+806.9%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	14381000.0	+154.5%	USD	10-Q	2023-05-04
Quarterly	2022-06-30	16322000.0	+13.5%	USD	10-Q	2023-07-31
Quarterly	2022-09-30	22056000.0	+35.1%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	44846000.0	+103.3%	USD	10-Q	2024-05-07
Quarterly	2023-06-30	94969000.0	+111.8%	USD	10-Q	2024-08-01
Quarterly	2023-09-30	110399000.0	+16.2%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	172325000.0	+56.1%	USD	10-Q	2025-05-07
Quarterly	2024-06-30	199685000.0	+15.9%	USD	10-Q	2025-07-31
Quarterly	2024-09-30	196830000.0	-1.4%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	166797000.0	-15.3%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	178494000.0	+7.0%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	458578000.0	+156.9%	USD	10-Q	2025-10-30
Annual	2020-12-31	250646000.0	—	USD	10-K	2023-02-21
Annual	2021-12-31	66563000.0	-73.4%	USD	10-K/A	2024-02-29
Annual	2022-12-31	75422000.0	+13.3%	USD	10-K	2025-02-28
Annual	2023-12-31	396591000.0	+425.8%	USD	10-K	2026-02-24
Annual	2024-12-31	781367000.0	+97.0%	USD	10-K	2026-02-24
Annual	2025-12-31	1003782000.0	+28.5%	USD	10-K	2026-02-24

Gross Profit

Q: 0 | A: 0

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed

Operating Income

Q: 28 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-09-30	-7234204.0	—	USD	10-Q	2017-12-20
Quarterly	2017-03-31	-9052493.0	-25.1%	USD	10-Q	2018-04-30
Quarterly	2017-06-30	-12132403.0	-34.0%	USD	10-Q	2018-07-31
Quarterly	2017-09-30	-11589319.0	+4.5%	USD	10-Q	2018-11-13
Quarterly	2018-03-31	-21438145.0	-85.0%	USD	10-Q	2019-05-07
Quarterly	2018-06-30	-33485442.0	-56.2%	USD	10-Q	2019-07-31
Quarterly	2018-09-30	-35804581.0	-6.9%	USD	10-Q	2019-11-05
Quarterly	2019-03-31	-48651000.0	-35.9%	USD	10-Q	2020-04-29
Quarterly	2019-06-30	-63476000.0	-30.5%	USD	10-Q	2020-07-30
Quarterly	2019-09-30	-69948000.0	-10.2%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	-98786000.0	-41.2%	USD	10-Q	2021-04-28
Quarterly	2020-06-30	-115508000.0	-16.9%	USD	10-Q	2021-08-09
Quarterly	2020-09-30	-129552000.0	-12.2%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	-124591000.0	+3.8%	USD	10-Q	2022-05-04
Quarterly	2021-06-30	-194287000.0	-55.9%	USD	10-Q	2022-08-08
Quarterly	2021-09-30	-127995000.0	+34.1%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	-128998000.0	-0.8%	USD	10-Q	2023-05-04
Quarterly	2022-06-30	-148624000.0	-15.2%	USD	10-Q	2023-07-31
Quarterly	2022-09-30	-152938000.0	-2.9%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	-175083000.0	-14.5%	USD	10-Q	2024-05-07
Quarterly	2023-06-30	-120441000.0	+31.2%	USD	10-Q	2024-08-01
Quarterly	2023-09-30	-137080000.0	-13.8%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	-62090000.0	+54.7%	USD	10-Q	2025-05-07
Quarterly	2024-06-30	-29443000.0	+52.6%	USD	10-Q	2025-07-31
Quarterly	2024-09-30	-47280000.0	-60.6%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	-83328000.0	-76.2%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	-33286000.0	+60.1%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	223183000.0	+770.5%	USD	10-Q	2025-10-30
Annual	2016-12-31	-27282342.0	—	USD	10-K	2019-02-26
Annual	2017-12-31	-50767029.0	-86.1%	USD	10-K	2020-02-27
Annual	2018-12-31	-127925000.0	-152.0%	USD	10-K	2021-02-25
Annual	2019-12-31	-288015000.0	-125.1%	USD	10-K	2022-02-28
Annual	2020-12-31	-213726000.0	+25.8%	USD	10-K	2023-02-21
Annual	2021-12-31	-536277000.0	-150.9%	USD	10-K/A	2024-02-29
Annual	2022-12-31	-594613000.0	-10.9%	USD	10-K	2025-02-28
Annual	2023-12-31	-517121000.0	+13.0%	USD	10-K	2026-02-24
Annual	2024-12-31	-164979000.0	+68.1%	USD	10-K	2026-02-24
Annual	2025-12-31	55427000.0	+133.6%	USD	10-K	2026-02-24

Net Income

Q: 28 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-09-30	-7210591.0	—	USD	10-Q	2017-12-20
Quarterly	2017-03-31	-9050773.0	-25.5%	USD	10-Q	2018-04-30
Quarterly	2017-06-30	-12126152.0	-34.0%	USD	10-Q	2018-07-31
Quarterly	2017-09-30	-11573273.0	+4.6%	USD	10-Q	2018-11-13
Quarterly	2018-03-31	-21736304.0	-87.8%	USD	10-Q	2019-11-05
Quarterly	2018-06-30	-33334301.0	-53.4%	USD	10-Q	2019-11-05
Quarterly	2018-09-30	-90616529.0	-171.8%	USD	10-Q	2019-11-05
Quarterly	2019-03-31	-50574000.0	+44.2%	USD	10-Q	2020-11-02
Quarterly	2019-06-30	-71090000.0	-40.6%	USD	10-Q	2020-11-02
Quarterly	2019-09-30	-191489000.0	-169.4%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	-168822000.0	+11.8%	USD	10-Q	2021-11-08
Quarterly	2020-06-30	-118617000.0	+29.7%	USD	10-Q	2021-11-08
Quarterly	2020-09-30	-423139000.0	-256.7%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	-183659000.0	+56.6%	USD	10-Q	2022-11-07
Quarterly	2021-06-30	-219191000.0	-19.3%	USD	10-Q	2022-11-07
Quarterly	2021-09-30	-598421000.0	-173.0%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	-138935000.0	+76.8%	USD	10-Q	2023-11-01
Quarterly	2022-06-30	-155977000.0	-12.3%	USD	10-Q	2023-11-01
Quarterly	2022-09-30	-486181000.0	-211.7%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	-177778000.0	+63.4%	USD	10-Q	2024-11-05
Quarterly	2023-06-30	-122037000.0	+31.4%	USD	10-Q	2024-11-05
Quarterly	2023-09-30	-440052000.0	-260.6%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	-66423000.0	+84.9%	USD	10-Q	2025-10-30
Quarterly	2024-06-30	-37657000.0	+43.3%	USD	10-Q	2025-10-30
Quarterly	2024-09-30	-161525000.0	-328.9%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	-92225000.0	+42.9%	USD	10-Q	2025-10-30
Quarterly	2025-06-30	-42151000.0	+54.3%	USD	10-Q	2025-10-30
Quarterly	2025-09-30	81339000.0	+293.0%	USD	10-Q	2025-10-30
Annual	2016-12-31	-27124637.0	—	USD	10-K	2019-02-26
Annual	2017-12-31	-51006094.0	-88.0%	USD	10-K	2020-02-27
Annual	2018-12-31	-127502000.0	-150.0%	USD	10-K	2021-02-25
Annual	2019-12-31	-304707000.0	-139.0%	USD	10-K	2022-02-28
Annual	2020-12-31	-344874000.0	-13.2%	USD	10-K	2023-02-21
Annual	2021-12-31	-746354000.0	-116.4%	USD	10-K/A	2024-02-29
Annual	2022-12-31	-652172000.0	+12.6%	USD	10-K	2025-02-28
Annual	2023-12-31	-528628000.0	+18.9%	USD	10-K	2026-02-24
Annual	2024-12-31	-197878000.0	+62.6%	USD	10-K	2026-02-24
Annual	2025-12-31	22388000.0	+111.3%	USD	10-K	2026-02-24

EPS Basic

Q: 14 | A: 6

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2021-06-30	-2.72	—	USD/shares	10-Q	2022-08-08
Quarterly	2021-09-30	-2.28	+16.2%	USD/shares	10-Q	2022-11-07
Quarterly	2022-03-31	-1.42	+37.7%	USD/shares	10-Q	2023-05-04
Quarterly	2022-06-30	-1.46	-2.8%	USD/shares	10-Q	2023-07-31
Quarterly	2022-09-30	-1.75	-19.9%	USD/shares	10-Q	2023-11-01
Quarterly	2023-03-31	-1.56	+10.9%	USD/shares	10-Q	2024-05-07
Quarterly	2023-06-30	-1.02	+34.6%	USD/shares	10-Q	2024-08-01
Quarterly	2023-09-30	-1.17	-14.7%	USD/shares	10-Q	2024-11-05
Quarterly	2024-03-31	-0.54	+53.8%	USD/shares	10-Q	2025-05-07
Quarterly	2024-06-30	-0.3	+44.4%	USD/shares	10-Q	2025-07-31
Quarterly	2024-09-30	-0.46	-53.3%	USD/shares	10-Q	2025-10-30
Quarterly	2025-03-31	-0.74	-60.9%	USD/shares	10-Q	2025-05-07
Quarterly	2025-06-30	-0.33	+55.4%	USD/shares	10-Q	2025-07-31
Quarterly	2025-09-30	1.71	+618.2%	USD/shares	10-Q	2025-10-30
Annual	2020-12-31	-4.59	—	USD/shares	10-K	2023-02-21
Annual	2021-12-31	-8.84	-92.6%	USD/shares	10-K/A	2024-02-29
Annual	2022-12-31	-6.15	+30.4%	USD/shares	10-K	2025-02-28
Annual	2023-12-31	-4.45	+27.6%	USD/shares	10-K	2026-02-24
Annual	2024-12-31	-1.6	+64.0%	USD/shares	10-K	2026-02-24
Annual	2025-12-31	0.18	+111.2%	USD/shares	10-K	2026-02-24

EPS Diluted

Q: 14 | A: 6

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2021-06-30	-2.72	—	USD/shares	10-Q	2022-08-08
Quarterly	2021-09-30	-2.28	+16.2%	USD/shares	10-Q	2022-11-07
Quarterly	2022-03-31	-1.42	+37.7%	USD/shares	10-Q	2023-05-04
Quarterly	2022-06-30	-1.46	-2.8%	USD/shares	10-Q	2023-07-31
Quarterly	2022-09-30	-1.75	-19.9%	USD/shares	10-Q	2023-11-01
Quarterly	2023-03-31	-1.56	+10.9%	USD/shares	10-Q	2024-05-07
Quarterly	2023-06-30	-1.02	+34.6%	USD/shares	10-Q	2024-08-01
Quarterly	2023-09-30	-1.17	-14.7%	USD/shares	10-Q	2024-11-05
Quarterly	2024-03-31	-0.54	+53.8%	USD/shares	10-Q	2025-05-07
Quarterly	2024-06-30	-0.3	+44.4%	USD/shares	10-Q	2025-07-31
Quarterly	2024-09-30	-0.46	-53.3%	USD/shares	10-Q	2025-10-30
Quarterly	2025-03-31	-0.74	-60.9%	USD/shares	10-Q	2025-05-07
Quarterly	2025-06-30	-0.33	+55.4%	USD/shares	10-Q	2025-07-31
Quarterly	2025-09-30	1.67	+606.1%	USD/shares	10-Q	2025-10-30
Annual	2020-12-31	-4.59	—	USD/shares	10-K	2023-02-21
Annual	2021-12-31	-8.84	-92.6%	USD/shares	10-K/A	2024-02-29
Annual	2022-12-31	-6.15	+30.4%	USD/shares	10-K	2025-02-28
Annual	2023-12-31	-4.45	+27.6%	USD/shares	10-K	2026-02-24
Annual	2024-12-31	-1.6	+64.0%	USD/shares	10-K	2026-02-24
Annual	2025-12-31	0.2	+112.5%	USD/shares	10-K	2026-02-24

Balance Sheet

Metrics: 9

Cash and Equivalents

Q: 37 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-09-30	31408090.0	—	USD	10-Q	2017-12-20
Quarterly	2016-12-31	24863488.0	-20.8%	USD	10-Q	2018-11-13
Quarterly	2017-03-31	16436538.0	-33.9%	USD	10-Q	2018-04-30
Quarterly	2017-06-30	4939087.0	-70.0%	USD	10-Q	2018-07-31
Quarterly	2017-09-30	13135848.0	+166.0%	USD	10-Q	2018-11-13
Quarterly	2017-12-31	175643529.0	+1237.1%	USD	10-Q	2018-11-13
Quarterly	2018-03-31	152930977.0	-12.9%	USD	10-Q	2018-04-30
Quarterly	2018-06-30	253839540.0	+66.0%	USD	10-Q	2018-07-31
Quarterly	2018-09-30	220640818.0	-13.1%	USD	10-Q	2018-11-13
Quarterly	2018-12-31	176267666.0	-20.1%	USD	10-Q	2019-11-05
Quarterly	2019-03-31	288247000.0	+63.5%	USD	10-Q	2020-04-29
Quarterly	2019-06-30	289128000.0	+0.3%	USD	10-Q	2020-07-30
Quarterly	2019-09-30	433995000.0	+50.1%	USD	10-Q	2020-11-02
Quarterly	2019-12-31	351985000.0	-18.9%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	417881000.0	+18.7%	USD	10-Q	2021-04-28
Quarterly	2020-06-30	317348000.0	-24.1%	USD	10-Q	2021-08-09
Quarterly	2020-09-30	415560000.0	+30.9%	USD	10-Q	2021-11-08
Quarterly	2020-12-31	565779000.0	+36.1%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	265435000.0	-53.1%	USD	10-Q	2022-05-04
Quarterly	2021-06-30	270764000.0	+2.0%	USD	10-Q	2022-08-08
Quarterly	2021-09-30	283745000.0	+4.8%	USD	10-Q	2022-11-07
Quarterly	2021-12-31	640192000.0	+125.6%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	633456000.0	-1.1%	USD	10-Q	2023-05-04
Quarterly	2022-06-30	604489000.0	-4.6%	USD	10-Q	2023-07-31
Quarterly	2022-09-30	584189000.0	-3.4%	USD	10-Q	2023-11-01
Quarterly	2022-12-31	551801000.0	-5.5%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	765083000.0	+38.7%	USD	10-Q	2024-05-07
Quarterly	2023-06-30	616259000.0	-19.5%	USD	10-Q	2024-08-01
Quarterly	2023-09-30	452414000.0	-26.6%	USD	10-Q	2024-11-05
Quarterly	2023-12-31	351185000.0	-22.4%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	325923000.0	-7.2%	USD	10-Q	2025-05-07
Quarterly	2024-06-30	360087000.0	+10.5%	USD	10-Q	2025-07-31
Quarterly	2024-09-30	396864000.0	+10.2%	USD	10-Q	2025-10-30
Quarterly	2024-12-31	411290000.0	+3.6%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	358393000.0	-12.9%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	370036000.0	+3.2%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	479171000.0	+29.5%	USD	10-Q	2025-10-30
Annual	2016-12-31	24863488.0	—	USD	10-K	2018-03-19
Annual	2017-12-31	175643529.0	+606.4%	USD	10-K	2019-02-26
Annual	2018-12-31	176268000.0	+0.4%	USD	10-K	2021-02-25
Annual	2019-12-31	351985000.0	+99.7%	USD	10-K	2022-02-28
Annual	2020-12-31	565779000.0	+60.7%	USD	10-K	2023-02-21
Annual	2021-12-31	640192000.0	+13.2%	USD	10-K/A	2024-02-29
Annual	2022-12-31	551801000.0	-13.8%	USD	10-K	2025-02-28
Annual	2023-12-31	351185000.0	-36.4%	USD	10-K	2026-02-24
Annual	2024-12-31	411290000.0	+17.1%	USD	10-K	2026-02-24
Annual	2025-12-31	466233000.0	+13.4%	USD	10-K	2026-02-24

Accounts Receivable

Q: 18 | A: 5

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2021-06-30	719000.0	—	USD	10-Q	2021-08-09
Quarterly	2021-09-30	3522000.0	+389.8%	USD	10-Q	2021-11-08
Quarterly	2021-12-31	10103000.0	+186.9%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	6330000.0	-37.3%	USD	10-Q	2022-05-04
Quarterly	2022-06-30	7518000.0	+18.8%	USD	10-Q	2022-08-08
Quarterly	2022-09-30	8091000.0	+7.6%	USD	10-Q	2022-11-07
Quarterly	2022-12-31	7727000.0	-4.5%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	31505000.0	+307.7%	USD	10-Q	2023-05-04
Quarterly	2023-06-30	110913000.0	+252.0%	USD	10-Q	2023-07-31
Quarterly	2023-09-30	169258000.0	+52.6%	USD	10-Q	2023-11-01
Quarterly	2023-12-31	206442000.0	+22.0%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	267837000.0	+29.7%	USD	10-Q	2024-05-07
Quarterly	2024-06-30	304433000.0	+13.7%	USD	10-Q	2024-08-01
Quarterly	2024-09-30	279011000.0	-8.4%	USD	10-Q	2024-11-05
Quarterly	2024-12-31	264926000.0	-5.0%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	235246000.0	-11.2%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	214131000.0	-9.0%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	345538000.0	+61.4%	USD	10-Q	2025-10-30
Annual	2021-12-31	10103000.0	—	USD	10-K	2023-02-21
Annual	2022-12-31	7727000.0	-23.5%	USD	10-K/A	2024-02-29
Annual	2023-12-31	206442000.0	+2571.7%	USD	10-K	2025-02-28
Annual	2024-12-31	264926000.0	+28.3%	USD	10-K	2026-02-24
Annual	2025-12-31	366221000.0	+38.2%	USD	10-K	2026-02-24

Inventory

Q: 19 | A: 6

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2020-12-31	0.0	—	USD	10-Q	2021-11-08
Quarterly	2021-06-30	3731000.0	—	USD	10-Q	2021-08-09
Quarterly	2021-09-30	1677000.0	-55.1%	USD	10-Q	2021-11-08
Quarterly	2021-12-31	16286000.0	+871.1%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	32850000.0	+101.7%	USD	10-Q	2022-05-04
Quarterly	2022-06-30	48451000.0	+47.5%	USD	10-Q	2022-08-08
Quarterly	2022-09-30	59753000.0	+23.3%	USD	10-Q	2022-11-07
Quarterly	2022-12-31	85714000.0	+43.4%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	85484000.0	-0.3%	USD	10-Q	2023-05-04
Quarterly	2023-06-30	103216000.0	+20.7%	USD	10-Q	2023-07-31
Quarterly	2023-09-30	98545000.0	-4.5%	USD	10-Q	2023-11-01
Quarterly	2023-12-31	146362000.0	+48.5%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	161283000.0	+10.2%	USD	10-Q	2024-05-07
Quarterly	2024-06-30	152772000.0	-5.3%	USD	10-Q	2024-08-01
Quarterly	2024-09-30	121058000.0	-20.8%	USD	10-Q	2024-11-05
Quarterly	2024-12-31	81404000.0	-32.8%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	82468000.0	+1.3%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	121000000.0	+46.7%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	122819000.0	+1.5%	USD	10-Q	2025-10-30
Annual	2020-12-31	0.0	—	USD	10-K	2022-02-28
Annual	2021-12-31	16286000.0	—	USD	10-K	2023-02-21
Annual	2022-12-31	85714000.0	+426.3%	USD	10-K/A	2024-02-29
Annual	2023-12-31	146362000.0	+70.8%	USD	10-K	2025-02-28
Annual	2024-12-31	81404000.0	-44.4%	USD	10-K	2026-02-24
Annual	2025-12-31	142556000.0	+75.1%	USD	10-K	2026-02-24

Current Assets

Q: 34 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-12-31	27368730.0	—	USD	10-Q	2017-12-20
Quarterly	2017-09-30	19032933.0	-30.5%	USD	10-Q	2017-12-20
Quarterly	2017-12-31	182015306.0	+856.3%	USD	10-Q	2018-11-13
Quarterly	2018-03-31	163086857.0	-10.4%	USD	10-Q	2018-04-30
Quarterly	2018-06-30	266701518.0	+63.5%	USD	10-Q	2018-07-31
Quarterly	2018-09-30	238932792.0	-10.4%	USD	10-Q	2018-11-13
Quarterly	2018-12-31	202439221.0	-15.3%	USD	10-Q	2019-11-05
Quarterly	2019-03-31	310527863.0	+53.4%	USD	10-Q	2019-05-07
Quarterly	2019-06-30	308412717.0	-0.7%	USD	10-Q	2019-07-31
Quarterly	2019-09-30	451194872.0	+46.3%	USD	10-Q	2019-11-05
Quarterly	2019-12-31	373095000.0	-17.3%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	672407000.0	+80.2%	USD	10-Q	2020-04-29
Quarterly	2020-06-30	853825000.0	+27.0%	USD	10-Q	2020-07-30
Quarterly	2020-09-30	742349000.0	-13.1%	USD	10-Q	2020-11-02
Quarterly	2020-12-31	917192000.0	+23.6%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	773625000.0	-15.7%	USD	10-Q	2021-04-28
Quarterly	2021-06-30	655126000.0	-15.3%	USD	10-Q	2021-08-09
Quarterly	2021-09-30	475427000.0	-27.4%	USD	10-Q	2021-11-08
Quarterly	2021-12-31	824047000.0	+73.3%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	1103982000.0	+34.0%	USD	10-Q	2022-05-04
Quarterly	2022-06-30	959969000.0	-13.0%	USD	10-Q	2022-08-08
Quarterly	2022-09-30	831937000.0	-13.3%	USD	10-Q	2022-11-07
Quarterly	2022-12-31	719523000.0	-13.5%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	954255000.0	+32.6%	USD	10-Q	2023-05-04
Quarterly	2023-06-30	892686000.0	-6.5%	USD	10-Q	2023-07-31
Quarterly	2023-09-30	796767000.0	-10.7%	USD	10-Q	2023-11-01
Quarterly	2023-12-31	766331000.0	-3.8%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	811428000.0	+5.9%	USD	10-Q	2024-05-07
Quarterly	2024-06-30	859974000.0	+6.0%	USD	10-Q	2024-08-01
Quarterly	2024-09-30	833897000.0	-3.0%	USD	10-Q	2024-11-05
Quarterly	2024-12-31	788954000.0	-5.4%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	727718000.0	-7.8%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	755610000.0	+3.8%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	990676000.0	+31.1%	USD	10-Q	2025-10-30
Annual	2016-12-31	27368730.0	—	USD	10-K	2018-03-19
Annual	2017-12-31	182015306.0	+565.0%	USD	10-K	2019-02-26
Annual	2018-12-31	202439221.0	+11.2%	USD	10-K	2020-02-27
Annual	2019-12-31	373095000.0	+84.3%	USD	10-K	2021-02-25
Annual	2020-12-31	917192000.0	+145.8%	USD	10-K	2022-02-28
Annual	2021-12-31	824047000.0	-10.2%	USD	10-K	2023-02-21
Annual	2022-12-31	719523000.0	-12.7%	USD	10-K/A	2024-02-29
Annual	2023-12-31	766331000.0	+6.5%	USD	10-K	2025-02-28
Annual	2024-12-31	788954000.0	+3.0%	USD	10-K	2026-02-24
Annual	2025-12-31	1014840000.0	+28.6%	USD	10-K	2026-02-24

Total Assets

Q: 34 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-12-31	27433258.0	—	USD	10-Q	2017-12-20
Quarterly	2017-09-30	19141283.0	-30.2%	USD	10-Q	2017-12-20
Quarterly	2017-12-31	182131456.0	+851.5%	USD	10-Q	2018-11-13
Quarterly	2018-03-31	163203007.0	-10.4%	USD	10-Q	2018-04-30
Quarterly	2018-06-30	266817668.0	+63.5%	USD	10-Q	2018-07-31
Quarterly	2018-09-30	239145771.0	-10.4%	USD	10-Q	2018-11-13
Quarterly	2018-12-31	203533559.0	-14.9%	USD	10-Q	2019-11-05
Quarterly	2019-03-31	318353078.0	+56.4%	USD	10-Q	2019-05-07
Quarterly	2019-06-30	316704010.0	-0.5%	USD	10-Q	2019-07-31
Quarterly	2019-09-30	466356957.0	+47.3%	USD	10-Q	2019-11-05
Quarterly	2019-12-31	389245000.0	-16.5%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	688939000.0	+77.0%	USD	10-Q	2020-04-29
Quarterly	2020-06-30	870106000.0	+26.3%	USD	10-Q	2020-07-30
Quarterly	2020-09-30	768334000.0	-11.7%	USD	10-Q	2020-11-02
Quarterly	2020-12-31	960569000.0	+25.0%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	810129000.0	-15.7%	USD	10-Q	2021-04-28
Quarterly	2021-06-30	699912000.0	-13.6%	USD	10-Q	2021-08-09
Quarterly	2021-09-30	525689000.0	-24.9%	USD	10-Q	2021-11-08
Quarterly	2021-12-31	881765000.0	+67.7%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	1145854000.0	+30.0%	USD	10-Q	2022-05-04
Quarterly	2022-06-30	1002498000.0	-12.5%	USD	10-Q	2022-08-08
Quarterly	2022-09-30	872892000.0	-12.9%	USD	10-Q	2022-11-07
Quarterly	2022-12-31	760217000.0	-12.9%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	978869000.0	+28.8%	USD	10-Q	2023-05-04
Quarterly	2023-06-30	915578000.0	-6.5%	USD	10-Q	2023-07-31
Quarterly	2023-09-30	818216000.0	-10.6%	USD	10-Q	2023-11-01
Quarterly	2023-12-31	788730000.0	-3.6%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	831930000.0	+5.5%	USD	10-Q	2024-05-07
Quarterly	2024-06-30	904482000.0	+8.7%	USD	10-Q	2024-08-01
Quarterly	2024-09-30	901866000.0	-0.3%	USD	10-Q	2024-11-05
Quarterly	2024-12-31	885051000.0	-1.9%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	807285000.0	-8.8%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	821390000.0	+1.7%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	1058723000.0	+28.9%	USD	10-Q	2025-10-30
Annual	2016-12-31	27433258.0	—	USD	10-K	2018-03-19
Annual	2017-12-31	182131456.0	+563.9%	USD	10-K	2019-02-26
Annual	2018-12-31	203533559.0	+11.8%	USD	10-K	2020-02-27
Annual	2019-12-31	389245000.0	+91.2%	USD	10-K	2021-02-25
Annual	2020-12-31	960569000.0	+146.8%	USD	10-K	2022-02-28
Annual	2021-12-31	881765000.0	-8.2%	USD	10-K	2023-02-21
Annual	2022-12-31	760217000.0	-13.8%	USD	10-K/A	2024-02-29
Annual	2023-12-31	788730000.0	+3.8%	USD	10-K	2025-02-28
Annual	2024-12-31	885051000.0	+12.2%	USD	10-K	2026-02-24
Annual	2025-12-31	1075257000.0	+21.5%	USD	10-K	2026-02-24

Current Liabilities

Q: 34 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-12-31	3638938.0	—	USD	10-Q	2017-12-20
Quarterly	2017-09-30	6937944.0	+90.7%	USD	10-Q	2017-12-20
Quarterly	2017-12-31	6553958.0	-5.5%	USD	10-Q	2018-11-13
Quarterly	2018-03-31	7294859.0	+11.3%	USD	10-Q	2018-04-30
Quarterly	2018-06-30	10254195.0	+40.6%	USD	10-Q	2018-07-31
Quarterly	2018-09-30	16034440.0	+56.4%	USD	10-Q	2018-11-13
Quarterly	2018-12-31	17024607.0	+6.2%	USD	10-Q	2019-11-05
Quarterly	2019-03-31	20386473.0	+19.7%	USD	10-Q	2019-05-07
Quarterly	2019-06-30	35591073.0	+74.6%	USD	10-Q	2019-07-31
Quarterly	2019-09-30	44572363.0	+25.2%	USD	10-Q	2019-11-05
Quarterly	2019-12-31	65753000.0	+47.5%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	50740000.0	-22.8%	USD	10-Q	2020-04-29
Quarterly	2020-06-30	57990000.0	+14.3%	USD	10-Q	2020-07-30
Quarterly	2020-09-30	75273000.0	+29.8%	USD	10-Q	2020-11-02
Quarterly	2020-12-31	128327000.0	+70.5%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	83670000.0	-34.8%	USD	10-Q	2021-04-28
Quarterly	2021-06-30	157787000.0	+88.6%	USD	10-Q	2021-08-09
Quarterly	2021-09-30	94237000.0	-40.3%	USD	10-Q	2021-11-08
Quarterly	2021-12-31	131847000.0	+39.9%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	124769000.0	-5.4%	USD	10-Q	2022-05-04
Quarterly	2022-06-30	126793000.0	+1.6%	USD	10-Q	2022-08-08
Quarterly	2022-09-30	115446000.0	-8.9%	USD	10-Q	2022-11-07
Quarterly	2022-12-31	167610000.0	+45.2%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	138644000.0	-17.3%	USD	10-Q	2023-05-04
Quarterly	2023-06-30	174837000.0	+26.1%	USD	10-Q	2023-07-31
Quarterly	2023-09-30	185630000.0	+6.2%	USD	10-Q	2023-11-01
Quarterly	2023-12-31	247593000.0	+33.4%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	215291000.0	-13.0%	USD	10-Q	2024-05-07
Quarterly	2024-06-30	169168000.0	-21.4%	USD	10-Q	2024-08-01
Quarterly	2024-09-30	191260000.0	+13.1%	USD	10-Q	2024-11-05
Quarterly	2024-12-31	185509000.0	-3.0%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	178377000.0	-3.8%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	200659000.0	+12.5%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	279527000.0	+39.3%	USD	10-Q	2025-10-30
Annual	2016-12-31	3638938.0	—	USD	10-K	2018-03-19
Annual	2017-12-31	6553958.0	+80.1%	USD	10-K	2019-02-26
Annual	2018-12-31	17024607.0	+159.8%	USD	10-K	2020-02-27
Annual	2019-12-31	65753000.0	+286.2%	USD	10-K	2021-02-25
Annual	2020-12-31	128327000.0	+95.2%	USD	10-K	2022-02-28
Annual	2021-12-31	131847000.0	+2.7%	USD	10-K	2023-02-21
Annual	2022-12-31	167610000.0	+27.1%	USD	10-K/A	2024-02-29
Annual	2023-12-31	247593000.0	+47.7%	USD	10-K	2025-02-28
Annual	2024-12-31	185509000.0	-25.1%	USD	10-K	2026-02-24
Annual	2025-12-31	323596000.0	+74.4%	USD	10-K	2026-02-24

Total Liabilities

Q: 32 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2017-12-31	33188596.0	—	USD	10-Q	2018-11-13
Quarterly	2018-03-31	34160902.0	+2.9%	USD	10-Q	2018-04-30
Quarterly	2018-06-30	37265562.0	+9.1%	USD	10-Q	2018-07-31
Quarterly	2018-09-30	43190921.0	+15.9%	USD	10-Q	2018-11-13
Quarterly	2018-12-31	42560904.0	-1.5%	USD	10-Q	2019-11-05
Quarterly	2019-03-31	93598186.0	+119.9%	USD	10-Q	2019-05-07
Quarterly	2019-06-30	157617972.0	+68.4%	USD	10-Q	2019-07-31
Quarterly	2019-09-30	326795143.0	+107.3%	USD	10-Q	2019-11-05
Quarterly	2019-12-31	355016000.0	+8.6%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	429942000.0	+21.1%	USD	10-Q	2020-04-29
Quarterly	2020-06-30	638042000.0	+48.4%	USD	10-Q	2020-07-30
Quarterly	2020-09-30	662494000.0	+3.8%	USD	10-Q	2020-11-02
Quarterly	2020-12-31	756012000.0	+14.1%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	758471000.0	+0.3%	USD	10-Q	2021-04-28
Quarterly	2021-06-30	841405000.0	+10.9%	USD	10-Q	2021-08-09
Quarterly	2021-09-30	583014000.0	-30.7%	USD	10-Q	2021-11-08
Quarterly	2021-12-31	683103000.0	+17.2%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	683619000.0	+0.1%	USD	10-Q	2022-05-04
Quarterly	2022-06-30	668080000.0	-2.3%	USD	10-Q	2022-08-08
Quarterly	2022-09-30	565476000.0	-15.4%	USD	10-Q	2022-11-07
Quarterly	2022-12-31	590345000.0	+4.4%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	566746000.0	-4.0%	USD	10-Q	2023-05-04
Quarterly	2023-06-30	570175000.0	+0.6%	USD	10-Q	2023-07-31
Quarterly	2023-09-30	585945000.0	+2.8%	USD	10-Q	2023-11-01
Quarterly	2023-12-31	594209000.0	+1.4%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	565254000.0	-4.9%	USD	10-Q	2024-05-07
Quarterly	2024-06-30	640155000.0	+13.3%	USD	10-Q	2024-08-01
Quarterly	2024-09-30	664745000.0	+3.8%	USD	10-Q	2024-11-05
Quarterly	2024-12-31	656512000.0	-1.2%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	643069000.0	-2.0%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	665085000.0	+3.4%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	657555000.0	-1.1%	USD	10-Q	2025-10-30
Annual	2016-12-31	3638938.0	—	USD	10-K	2018-03-19
Annual	2017-12-31	33188596.0	+812.0%	USD	10-K	2019-02-26
Annual	2018-12-31	42560904.0	+28.2%	USD	10-K	2020-02-27
Annual	2019-12-31	355016000.0	+734.1%	USD	10-K	2021-02-25
Annual	2020-12-31	756012000.0	+113.0%	USD	10-K	2022-02-28
Annual	2021-12-31	683103000.0	-9.6%	USD	10-K	2023-02-21
Annual	2022-12-31	590345000.0	-13.6%	USD	10-K/A	2024-02-29
Annual	2023-12-31	594209000.0	+0.7%	USD	10-K	2025-02-28
Annual	2024-12-31	656512000.0	+10.5%	USD	10-K	2026-02-24
Annual	2025-12-31	705110000.0	+7.4%	USD	10-K	2026-02-24

Stockholders' Equity

Q: 34 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-12-31	23794320.0	—	USD	10-Q	2017-12-20
Quarterly	2017-09-30	12203339.0	-48.7%	USD	10-Q	2017-12-20
Quarterly	2017-12-31	148942860.0	+1120.5%	USD	10-Q	2019-11-05
Quarterly	2018-03-31	129042105.0	-13.4%	USD	10-Q	2019-11-05
Quarterly	2018-06-30	229552107.0	+77.9%	USD	10-Q	2019-11-05
Quarterly	2018-09-30	195954850.0	-14.6%	USD	10-Q	2019-11-05
Quarterly	2018-12-31	160972000.0	-17.9%	USD	10-Q	2020-11-02
Quarterly	2019-03-31	224755000.0	+39.6%	USD	10-Q	2020-11-02
Quarterly	2019-06-30	159086000.0	-29.2%	USD	10-Q	2020-11-02
Quarterly	2019-09-30	139562000.0	-12.3%	USD	10-Q	2020-11-02
Quarterly	2019-12-31	34229000.0	-75.5%	USD	10-Q	2021-11-08
Quarterly	2020-03-31	258997000.0	+656.7%	USD	10-Q	2021-11-08
Quarterly	2020-06-30	232064000.0	-10.4%	USD	10-Q	2021-11-08
Quarterly	2020-09-30	105840000.0	-54.4%	USD	10-Q	2021-11-08
Quarterly	2020-12-31	204557000.0	+93.3%	USD	10-Q	2022-11-07
Quarterly	2021-03-31	51658000.0	-74.7%	USD	10-Q	2022-11-07
Quarterly	2021-06-30	-141493000.0	-373.9%	USD	10-Q	2022-11-07
Quarterly	2021-09-30	-57325000.0	+59.5%	USD	10-Q	2022-11-07
Quarterly	2021-12-31	198662000.0	+446.6%	USD	10-Q	2023-11-01
Quarterly	2022-03-31	462235000.0	+132.7%	USD	10-Q	2023-11-01
Quarterly	2022-06-30	334418000.0	-27.7%	USD	10-Q	2023-11-01
Quarterly	2022-09-30	307416000.0	-8.1%	USD	10-Q	2023-11-01
Quarterly	2022-12-31	169872000.0	-44.7%	USD	10-Q	2024-11-05
Quarterly	2023-03-31	412123000.0	+142.6%	USD	10-Q	2024-11-05
Quarterly	2023-06-30	345403000.0	-16.2%	USD	10-Q	2024-11-05
Quarterly	2023-09-30	232271000.0	-32.8%	USD	10-Q	2024-11-05
Quarterly	2023-12-31	194521000.0	-16.3%	USD	10-Q	2025-10-30
Quarterly	2024-03-31	266676000.0	+37.1%	USD	10-Q	2025-10-30
Quarterly	2024-06-30	264327000.0	-0.9%	USD	10-Q	2025-10-30
Quarterly	2024-09-30	237121000.0	-10.3%	USD	10-Q	2025-10-30
Quarterly	2024-12-31	228539000.0	-3.6%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	164216000.0	-28.1%	USD	10-Q	2025-10-30
Quarterly	2025-06-30	156305000.0	-4.8%	USD	10-Q	2025-10-30
Quarterly	2025-09-30	401168000.0	+156.7%	USD	10-Q	2025-10-30
Annual	2016-12-31	23794320.0	—	USD	10-K	2020-02-27
Annual	2017-12-31	148942000.0	+526.0%	USD	10-K	2021-02-25
Annual	2018-12-31	160973000.0	+8.1%	USD	10-K	2022-02-28
Annual	2019-12-31	34229000.0	-78.7%	USD	10-K	2023-02-21
Annual	2020-12-31	204557000.0	+497.6%	USD	10-K/A	2024-02-29
Annual	2021-12-31	198662000.0	-2.9%	USD	10-K	2025-02-28
Annual	2022-12-31	169872000.0	-14.5%	USD	10-K	2026-02-24
Annual	2023-12-31	194521000.0	+14.5%	USD	10-K	2026-02-24
Annual	2024-12-31	228539000.0	+17.5%	USD	10-K	2026-02-24
Annual	2025-12-31	370147000.0	+62.0%	USD	10-K	2026-02-24

Long-Term Debt

Q: 7 | A: 3

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2018-03-31	27000000.0	—	USD	10-Q	2018-04-30
Quarterly	2018-06-30	27000000.0	+0.0%	USD	10-Q	2018-07-31
Quarterly	2018-09-30	27000000.0	+0.0%	USD	10-Q	2018-11-13
Quarterly	2023-03-31	92809000.0	+243.7%	USD	10-Q	2023-05-04
Quarterly	2023-06-30	92883000.0	+0.1%	USD	10-Q	2023-07-31
Quarterly	2023-09-30	92957000.0	+0.1%	USD	10-Q	2023-11-01
Quarterly	2024-03-31	93109000.0	+0.2%	USD	10-Q	2024-05-07
Annual	2017-12-31	27000000.0	—	USD	10-K	2018-03-19
Annual	2022-12-31	92736000.0	+243.5%	USD	10-K	2023-02-21
Annual	2023-12-31	93033000.0	+0.3%	USD	10-K/A	2024-02-29

Cash Flow

Metrics: 4

Operating Cash Flow

Q: 26 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2017-06-30	-19924401.0	—	USD	10-Q	2018-07-31
Quarterly	2017-09-30	-31062269.0	-55.9%	USD	10-Q	2018-11-13
Quarterly	2018-03-31	-22935249.0	+26.2%	USD	10-Q	2019-05-07
Quarterly	2018-06-30	-53630126.0	-133.8%	USD	10-Q	2019-07-31
Quarterly	2018-09-30	-86762574.0	-61.8%	USD	10-Q	2019-11-05
Quarterly	2019-03-31	-35560000.0	+59.0%	USD	10-Q	2020-04-29
Quarterly	2019-06-30	-75467000.0	-112.2%	USD	10-Q	2020-07-30
Quarterly	2019-09-30	-129064000.0	-71.0%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	-108349000.0	+16.1%	USD	10-Q	2021-04-28
Quarterly	2020-06-30	-202643000.0	-87.0%	USD	10-Q	2021-08-09
Quarterly	2020-09-30	-302467000.0	-49.3%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	-153314000.0	+49.3%	USD	10-Q	2022-05-04
Quarterly	2021-06-30	-282002000.0	-83.9%	USD	10-Q	2022-08-08
Quarterly	2021-09-30	-450627000.0	-59.8%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	-111560000.0	+75.2%	USD	10-Q	2023-05-04
Quarterly	2022-06-30	-218584000.0	-95.9%	USD	10-Q	2023-07-31
Quarterly	2022-09-30	-373001000.0	-70.6%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	-177620000.0	+52.4%	USD	10-Q	2024-05-07
Quarterly	2023-06-30	-327775000.0	-84.5%	USD	10-Q	2024-08-01
Quarterly	2023-09-30	-496860000.0	-51.6%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	-132983000.0	+73.2%	USD	10-Q	2025-05-07
Quarterly	2024-06-30	-141322000.0	-6.3%	USD	10-Q	2025-07-31
Quarterly	2024-09-30	-107226000.0	+24.1%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	-53410000.0	+50.2%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	-48965000.0	+8.3%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	59503000.0	+221.5%	USD	10-Q	2025-10-30
Annual	2016-12-31	-26003078.0	—	USD	10-K	2019-02-26
Annual	2017-12-31	-46595073.0	-79.2%	USD	10-K	2020-02-27
Annual	2018-12-31	-131241000.0	-181.7%	USD	10-K	2021-02-25
Annual	2019-12-31	-211135000.0	-60.9%	USD	10-K	2022-02-28
Annual	2020-12-31	-160488000.0	+24.0%	USD	10-K	2023-02-21
Annual	2021-12-31	-563126000.0	-250.9%	USD	10-K/A	2024-02-29
Annual	2022-12-31	-513745000.0	+8.8%	USD	10-K	2025-02-28
Annual	2023-12-31	-594735000.0	-15.8%	USD	10-K	2026-02-24
Annual	2024-12-31	-87866000.0	+85.2%	USD	10-K	2026-02-24
Annual	2025-12-31	45327000.0	+151.6%	USD	10-K	2026-02-24

Investing Cash Flow

Q: 21 | A: 7

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2019-03-31	-875000.0	—	USD	10-Q	2020-04-29
Quarterly	2019-06-30	-1067000.0	-21.9%	USD	10-Q	2020-07-30
Quarterly	2019-09-30	-1538000.0	-44.1%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	-227854000.0	-14715.0%	USD	10-Q	2021-04-28
Quarterly	2020-06-30	-515661000.0	-126.3%	USD	10-Q	2021-08-09
Quarterly	2020-09-30	-316898000.0	+38.5%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	-146765000.0	+53.7%	USD	10-Q	2022-05-04
Quarterly	2021-06-30	-17013000.0	+88.4%	USD	10-Q	2022-08-08
Quarterly	2021-09-30	162636000.0	+1056.0%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	-271949000.0	-267.2%	USD	10-Q	2023-05-04
Quarterly	2022-06-30	-189020000.0	+30.5%	USD	10-Q	2023-07-31
Quarterly	2022-09-30	-64236000.0	+66.0%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	-259000.0	+99.6%	USD	10-Q	2024-05-07
Quarterly	2023-06-30	-631000.0	-143.6%	USD	10-Q	2024-08-01
Quarterly	2023-09-30	-678000.0	-7.4%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	-293000.0	+56.8%	USD	10-Q	2025-05-07
Quarterly	2024-06-30	-383000.0	-30.7%	USD	10-Q	2025-07-31
Quarterly	2024-09-30	-383000.0	+0.0%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	-8000.0	+97.9%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	-57000.0	-612.5%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	-205000.0	-259.6%	USD	10-Q	2025-10-30
Annual	2019-12-31	-1693000.0	—	USD	10-K	2022-02-28
Annual	2020-12-31	-316989000.0	-18623.5%	USD	10-K	2023-02-21
Annual	2021-12-31	247616000.0	+178.1%	USD	10-K/A	2024-02-29
Annual	2022-12-31	59893000.0	-75.8%	USD	10-K	2025-02-28
Annual	2023-12-31	-674000.0	-101.1%	USD	10-K	2026-02-24
Annual	2024-12-31	-403000.0	+40.2%	USD	10-K	2026-02-24
Annual	2025-12-31	-313000.0	+22.3%	USD	10-K	2026-02-24

Financing Cash Flow

Q: 25 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2017-09-30	19334629.0	—	USD	10-Q	2018-11-13
Quarterly	2018-03-31	222697.0	-98.8%	USD	10-Q	2019-05-07
Quarterly	2018-06-30	131826137.0	+59095.3%	USD	10-Q	2019-07-31
Quarterly	2018-09-30	131787703.0	-0.0%	USD	10-Q	2019-11-05
Quarterly	2019-03-31	148418000.0	+12.6%	USD	10-Q	2020-04-29
Quarterly	2019-06-30	189382000.0	+27.6%	USD	10-Q	2020-07-30
Quarterly	2019-09-30	388332000.0	+105.1%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	403267000.0	+3.8%	USD	10-Q	2021-04-28
Quarterly	2020-06-30	684935000.0	+69.8%	USD	10-Q	2021-08-09
Quarterly	2020-09-30	685861000.0	+0.1%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	1632000.0	-99.8%	USD	10-Q	2022-05-04
Quarterly	2021-06-30	6158000.0	+277.3%	USD	10-Q	2022-08-08
Quarterly	2021-09-30	8278000.0	+34.4%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	376704000.0	+4450.7%	USD	10-Q	2023-05-04
Quarterly	2022-06-30	371969000.0	-1.3%	USD	10-Q	2023-07-31
Quarterly	2022-09-30	381605000.0	+2.6%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	391106000.0	+2.5%	USD	10-Q	2024-05-07
Quarterly	2023-06-30	392666000.0	+0.4%	USD	10-Q	2024-08-01
Quarterly	2023-09-30	398412000.0	+1.5%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	108212000.0	-72.8%	USD	10-Q	2025-05-07
Quarterly	2024-06-30	150699000.0	+39.3%	USD	10-Q	2025-07-31
Quarterly	2024-09-30	153241000.0	+1.7%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	274000.0	-99.8%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	6832000.0	+2393.4%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	7625000.0	+11.6%	USD	10-Q	2025-10-30
Annual	2016-12-31	14863020.0	—	USD	10-K	2019-02-26
Annual	2017-12-31	197375114.0	+1228.0%	USD	10-K	2020-02-27
Annual	2018-12-31	131903000.0	-33.2%	USD	10-K	2021-02-25
Annual	2019-12-31	388541000.0	+194.6%	USD	10-K	2022-02-28
Annual	2020-12-31	692178000.0	+78.1%	USD	10-K	2023-02-21
Annual	2021-12-31	392236000.0	-43.3%	USD	10-K/A	2024-02-29
Annual	2022-12-31	365659000.0	-6.8%	USD	10-K	2025-02-28
Annual	2023-12-31	394499000.0	+7.9%	USD	10-K	2026-02-24
Annual	2024-12-31	149241000.0	-62.2%	USD	10-K	2026-02-24
Annual	2025-12-31	8884000.0	-94.0%	USD	10-K	2026-02-24

Capital Expenditures

Q: 21 | A: 7

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2019-03-31	875000.0	—	USD	10-Q	2020-04-29
Quarterly	2019-06-30	1067000.0	+21.9%	USD	10-Q	2020-07-30
Quarterly	2019-09-30	1538000.0	+44.1%	USD	10-Q	2020-11-02
Quarterly	2020-03-31	435000.0	-71.7%	USD	10-Q	2021-04-28
Quarterly	2020-06-30	973000.0	+123.7%	USD	10-Q	2021-08-09
Quarterly	2020-09-30	4711000.0	+384.2%	USD	10-Q	2021-11-08
Quarterly	2021-03-31	484000.0	-89.7%	USD	10-Q	2022-05-04
Quarterly	2021-06-30	732000.0	+51.2%	USD	10-Q	2022-08-08
Quarterly	2021-09-30	1084000.0	+48.1%	USD	10-Q	2022-11-07
Quarterly	2022-03-31	86000.0	-92.1%	USD	10-Q	2023-05-04
Quarterly	2022-06-30	477000.0	+454.7%	USD	10-Q	2023-07-31
Quarterly	2022-09-30	673000.0	+41.1%	USD	10-Q	2023-11-01
Quarterly	2023-03-31	259000.0	-61.5%	USD	10-Q	2024-05-07
Quarterly	2023-06-30	631000.0	+143.6%	USD	10-Q	2024-08-01
Quarterly	2023-09-30	678000.0	+7.4%	USD	10-Q	2024-11-05
Quarterly	2024-03-31	293000.0	-56.8%	USD	10-Q	2025-05-07
Quarterly	2024-06-30	383000.0	+30.7%	USD	10-Q	2025-07-31
Quarterly	2024-09-30	383000.0	+0.0%	USD	10-Q	2025-10-30
Quarterly	2025-03-31	8000.0	-97.9%	USD	10-Q	2025-05-07
Quarterly	2025-06-30	57000.0	+612.5%	USD	10-Q	2025-07-31
Quarterly	2025-09-30	205000.0	+259.6%	USD	10-Q	2025-10-30
Annual	2019-12-31	1693000.0	—	USD	10-K	2022-02-28
Annual	2020-12-31	5422000.0	+220.3%	USD	10-K	2023-02-21
Annual	2021-12-31	1103000.0	-79.7%	USD	10-K/A	2024-02-29
Annual	2022-12-31	1524000.0	+38.2%	USD	10-K	2025-02-28
Annual	2023-12-31	773000.0	-49.3%	USD	10-K	2026-02-24
Annual	2024-12-31	403000.0	-47.9%	USD	10-K	2026-02-24
Annual	2025-12-31	313000.0	-22.3%	USD	10-K	2026-02-24

Share Data

Metrics: 4

Shares Outstanding

Q: 34 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-12-31	8428366.0	—	shares	10-Q	2017-12-20
Quarterly	2017-09-30	8472903.0	+0.5%	shares	10-Q	2017-12-20
Quarterly	2017-12-31	50334152.0	+494.1%	shares	10-Q	2018-11-13
Quarterly	2018-03-31	50429020.0	+0.2%	shares	10-Q	2018-04-30
Quarterly	2018-06-30	56154438.0	+11.4%	shares	10-Q	2018-07-31
Quarterly	2018-09-30	56242571.0	+0.2%	shares	10-Q	2018-11-13
Quarterly	2018-12-31	56279307.0	+0.1%	shares	10-Q	2019-11-05
Quarterly	2019-03-31	63218476.0	+12.3%	shares	10-Q	2019-05-07
Quarterly	2019-06-30	63672430.0	+0.7%	shares	10-Q	2019-07-31
Quarterly	2019-09-30	63872762.0	+0.3%	shares	10-Q	2019-11-05
Quarterly	2019-12-31	63900000.0	+0.0%	shares	10-Q	2020-11-02
Quarterly	2020-03-31	75400000.0	+18.0%	shares	10-Q	2020-04-29
Quarterly	2020-06-30	75600000.0	+0.3%	shares	10-Q	2020-07-30
Quarterly	2020-09-30	75700000.0	+0.1%	shares	10-Q	2020-11-02
Quarterly	2020-12-31	76130000.0	+0.6%	shares	10-Q	2021-11-08
Quarterly	2021-03-31	80438000.0	+5.7%	shares	10-Q	2021-04-28
Quarterly	2021-06-30	80956000.0	+0.6%	shares	10-Q	2021-08-09
Quarterly	2021-09-30	87219000.0	+7.7%	shares	10-Q	2021-11-08
Quarterly	2021-12-31	97524000.0	+11.8%	shares	10-Q	2022-11-07
Quarterly	2022-03-31	106440000.0	+9.1%	shares	10-Q	2022-05-04
Quarterly	2022-06-30	106841000.0	+0.4%	shares	10-Q	2022-08-08
Quarterly	2022-09-30	110476000.0	+3.4%	shares	10-Q	2022-11-07
Quarterly	2022-12-31	110772000.0	+0.3%	shares	10-Q	2023-11-01
Quarterly	2023-03-31	116179000.0	+4.9%	shares	10-Q	2023-05-04
Quarterly	2023-06-30	117579000.0	+1.2%	shares	10-Q	2023-07-31
Quarterly	2023-09-30	118359000.0	+0.7%	shares	10-Q	2023-11-01
Quarterly	2023-12-31	119556000.0	+1.0%	shares	10-Q	2024-11-05
Quarterly	2024-03-31	121267000.0	+1.4%	shares	10-Q	2024-05-07
Quarterly	2024-06-30	121687000.0	+0.3%	shares	10-Q	2024-08-01
Quarterly	2024-09-30	122069000.0	+0.3%	shares	10-Q	2024-11-05
Quarterly	2024-12-31	124495000.0	+2.0%	shares	10-Q	2025-10-30
Quarterly	2025-03-31	125661000.0	+0.9%	shares	10-Q	2025-05-07
Quarterly	2025-06-30	126187000.0	+0.4%	shares	10-Q	2025-07-31
Quarterly	2025-09-30	126500000.0	+0.2%	shares	10-Q	2025-10-30
Annual	2016-12-31	8428366.0	—	shares	10-K	2018-03-19
Annual	2017-12-31	50334152.0	+497.2%	shares	10-K	2019-02-26
Annual	2018-12-31	56279307.0	+11.8%	shares	10-K	2020-02-27
Annual	2019-12-31	63938000.0	+13.6%	shares	10-K	2021-02-25
Annual	2020-12-31	76130000.0	+19.1%	shares	10-K	2022-02-28
Annual	2021-12-31	97524000.0	+28.1%	shares	10-K	2023-02-21
Annual	2022-12-31	110772000.0	+13.6%	shares	10-K/A	2024-02-29
Annual	2023-12-31	119556000.0	+7.9%	shares	10-K	2025-02-28
Annual	2024-12-31	124495000.0	+4.1%	shares	10-K	2026-02-24
Annual	2025-12-31	126621000.0	+1.7%	shares	10-K	2026-02-24

Shares Issued

Q: 34 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-12-31	8428366.0	—	shares	10-Q	2017-12-20
Quarterly	2017-09-30	8472903.0	+0.5%	shares	10-Q	2017-12-20
Quarterly	2017-12-31	50334152.0	+494.1%	shares	10-Q	2018-11-13
Quarterly	2018-03-31	50429020.0	+0.2%	shares	10-Q	2018-04-30
Quarterly	2018-06-30	56154438.0	+11.4%	shares	10-Q	2018-07-31
Quarterly	2018-09-30	56242571.0	+0.2%	shares	10-Q	2018-11-13
Quarterly	2018-12-31	56279307.0	+0.1%	shares	10-Q	2019-11-05
Quarterly	2019-03-31	63218476.0	+12.3%	shares	10-Q	2019-05-07
Quarterly	2019-06-30	63672430.0	+0.7%	shares	10-Q	2019-07-31
Quarterly	2019-09-30	63872762.0	+0.3%	shares	10-Q	2019-11-05
Quarterly	2019-12-31	63900000.0	+0.0%	shares	10-Q	2020-11-02
Quarterly	2020-03-31	75400000.0	+18.0%	shares	10-Q	2020-04-29
Quarterly	2020-06-30	75600000.0	+0.3%	shares	10-Q	2020-07-30
Quarterly	2020-09-30	75700000.0	+0.1%	shares	10-Q	2020-11-02
Quarterly	2020-12-31	76130000.0	+0.6%	shares	10-Q	2021-11-08
Quarterly	2021-03-31	80438000.0	+5.7%	shares	10-Q	2021-04-28
Quarterly	2021-06-30	80956000.0	+0.6%	shares	10-Q	2021-08-09
Quarterly	2021-09-30	87219000.0	+7.7%	shares	10-Q	2021-11-08
Quarterly	2021-12-31	97524000.0	+11.8%	shares	10-Q	2022-11-07
Quarterly	2022-03-31	106440000.0	+9.1%	shares	10-Q	2022-05-04
Quarterly	2022-06-30	106841000.0	+0.4%	shares	10-Q	2022-08-08
Quarterly	2022-09-30	110476000.0	+3.4%	shares	10-Q	2022-11-07
Quarterly	2022-12-31	110772000.0	+0.3%	shares	10-Q	2023-11-01
Quarterly	2023-03-31	116179000.0	+4.9%	shares	10-Q	2023-05-04
Quarterly	2023-06-30	117579000.0	+1.2%	shares	10-Q	2023-07-31
Quarterly	2023-09-30	118359000.0	+0.7%	shares	10-Q	2023-11-01
Quarterly	2023-12-31	119556000.0	+1.0%	shares	10-Q	2024-11-05
Quarterly	2024-03-31	121267000.0	+1.4%	shares	10-Q	2024-05-07
Quarterly	2024-06-30	121687000.0	+0.3%	shares	10-Q	2024-08-01
Quarterly	2024-09-30	122069000.0	+0.3%	shares	10-Q	2024-11-05
Quarterly	2024-12-31	124495000.0	+2.0%	shares	10-Q	2025-10-30
Quarterly	2025-03-31	125661000.0	+0.9%	shares	10-Q	2025-05-07
Quarterly	2025-06-30	126187000.0	+0.4%	shares	10-Q	2025-07-31
Quarterly	2025-09-30	126500000.0	+0.2%	shares	10-Q	2025-10-30
Annual	2016-12-31	8428366.0	—	shares	10-K	2018-03-19
Annual	2017-12-31	50334152.0	+497.2%	shares	10-K	2019-02-26
Annual	2018-12-31	56279307.0	+11.8%	shares	10-K	2020-02-27
Annual	2019-12-31	63938000.0	+13.6%	shares	10-K	2021-02-25
Annual	2020-12-31	76130000.0	+19.1%	shares	10-K	2022-02-28
Annual	2021-12-31	97524000.0	+28.1%	shares	10-K	2023-02-21
Annual	2022-12-31	110772000.0	+13.6%	shares	10-K/A	2024-02-29
Annual	2023-12-31	119556000.0	+7.9%	shares	10-K	2025-02-28
Annual	2024-12-31	124495000.0	+4.1%	shares	10-K	2026-02-24
Annual	2025-12-31	126621000.0	+1.7%	shares	10-K	2026-02-24

Weighted Avg Shares Basic

Q: 14 | A: 6

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2021-06-30	80654.0	—	shares	10-Q	2022-08-08
Quarterly	2021-09-30	85661.0	+6.2%	shares	10-Q	2022-11-07
Quarterly	2022-03-31	98069.0	+14.5%	shares	10-Q	2023-05-04
Quarterly	2022-06-30	106630.0	+8.7%	shares	10-Q	2023-07-31
Quarterly	2022-09-30	109126.0	+2.3%	shares	10-Q	2023-11-01
Quarterly	2023-03-31	113872.0	+4.3%	shares	10-Q	2024-05-07
Quarterly	2023-06-30	119316000.0	+104680.8%	shares	10-Q	2024-08-01
Quarterly	2023-09-30	120292000.0	+0.8%	shares	10-Q	2024-11-05
Quarterly	2024-03-31	122956835.0	+2.2%	shares	10-Q	2025-05-07
Quarterly	2024-06-30	123904000.0	+0.8%	shares	10-Q	2025-07-31
Quarterly	2024-09-30	124234000.0	+0.3%	shares	10-Q	2025-10-30
Quarterly	2025-03-31	125452525.0	+1.0%	shares	10-Q	2025-05-07
Quarterly	2025-06-30	126024000.0	+0.5%	shares	10-Q	2025-07-31
Quarterly	2025-09-30	126424000.0	+0.3%	shares	10-Q	2025-10-30
Annual	2020-12-31	75163000.0	—	shares	10-K	2023-02-21
Annual	2021-12-31	84421000.0	+12.3%	shares	10-K/A	2024-02-29
Annual	2022-12-31	106114000.0	+25.7%	shares	10-K	2025-02-28
Annual	2023-12-31	118678000.0	+11.8%	shares	10-K	2026-02-24
Annual	2024-12-31	123905000.0	+4.4%	shares	10-K	2026-02-24
Annual	2025-12-31	126145000.0	+1.8%	shares	10-K	2026-02-24

Weighted Avg Shares Diluted

Q: 28 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-09-30	8428366.0	—	shares	10-Q	2017-12-20
Quarterly	2017-03-31	8428366.0	+0.0%	shares	10-Q	2018-04-30
Quarterly	2017-06-30	8428366.0	+0.0%	shares	10-Q	2018-07-31
Quarterly	2017-09-30	8442072.0	+0.2%	shares	10-Q	2018-11-13
Quarterly	2018-03-31	50353812.0	+496.5%	shares	10-Q	2019-05-07
Quarterly	2018-06-30	54691833.0	+8.6%	shares	10-Q	2019-07-31
Quarterly	2018-09-30	56201299.0	+2.8%	shares	10-Q	2019-11-05
Quarterly	2019-03-31	57897.0	-99.9%	shares	10-Q	2020-04-29
Quarterly	2019-06-30	63264.0	+9.3%	shares	10-Q	2020-07-30
Quarterly	2019-09-30	63753.0	+0.8%	shares	10-Q	2020-11-02
Quarterly	2020-03-31	73720000.0	+115533.8%	shares	10-Q	2021-04-28
Quarterly	2020-06-30	75550000.0	+2.5%	shares	10-Q	2021-08-09
Quarterly	2020-09-30	75628000.0	+0.1%	shares	10-Q	2021-11-08
Quarterly	2021-03-31	79219000.0	+4.7%	shares	10-Q	2022-05-04
Quarterly	2021-06-30	80654.0	-99.9%	shares	10-Q	2022-08-08
Quarterly	2021-09-30	85661.0	+6.2%	shares	10-Q	2022-11-07
Quarterly	2022-03-31	98069.0	+14.5%	shares	10-Q	2023-05-04
Quarterly	2022-06-30	106630.0	+8.7%	shares	10-Q	2023-07-31
Quarterly	2022-09-30	109126.0	+2.3%	shares	10-Q	2023-11-01
Quarterly	2023-03-31	113872.0	+4.3%	shares	10-Q	2024-05-07
Quarterly	2023-06-30	119316000.0	+104680.8%	shares	10-Q	2024-08-01
Quarterly	2023-09-30	120292000.0	+0.8%	shares	10-Q	2024-11-05
Quarterly	2024-03-31	122956835.0	+2.2%	shares	10-Q	2025-05-07
Quarterly	2024-06-30	123904000.0	+0.8%	shares	10-Q	2025-07-31
Quarterly	2024-09-30	124234000.0	+0.3%	shares	10-Q	2025-10-30
Quarterly	2025-03-31	125452525.0	+1.0%	shares	10-Q	2025-05-07
Quarterly	2025-06-30	126024000.0	+0.5%	shares	10-Q	2025-07-31
Quarterly	2025-09-30	130067000.0	+3.2%	shares	10-Q	2025-10-30
Annual	2016-12-31	8428366.0	—	shares	10-K	2019-02-26
Annual	2017-12-31	13870949.0	+64.6%	shares	10-K	2020-02-27
Annual	2018-12-31	54396000.0	+292.2%	shares	10-K	2021-02-25
Annual	2019-12-31	62229000.0	+14.4%	shares	10-K	2022-02-28
Annual	2020-12-31	75163000.0	+20.8%	shares	10-K	2023-02-21
Annual	2021-12-31	84421000.0	+12.3%	shares	10-K/A	2024-02-29
Annual	2022-12-31	106114000.0	+25.7%	shares	10-K	2025-02-28
Annual	2023-12-31	118678000.0	+11.8%	shares	10-K	2026-02-24
Annual	2024-12-31	123905000.0	+4.4%	shares	10-K	2026-02-24
Annual	2025-12-31	129855000.0	+4.8%	shares	10-K	2026-02-24

Credit and Bond Coverage

Company-level

Long-Term Debt (latest annual)

93,033,000

Total Liabilities (latest annual)

705,110,000

Current Liabilities (latest annual)

323,596,000

Metrics

Metrics: 8

Asset Turnover

Efficiency Q: 16 | A: 6

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2020-06-30	0.0000	—	ratio	10-Q	2021-08-09
Quarterly	2020-09-30	0.0008	—	ratio	10-Q	2021-11-08
Quarterly	2021-06-30	0.0009	+5.9%	ratio	10-Q	2022-08-08
Quarterly	2021-09-30	0.0107	+1107.5%	ratio	10-Q	2022-11-07
Quarterly	2022-03-31	0.0126	+16.8%	ratio	10-Q	2023-05-04
Quarterly	2022-06-30	0.0163	+29.7%	ratio	10-Q	2023-07-31
Quarterly	2022-09-30	0.0253	+55.2%	ratio	10-Q	2023-11-01
Quarterly	2023-03-31	0.0458	+81.3%	ratio	10-Q	2024-05-07
Quarterly	2023-06-30	0.1037	+126.4%	ratio	10-Q	2024-08-01
Quarterly	2023-09-30	0.1349	+30.1%	ratio	10-Q	2024-11-05
Quarterly	2024-03-31	0.2071	+53.5%	ratio	10-Q	2025-05-07
Quarterly	2024-06-30	0.2208	+6.6%	ratio	10-Q	2025-07-31
Quarterly	2024-09-30	0.2182	-1.1%	ratio	10-Q	2025-10-30
Quarterly	2025-03-31	0.2066	-5.3%	ratio	10-Q	2025-05-07
Quarterly	2025-06-30	0.2173	+5.2%	ratio	10-Q	2025-07-31
Quarterly	2025-09-30	0.4331	+99.3%	ratio	10-Q	2025-10-30
Annual	2020-12-31	0.2609	—	ratio	10-K	2023-02-21
Annual	2021-12-31	0.0755	-71.1%	ratio	10-K/A	2024-02-29
Annual	2022-12-31	0.0992	+31.4%	ratio	10-K	2025-02-28
Annual	2023-12-31	0.5028	+406.8%	ratio	10-K	2026-02-24
Annual	2024-12-31	0.8828	+75.6%	ratio	10-K	2026-02-24
Annual	2025-12-31	0.9335	+5.7%	ratio	10-K	2026-02-24

Current Ratio

Liquidity Q: 34 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-12-31	7.5211	—	ratio	10-Q	2017-12-20
Quarterly	2017-09-30	2.7433	-63.5%	ratio	10-Q	2017-12-20
Quarterly	2017-12-31	27.7718	+912.3%	ratio	10-Q	2018-11-13
Quarterly	2018-03-31	22.3564	-19.5%	ratio	10-Q	2018-04-30
Quarterly	2018-06-30	26.0090	+16.3%	ratio	10-Q	2018-07-31
Quarterly	2018-09-30	14.9012	-42.7%	ratio	10-Q	2018-11-13
Quarterly	2018-12-31	11.8910	-20.2%	ratio	10-Q	2019-11-05
Quarterly	2019-03-31	15.2321	+28.1%	ratio	10-Q	2019-05-07
Quarterly	2019-06-30	8.6655	-43.1%	ratio	10-Q	2019-07-31
Quarterly	2019-09-30	10.1227	+16.8%	ratio	10-Q	2019-11-05
Quarterly	2019-12-31	5.6742	-43.9%	ratio	10-Q	2020-11-02
Quarterly	2020-03-31	13.2520	+133.5%	ratio	10-Q	2020-04-29
Quarterly	2020-06-30	14.7237	+11.1%	ratio	10-Q	2020-07-30
Quarterly	2020-09-30	9.8621	-33.0%	ratio	10-Q	2020-11-02
Quarterly	2020-12-31	7.1473	-27.5%	ratio	10-Q	2021-11-08
Quarterly	2021-03-31	9.2461	+29.4%	ratio	10-Q	2021-04-28
Quarterly	2021-06-30	4.1520	-55.1%	ratio	10-Q	2021-08-09
Quarterly	2021-09-30	5.0450	+21.5%	ratio	10-Q	2021-11-08
Quarterly	2021-12-31	6.2500	+23.9%	ratio	10-Q	2022-11-07
Quarterly	2022-03-31	8.8482	+41.6%	ratio	10-Q	2022-05-04
Quarterly	2022-06-30	7.5712	-14.4%	ratio	10-Q	2022-08-08
Quarterly	2022-09-30	7.2063	-4.8%	ratio	10-Q	2022-11-07
Quarterly	2022-12-31	4.2928	-40.4%	ratio	10-Q	2023-11-01
Quarterly	2023-03-31	6.8828	+60.3%	ratio	10-Q	2023-05-04
Quarterly	2023-06-30	5.1058	-25.8%	ratio	10-Q	2023-07-31
Quarterly	2023-09-30	4.2922	-15.9%	ratio	10-Q	2023-11-01
Quarterly	2023-12-31	3.0951	-27.9%	ratio	10-Q	2024-11-05
Quarterly	2024-03-31	3.7690	+21.8%	ratio	10-Q	2024-05-07
Quarterly	2024-06-30	5.0836	+34.9%	ratio	10-Q	2024-08-01
Quarterly	2024-09-30	4.3600	-14.2%	ratio	10-Q	2024-11-05
Quarterly	2024-12-31	4.2529	-2.5%	ratio	10-Q	2025-10-30
Quarterly	2025-03-31	4.0797	-4.1%	ratio	10-Q	2025-05-07
Quarterly	2025-06-30	3.7656	-7.7%	ratio	10-Q	2025-07-31
Quarterly	2025-09-30	3.5441	-5.9%	ratio	10-Q	2025-10-30
Annual	2016-12-31	7.5211	—	ratio	10-K	2018-03-19
Annual	2017-12-31	27.7718	+269.3%	ratio	10-K	2019-02-26
Annual	2018-12-31	11.8910	-57.2%	ratio	10-K	2020-02-27
Annual	2019-12-31	5.6742	-52.3%	ratio	10-K	2021-02-25
Annual	2020-12-31	7.1473	+26.0%	ratio	10-K	2022-02-28
Annual	2021-12-31	6.2500	-12.6%	ratio	10-K	2023-02-21
Annual	2022-12-31	4.2928	-31.3%	ratio	10-K/A	2024-02-29
Annual	2023-12-31	3.0951	-27.9%	ratio	10-K	2025-02-28
Annual	2024-12-31	4.2529	+37.4%	ratio	10-K	2026-02-24
Annual	2025-12-31	3.1361	-26.3%	ratio	10-K	2026-02-24

Debt to Equity

Leverage Q: 32 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2017-12-31	0.2228	—	ratio	10-Q	2018-11-13
Quarterly	2018-03-31	0.2647	+18.8%	ratio	10-Q	2018-04-30
Quarterly	2018-06-30	0.1623	-38.7%	ratio	10-Q	2018-07-31
Quarterly	2018-09-30	0.2204	+35.8%	ratio	10-Q	2018-11-13
Quarterly	2018-12-31	0.2644	+20.0%	ratio	10-Q	2019-11-05
Quarterly	2019-03-31	0.4164	+57.5%	ratio	10-Q	2019-05-07
Quarterly	2019-06-30	0.9908	+137.9%	ratio	10-Q	2019-07-31
Quarterly	2019-09-30	2.3416	+136.3%	ratio	10-Q	2019-11-05
Quarterly	2019-12-31	10.3718	+342.9%	ratio	10-Q	2020-11-02
Quarterly	2020-03-31	1.6600	-84.0%	ratio	10-Q	2020-04-29
Quarterly	2020-06-30	2.7494	+65.6%	ratio	10-Q	2020-07-30
Quarterly	2020-09-30	6.2594	+127.7%	ratio	10-Q	2020-11-02
Quarterly	2020-12-31	3.6959	-41.0%	ratio	10-Q	2021-11-08
Quarterly	2021-03-31	14.6825	+297.3%	ratio	10-Q	2021-04-28
Quarterly	2021-06-30	-5.9466	-140.5%	ratio	10-Q	2021-08-09
Quarterly	2021-09-30	-10.1703	-71.0%	ratio	10-Q	2021-11-08
Quarterly	2021-12-31	3.4385	+133.8%	ratio	10-Q	2022-11-07
Quarterly	2022-03-31	1.4789	-57.0%	ratio	10-Q	2022-05-04
Quarterly	2022-06-30	1.9977	+35.1%	ratio	10-Q	2022-08-08
Quarterly	2022-09-30	1.8394	-7.9%	ratio	10-Q	2022-11-07
Quarterly	2022-12-31	3.4752	+88.9%	ratio	10-Q	2023-11-01
Quarterly	2023-03-31	1.3752	-60.4%	ratio	10-Q	2023-05-04
Quarterly	2023-06-30	1.6508	+20.0%	ratio	10-Q	2023-07-31
Quarterly	2023-09-30	2.5227	+52.8%	ratio	10-Q	2023-11-01
Quarterly	2023-12-31	3.0547	+21.1%	ratio	10-Q	2024-11-05
Quarterly	2024-03-31	2.1196	-30.6%	ratio	10-Q	2024-05-07
Quarterly	2024-06-30	2.4218	+14.3%	ratio	10-Q	2024-08-01
Quarterly	2024-09-30	2.8034	+15.8%	ratio	10-Q	2024-11-05
Quarterly	2024-12-31	2.8726	+2.5%	ratio	10-Q	2025-10-30
Quarterly	2025-03-31	3.9160	+36.3%	ratio	10-Q	2025-05-07
Quarterly	2025-06-30	4.2550	+8.7%	ratio	10-Q	2025-07-31
Quarterly	2025-09-30	1.6391	-61.5%	ratio	10-Q	2025-10-30
Annual	2016-12-31	0.1529	—	ratio	10-K	2018-03-19
Annual	2017-12-31	0.2228	+45.7%	ratio	10-K	2019-02-26
Annual	2018-12-31	0.2644	+18.7%	ratio	10-K	2020-02-27
Annual	2019-12-31	10.3718	+3822.8%	ratio	10-K	2021-02-25
Annual	2020-12-31	3.6959	-64.4%	ratio	10-K	2022-02-28
Annual	2021-12-31	3.4385	-7.0%	ratio	10-K	2023-02-21
Annual	2022-12-31	3.4752	+1.1%	ratio	10-K/A	2024-02-29
Annual	2023-12-31	3.0547	-12.1%	ratio	10-K	2025-02-28
Annual	2024-12-31	2.8726	-6.0%	ratio	10-K	2026-02-24
Annual	2025-12-31	1.9049	-33.7%	ratio	10-K	2026-02-24

Net Margin

Profitability Q: 15 | A: 6

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2020-09-30	-655.0139	—	ratio	10-Q	2021-11-08
Quarterly	2021-06-30	-351.8315	+46.3%	ratio	10-Q	2022-11-07
Quarterly	2021-09-30	-105.9152	+69.9%	ratio	10-Q	2022-11-07
Quarterly	2022-03-31	-9.6610	+90.9%	ratio	10-Q	2023-11-01
Quarterly	2022-06-30	-9.5562	+1.1%	ratio	10-Q	2023-11-01
Quarterly	2022-09-30	-22.0430	-130.7%	ratio	10-Q	2023-11-01
Quarterly	2023-03-31	-3.9642	+82.0%	ratio	10-Q	2024-11-05
Quarterly	2023-06-30	-1.2850	+67.6%	ratio	10-Q	2024-11-05
Quarterly	2023-09-30	-3.9860	-210.2%	ratio	10-Q	2024-11-05
Quarterly	2024-03-31	-0.3855	+90.3%	ratio	10-Q	2025-10-30
Quarterly	2024-06-30	-0.1886	+51.1%	ratio	10-Q	2025-10-30
Quarterly	2024-09-30	-0.8206	-335.2%	ratio	10-Q	2025-10-30
Quarterly	2025-03-31	-0.5529	+32.6%	ratio	10-Q	2025-10-30
Quarterly	2025-06-30	-0.2361	+57.3%	ratio	10-Q	2025-10-30
Quarterly	2025-09-30	0.1774	+175.1%	ratio	10-Q	2025-10-30
Annual	2020-12-31	-1.3759	—	ratio	10-K	2023-02-21
Annual	2021-12-31	-11.2127	-714.9%	ratio	10-K/A	2024-02-29
Annual	2022-12-31	-8.6470	+22.9%	ratio	10-K	2025-02-28
Annual	2023-12-31	-1.3329	+84.6%	ratio	10-K	2026-02-24
Annual	2024-12-31	-0.2532	+81.0%	ratio	10-K	2026-02-24
Annual	2025-12-31	0.0223	+108.8%	ratio	10-K	2026-02-24

Operating Margin

Profitability Q: 15 | A: 6

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2020-09-30	-200.5449	—	ratio	10-Q	2021-11-08
Quarterly	2021-06-30	-311.8571	-55.5%	ratio	10-Q	2022-08-08
Quarterly	2021-09-30	-22.6540	+92.7%	ratio	10-Q	2022-11-07
Quarterly	2022-03-31	-8.9700	+60.4%	ratio	10-Q	2023-05-04
Quarterly	2022-06-30	-9.1057	-1.5%	ratio	10-Q	2023-07-31
Quarterly	2022-09-30	-6.9341	+23.8%	ratio	10-Q	2023-11-01
Quarterly	2023-03-31	-3.9041	+43.7%	ratio	10-Q	2024-05-07
Quarterly	2023-06-30	-1.2682	+67.5%	ratio	10-Q	2024-08-01
Quarterly	2023-09-30	-1.2417	+2.1%	ratio	10-Q	2024-11-05
Quarterly	2024-03-31	-0.3603	+71.0%	ratio	10-Q	2025-05-07
Quarterly	2024-06-30	-0.1474	+59.1%	ratio	10-Q	2025-07-31
Quarterly	2024-09-30	-0.2402	-62.9%	ratio	10-Q	2025-10-30
Quarterly	2025-03-31	-0.4996	-108.0%	ratio	10-Q	2025-05-07
Quarterly	2025-06-30	-0.1865	+62.7%	ratio	10-Q	2025-07-31
Quarterly	2025-09-30	0.4867	+361.0%	ratio	10-Q	2025-10-30
Annual	2020-12-31	-0.8527	—	ratio	10-K	2023-02-21
Annual	2021-12-31	-8.0567	-844.8%	ratio	10-K/A	2024-02-29
Annual	2022-12-31	-7.8838	+2.1%	ratio	10-K	2025-02-28
Annual	2023-12-31	-1.3039	+83.5%	ratio	10-K	2026-02-24
Annual	2024-12-31	-0.2111	+83.8%	ratio	10-K	2026-02-24
Annual	2025-12-31	0.0552	+126.2%	ratio	10-K	2026-02-24

Quick Ratio

Liquidity Q: 34 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-12-31	6.8326	—	ratio	10-Q	2018-11-13
Quarterly	2017-09-30	1.8933	-72.3%	ratio	10-Q	2018-11-13
Quarterly	2017-12-31	26.7996	+1315.5%	ratio	10-Q	2018-11-13
Quarterly	2018-03-31	20.9642	-21.8%	ratio	10-Q	2018-04-30
Quarterly	2018-06-30	24.7547	+18.1%	ratio	10-Q	2018-07-31
Quarterly	2018-09-30	13.7604	-44.4%	ratio	10-Q	2018-11-13
Quarterly	2018-12-31	10.3537	-24.8%	ratio	10-Q	2019-11-05
Quarterly	2019-03-31	14.1391	+36.6%	ratio	10-Q	2020-04-29
Quarterly	2019-06-30	8.1236	-42.5%	ratio	10-Q	2020-07-30
Quarterly	2019-09-30	9.7369	+19.9%	ratio	10-Q	2020-11-02
Quarterly	2019-12-31	5.3531	-45.0%	ratio	10-Q	2020-11-02
Quarterly	2020-03-31	8.2357	+53.8%	ratio	10-Q	2021-04-28
Quarterly	2020-06-30	5.4725	-33.6%	ratio	10-Q	2021-08-09
Quarterly	2020-09-30	5.5207	+0.9%	ratio	10-Q	2021-11-08
Quarterly	2020-12-31	4.4089	-20.1%	ratio	10-Q	2021-11-08
Quarterly	2021-03-31	3.1724	-28.0%	ratio	10-Q	2022-05-04
Quarterly	2021-06-30	1.7160	-45.9%	ratio	10-Q	2022-08-08
Quarterly	2021-09-30	3.0110	+75.5%	ratio	10-Q	2022-11-07
Quarterly	2021-12-31	4.8556	+61.3%	ratio	10-Q	2022-11-07
Quarterly	2022-03-31	5.0770	+4.6%	ratio	10-Q	2023-05-04
Quarterly	2022-06-30	4.7675	-6.1%	ratio	10-Q	2023-07-31
Quarterly	2022-09-30	5.0603	+6.1%	ratio	10-Q	2023-11-01
Quarterly	2022-12-31	3.2922	-34.9%	ratio	10-Q	2023-11-01
Quarterly	2023-03-31	5.5183	+67.6%	ratio	10-Q	2024-05-07
Quarterly	2023-06-30	3.5248	-36.1%	ratio	10-Q	2024-08-01
Quarterly	2023-09-30	2.4372	-30.9%	ratio	10-Q	2024-11-05
Quarterly	2023-12-31	1.4184	-41.8%	ratio	10-Q	2024-11-05
Quarterly	2024-03-31	1.5139	+6.7%	ratio	10-Q	2025-05-07
Quarterly	2024-06-30	2.1286	+40.6%	ratio	10-Q	2025-07-31
Quarterly	2024-09-30	2.0750	-2.5%	ratio	10-Q	2025-10-30
Quarterly	2024-12-31	2.2171	+6.8%	ratio	10-Q	2025-10-30
Quarterly	2025-03-31	2.0092	-9.4%	ratio	10-Q	2025-05-07
Quarterly	2025-06-30	1.8441	-8.2%	ratio	10-Q	2025-07-31
Quarterly	2025-09-30	1.7142	-7.0%	ratio	10-Q	2025-10-30
Annual	2016-12-31	6.8326	—	ratio	10-K	2018-03-19
Annual	2017-12-31	26.7996	+292.2%	ratio	10-K	2019-02-26
Annual	2018-12-31	10.3537	-61.4%	ratio	10-K	2021-02-25
Annual	2019-12-31	5.3531	-48.3%	ratio	10-K	2022-02-28
Annual	2020-12-31	4.4089	-17.6%	ratio	10-K	2023-02-21
Annual	2021-12-31	4.8556	+10.1%	ratio	10-K/A	2024-02-29
Annual	2022-12-31	3.2922	-32.2%	ratio	10-K	2025-02-28
Annual	2023-12-31	1.4184	-56.9%	ratio	10-K	2026-02-24
Annual	2024-12-31	2.2171	+56.3%	ratio	10-K	2026-02-24
Annual	2025-12-31	1.4408	-35.0%	ratio	10-K	2026-02-24

ROA

Profitability Q: 25 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2017-09-30	-0.6046	—	ratio	10-Q	2018-11-13
Quarterly	2018-03-31	-0.1332	+78.0%	ratio	10-Q	2019-11-05
Quarterly	2018-06-30	-0.1249	+6.2%	ratio	10-Q	2019-11-05
Quarterly	2018-09-30	-0.3789	-203.3%	ratio	10-Q	2019-11-05
Quarterly	2019-03-31	-0.1589	+58.1%	ratio	10-Q	2020-11-02
Quarterly	2019-06-30	-0.2245	-41.3%	ratio	10-Q	2020-11-02
Quarterly	2019-09-30	-0.4106	-82.9%	ratio	10-Q	2020-11-02
Quarterly	2020-03-31	-0.2450	+40.3%	ratio	10-Q	2021-11-08
Quarterly	2020-06-30	-0.1363	+44.4%	ratio	10-Q	2021-11-08
Quarterly	2020-09-30	-0.5507	-304.0%	ratio	10-Q	2021-11-08
Quarterly	2021-03-31	-0.2267	+58.8%	ratio	10-Q	2022-11-07
Quarterly	2021-06-30	-0.3132	-38.1%	ratio	10-Q	2022-11-07
Quarterly	2021-09-30	-1.1384	-263.5%	ratio	10-Q	2022-11-07
Quarterly	2022-03-31	-0.1213	+89.3%	ratio	10-Q	2023-11-01
Quarterly	2022-06-30	-0.1556	-28.3%	ratio	10-Q	2023-11-01
Quarterly	2022-09-30	-0.5570	-258.0%	ratio	10-Q	2023-11-01
Quarterly	2023-03-31	-0.1816	+67.4%	ratio	10-Q	2024-11-05
Quarterly	2023-06-30	-0.1333	+26.6%	ratio	10-Q	2024-11-05
Quarterly	2023-09-30	-0.5378	-303.5%	ratio	10-Q	2024-11-05
Quarterly	2024-03-31	-0.0798	+85.2%	ratio	10-Q	2025-10-30
Quarterly	2024-06-30	-0.0416	+47.9%	ratio	10-Q	2025-10-30
Quarterly	2024-09-30	-0.1791	-330.2%	ratio	10-Q	2025-10-30
Quarterly	2025-03-31	-0.1142	+36.2%	ratio	10-Q	2025-10-30
Quarterly	2025-06-30	-0.0513	+55.1%	ratio	10-Q	2025-10-30
Quarterly	2025-09-30	0.0768	+249.7%	ratio	10-Q	2025-10-30
Annual	2016-12-31	-0.9888	—	ratio	10-K	2019-02-26
Annual	2017-12-31	-0.2801	+71.7%	ratio	10-K	2020-02-27
Annual	2018-12-31	-0.6264	-123.7%	ratio	10-K	2021-02-25
Annual	2019-12-31	-0.7828	-25.0%	ratio	10-K	2022-02-28
Annual	2020-12-31	-0.3590	+54.1%	ratio	10-K	2023-02-21
Annual	2021-12-31	-0.8464	-135.8%	ratio	10-K/A	2024-02-29
Annual	2022-12-31	-0.8579	-1.4%	ratio	10-K	2025-02-28
Annual	2023-12-31	-0.6702	+21.9%	ratio	10-K	2026-02-24
Annual	2024-12-31	-0.2236	+66.6%	ratio	10-K	2026-02-24
Annual	2025-12-31	0.0208	+109.3%	ratio	10-K	2026-02-24

ROE

Profitability Q: 25 | A: 10

Quarterly

Annual

Show Data Rows

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2017-09-30	-0.9484	—	ratio	10-Q	2018-11-13
Quarterly	2018-03-31	-0.1684	+82.2%	ratio	10-Q	2019-11-05
Quarterly	2018-06-30	-0.1452	+13.8%	ratio	10-Q	2019-11-05
Quarterly	2018-09-30	-0.4624	-218.5%	ratio	10-Q	2019-11-05
Quarterly	2019-03-31	-0.2250	+51.3%	ratio	10-Q	2020-11-02
Quarterly	2019-06-30	-0.4469	-98.6%	ratio	10-Q	2020-11-02
Quarterly	2019-09-30	-1.3721	-207.0%	ratio	10-Q	2020-11-02
Quarterly	2020-03-31	-0.6518	+52.5%	ratio	10-Q	2021-11-08
Quarterly	2020-06-30	-0.5111	+21.6%	ratio	10-Q	2021-11-08
Quarterly	2020-09-30	-3.9979	-682.2%	ratio	10-Q	2021-11-08
Quarterly	2021-03-31	-3.5553	+11.1%	ratio	10-Q	2022-11-07
Quarterly	2021-06-30	1.5491	+143.6%	ratio	10-Q	2022-11-07
Quarterly	2021-09-30	10.4391	+573.9%	ratio	10-Q	2022-11-07
Quarterly	2022-03-31	-0.3006	-102.9%	ratio	10-Q	2023-11-01
Quarterly	2022-06-30	-0.4664	-55.2%	ratio	10-Q	2023-11-01
Quarterly	2022-09-30	-1.5815	-239.1%	ratio	10-Q	2023-11-01
Quarterly	2023-03-31	-0.4314	+72.7%	ratio	10-Q	2024-11-05
Quarterly	2023-06-30	-0.3533	+18.1%	ratio	10-Q	2024-11-05
Quarterly	2023-09-30	-1.8946	-436.2%	ratio	10-Q	2024-11-05
Quarterly	2024-03-31	-0.2491	+86.9%	ratio	10-Q	2025-10-30
Quarterly	2024-06-30	-0.1425	+42.8%	ratio	10-Q	2025-10-30
Quarterly	2024-09-30	-0.6812	-378.2%	ratio	10-Q	2025-10-30
Quarterly	2025-03-31	-0.5616	+17.6%	ratio	10-Q	2025-10-30
Quarterly	2025-06-30	-0.2697	+52.0%	ratio	10-Q	2025-10-30
Quarterly	2025-09-30	0.2028	+175.2%	ratio	10-Q	2025-10-30
Annual	2016-12-31	-1.1400	—	ratio	10-K	2019-02-26
Annual	2017-12-31	-0.3425	+70.0%	ratio	10-K	2020-02-27
Annual	2018-12-31	-0.7921	-131.3%	ratio	10-K	2021-02-25
Annual	2019-12-31	-8.9020	-1023.9%	ratio	10-K	2022-02-28
Annual	2020-12-31	-1.6860	+81.1%	ratio	10-K	2023-02-21
Annual	2021-12-31	-3.7569	-122.8%	ratio	10-K/A	2024-02-29
Annual	2022-12-31	-3.8392	-2.2%	ratio	10-K	2025-02-28
Annual	2023-12-31	-2.7176	+29.2%	ratio	10-K	2026-02-24
Annual	2024-12-31	-0.8658	+68.1%	ratio	10-K	2026-02-24
Annual	2025-12-31	0.0605	+107.0%	ratio	10-K	2026-02-24

8-K Material Event Details

46 filings · 83 item records

This 8-K section tracks corporate event disclosures, not insider buy/sell sentiment. Insider trading direction is shown in the insider section below.

Event Type Distribution

Count per 8-K item

Insider Transaction History

703 transaction records

Net Insider Flow

Monthly open-market buy value minus open-market sell value

Monthly Insider Activity Mix

Share volume split between open-market trades, grants, and exercises

Transaction Value Timeline

Each circle = one priced transaction; size ∝ value X-axis date:

All Transactions

Date	Insider	Title	Type	Security	Shares	Price	Total Value	Post-Tx Shares
2026-04-06	O'Brien Stephanie Monaghan	Dir	Other acquired transaction J	Common Stock	5,750	$0.00	$0	5,750
2026-03-11	Francois Cedric	Chief Executive Officer	Equity grant / award G	Common Stock	64,869	$0.00	$0	372,815
2026-02-27	Dolsten Mikael	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	24,135	$20.96	$505,870	24,135
2026-02-27	Dolsten Mikael	Dir	Equity grant / award A	Common Stock	14,312	$0.00	$0	14,312
2026-02-11	DeLong Mark Jeffrey	Chief Business & Strat Officer	Open-market sell S	Common Stock	368	$22.15	$8,153	114,591
2026-02-03	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	8,840	$0.00	$0	0
2026-02-03	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	8,840	$3.76	$33,238	490,837
2026-01-28	Boucher Kelley	Chief People Officer	Equity grant / award A	Common Stock	30,146	$0.00	$0	127,804
2026-01-22	Baumal Caroline	Chief Medical Officer	Open-market sell S	Common Stock	2,797	$21.77	$60,878	86,527
2026-01-20	Baumal Caroline	Chief Medical Officer	Open-market sell S	Common Stock	1,882	$19.79	$37,250	89,324
2026-01-13	Chopas James George	VP/Chief Accounting Officer	Open-market sell S	Common Stock	873	$22.19	$19,369	52,595
2026-01-07	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	888	$0.00	$0	14,000
2026-01-07	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	888	$14.95	$13,276	104,618
2026-01-05	Baumal Caroline	Chief Medical Officer	Open-market sell S	Common Stock	3,020	$25.53	$77,097	91,206
2026-01-01	Machiels Alec	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	14,684	$0.00	$0	14,684
2026-01-01	Machiels Alec	Dir	Equity grant / award A	Common Stock	7,961	$0.00	$0	384,989
2025-12-16	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,000	$24.49	$122,450	103,730
2025-11-17	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,000	$20.06	$100,300	108,730
2025-10-21	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	232,903
2025-10-21	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	10,000	$28.03	$280,300	110,936
2025-10-21	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M	Common Stock	10,000	$10.03	$100,300	120,936
2025-10-16	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,000	$25.22	$126,100	113,730
2025-10-10	Dunlop A. Sinclair	—	Other disposed transaction J	Common Stock	3,837	$0.00	$0	0
2025-10-10	Dunlop A. Sinclair	—	Open-market sell S	Common Stock	31,092	$23.72	$737,536	3,837
2025-09-30	Dunlop A. Sinclair	—	Other disposed transaction J	Common Stock	3,837	$0.00	$0	30,142
2025-09-30	Dunlop A. Sinclair	—	Open-market sell S	Common Stock	31,092	$22.58	$702,057	33,979
2025-09-19	Dunlop A. Sinclair	—	Other disposed transaction J	Common Stock	3,837	$0.00	$0	65,071
2025-09-19	Dunlop A. Sinclair	—	Open-market sell S	Common Stock	31,092	$22.95	$713,561	68,908
2025-09-16	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,000	$24.34	$121,700	118,730
2025-09-15	Chopas James George	VP/Chief Accounting Officer	Open-market sell S	Common Stock	189	$24.19	$4,572	53,468
2025-09-10	Watson David O.	General Counsel	Open-market sell S	Common Stock	20,000	$26.17	$523,400	50,136
2025-09-08	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	15,000	$0.00	$0	242,903
2025-09-08	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	10,000	$27.83	$278,300	60,396
2025-09-08	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	32,729	$27.86	$911,830	110,936
2025-09-08	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M	Common Stock	15,000	$10.03	$150,450	143,665
2025-09-02	Chopas James George	VP/Chief Accounting Officer	Open-market sell S	Common Stock	548	$28.08	$15,386	53,657
2025-08-28	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	49,963	$28.39	$1,418,450	307,946
2025-08-27	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	175,037	$28.19	$4,934,293	357,909
2025-08-26	MELTZER LESLIE	Chief Research and Development	Equity grant / award A · derivative	Stock Option (Right to Buy)	92,592	$0.00	$0	92,592
2025-08-26	MELTZER LESLIE	Chief Research and Development	Equity grant / award A	Common Stock	61,804	$0.00	$0	61,804
2025-08-18	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,000	$27.80	$139,000	123,730
2025-07-17	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	8,997	$0.00	$0	100,538
2025-07-17	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	19,725	$20.21	$398,735	331,605
2025-07-17	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	8,997	$4.31	$38,777	351,330
2025-07-16	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,000	$19.55	$97,750	128,730
2025-07-15	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	800	$0.00	$0	109,535
2025-07-15	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	1,900	$20.09	$38,168	342,333
2025-07-15	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	800	$4.31	$3,448	344,233
2025-07-14	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	65,203	$0.00	$0	110,335
2025-07-14	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	137,465	$20.19	$2,774,923	343,433
2025-07-14	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	65,203	$4.31	$281,025	480,898
2025-06-24	Dunlop A. Sinclair	—	Other disposed transaction J	Common Stock	4,787	$0.00	$0	153,606
2025-06-18	Chopas James George	VP/Chief Accounting Officer	Equity grant / award A	Common Stock	6,250	$0.00	$0	54,205
2025-06-16	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,000	$18.77	$93,850	133,730
2025-06-09	Boucher Kelley	Chief People Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	67,396	$19.39	$1,306,808	67,396
2025-06-09	Boucher Kelley	Chief People Officer	Equity grant / award A	Common Stock	45,095	$0.00	$0	67,182
2025-05-28	Boucher Kelley	Chief People Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	32,976	$16.80	$553,997	32,976
2025-05-28	Boucher Kelley	Chief People Officer	Equity grant / award A	Common Stock	22,087	$0.00	$0	22,087
2025-05-21	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	12,780	$0.00	$0	0
2025-05-21	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	12,780	$3.76	$48,053	1,160,496
2025-04-17	WHEELER CRAIG A	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	28,195	$18.20	$513,149	28,195
2025-04-17	WHEELER CRAIG A	Dir	Equity grant / award A	Common Stock	16,483	$0.00	$0	16,483
2025-03-17	Chopas James George	VP/Chief Accounting Officer	Open-market sell S	Common Stock	183	$24.82	$4,543	47,955
2025-03-05	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,569	$25.10	$139,789	138,730
2025-03-04	Watson David O.	General Counsel	Equity grant / award G	Common Stock	6,667	$0.00	$0	10,000
2025-02-11	DeLong Mark Jeffrey	Chief Business & Strat Officer	Open-market sell S	Common Stock	363	$28.54	$10,360	83,945
2025-01-29	Watson David O.	General Counsel	Open-market sell S	Common Stock	695	$29.52	$20,519	144,299
2025-01-22	Watson David O.	General Counsel	Open-market sell S	Common Stock	3,323	$30.43	$101,104	144,994
2025-01-21	Watson David O.	General Counsel	Equity grant / award A	Common Stock	42,762	$0.00	$0	148,317
2025-01-17	Watson David O.	General Counsel	Open-market sell S	Common Stock	2,201	$29.96	$65,938	105,555
2025-01-13	Watson David O.	General Counsel	Open-market sell S	Common Stock	4,965	$28.70	$142,506	107,756
2025-01-08	Walbert Keli	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	15,388	$33.00	$507,804	15,388
2025-01-08	Walbert Keli	Dir	Equity grant / award A	Common Stock	9,090	$0.00	$0	9,090
2025-01-06	Baumal Caroline	Chief Medical Officer	Open-market sell S	Common Stock	2,816	$33.81	$95,215	55,560
2025-01-01	O'Brien Stephanie Monaghan	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	11,199	$0.00	$0	11,199
2025-01-01	O'Brien Stephanie Monaghan	Dir	Equity grant / award A	Common Stock	6,267	$0.00	$0	17,705
2024-12-31	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,054	$0.00	$0	84,946
2024-12-31	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,042	$0.00	$0	23,958
2024-12-31	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M	Common Stock	10,054	$13.85	$139,248	90,270
2024-12-31	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M	Common Stock	1,042	$14.95	$15,578	80,216
2024-12-23	Eisele Jeffrey	Chief Development Officer	Open-market sell S	Common Stock	63	$33.09	$2,085	57,145
2024-12-11	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,000	$34.23	$171,175	112,721
2024-11-01	Francois Cedric	Chief Executive Officer	Other disposed transaction J	Common Stock	182,146	$0.00	$0	472,065
2024-09-27	Watson David O.	General Counsel	Equity grant / award G	Common Stock	10,569	$0.00	$0	117,721
2024-09-23	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,600	$0.00	$0	0
2024-09-23	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	4,600	$13.19	$60,674	152,126
2024-09-16	Dunlop A. Sinclair	—	Open-market sell S	Common Stock	7,524	$36.79	$276,808	100,000
2024-09-16	Dunlop A. Sinclair	—	Open-market sell S	Common Stock	29,476	$36.09	$1,063,789	107,524
2024-09-03	Chopas James George	VP/Chief Accounting Officer	Open-market sell S	Common Stock	550	$39.49	$21,720	38,333
2024-08-12	DeLong Mark Jeffrey	Chief Business & Strat Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,201	$0.00	$0	14,799
2024-08-12	DeLong Mark Jeffrey	Chief Business & Strat Officer	Exercise / conversion M	Common Stock	5,201	$13.85	$72,034	60,395
2024-06-28	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	900	$0.00	$0	4,600
2024-06-28	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	900	$13.19	$11,871	134,418
2024-06-21	Dunlop A. Sinclair	—	Open-market sell S	Common Stock	1,695	$39.63	$67,173	136,998
2024-06-21	Dunlop A. Sinclair	—	Open-market sell S	Common Stock	35,305	$39.22	$1,384,662	138,693
2024-05-20	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	24,500	$0.00	$0	12,780
2024-05-20	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	24,500	$3.76	$92,120	1,140,483
2024-05-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	78,907	$0.00	$0	108,622
2024-05-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	100	$44.02	$4,402	1,115,983
2024-05-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	22,472	$42.85	$962,903	1,116,083
2024-05-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	56,335	$42.15	$2,374,543	1,138,555
2024-05-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	78,907	$4.31	$340,089	1,194,890
2024-04-18	Sullivan Timothy Eugene	Chief Financial Officer	Equity grant / award G	Common Stock	14,164	$0.00	$0	70,396
2024-04-12	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,500	$0.00	$0	5,500
2024-04-12	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	1,500	$13.19	$19,785	133,518
2024-04-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	69,107	$0.00	$0	37,280
2024-04-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	4,728	$54.92	$259,639	1,115,983
2024-04-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	64,379	$54.12	$3,483,966	1,120,711
2024-04-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	69,107	$3.76	$259,842	1,185,090
2024-04-01	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,000	$0.00	$0	257,903
2024-04-01	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	4,000	$58.66	$234,640	93,338
2024-04-01	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M	Common Stock	4,000	$10.03	$40,120	97,338
2024-03-19	Dunlop A. Sinclair	—	Open-market sell S	Common Stock	18,681	$57.18	$1,068,161	173,998
2024-03-18	DeLong Mark Jeffrey	Chief Business & Strat Officer	Open-market sell S	Common Stock	9,913	$56.90	$564,050	54,693
2024-03-15	Chopas James George	VP/Chief Accounting Officer	Open-market sell S	Common Stock	184	$56.46	$10,389	38,883
2024-03-13	Nicholson Nur	Chief Technical Officer	Open-market sell S	Common Stock	3,452	$58.13	$200,677	56,287
2024-03-13	Nicholson Nur	Chief Technical Officer	Open-market sell S	Common Stock	7,768	$57.31	$445,161	59,739
2024-03-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	69,107	$0.00	$0	106,387
2024-03-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	100	$63.35	$6,335	1,115,983
2024-03-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	26,257	$62.69	$1,646,041	1,116,083
2024-03-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	42,750	$61.88	$2,645,173	1,142,340
2024-03-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	69,107	$3.67	$253,623	1,185,090
2024-03-06	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,762	$0.00	$0	0
2024-03-06	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	3,762	$13.85	$52,104	107,152
2024-03-01	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	200,000	$0.00	$0	175,538
2024-03-01	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	50,000	$0.00	$0	8,840
2024-03-01	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	413	$65.68	$27,126	313,662
2024-03-01	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	116,512	$64.92	$7,563,528	314,075
2024-03-01	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	62,503	$64.26	$4,016,274	430,587
2024-03-01	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	41,704	$62.96	$2,625,813	493,090
2024-03-01	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	28,868	$62.21	$1,795,965	534,794
2024-03-01	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	200,000	$4.31	$862,000	563,662
2024-03-01	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	50,000	$3.76	$188,000	363,662
2024-02-12	Watson David O.	General Counsel	Open-market sell S	Common Stock	781	$67.77	$52,926	103,390
2024-01-29	Watson David O.	General Counsel	Open-market sell S	Common Stock	906	$64.14	$58,109	104,171
2024-01-23	Lewis Karen	Chief People Officer	Open-market sell S	Common Stock	4,286	$63.69	$272,975	47,637
2024-01-22	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	13,431	$65.00	$872,961	320,467
2024-01-17	Eisele Jeffrey	Chief Development Officer	Open-market sell S	Common Stock	5,207	$65.58	$341,475	67,443
2024-01-16	Deschatelets Pascal	Chief Scientific Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	9,805	$66.30	$650,072	9,805
2024-01-16	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	1,632	$66.81	$109,032	1,121,918
2024-01-16	Deschatelets Pascal	Chief Scientific Officer	Equity grant / award A	Common Stock	6,743	$0.00	$0	1,123,550
2024-01-04	Baumal Caroline	Chief Medical Officer	Open-market sell S	Common Stock	2,751	$60.05	$165,207	32,931
2024-01-01	FONTEYNE PAUL R.	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	5,748	$59.86	$344,075	5,748
2024-01-01	FONTEYNE PAUL R.	Dir	Equity grant / award A	Common Stock	3,341	$0.00	$0	16,438
2023-12-27	Eisele Jeffrey	Chief Development Officer	Open-market sell S	Common Stock	235	$60.23	$14,154	53,580
2023-12-26	Eisele Jeffrey	Chief Development Officer	Open-market sell S	Common Stock	68	$57.86	$3,935	53,815
2023-12-19	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,905	$0.00	$0	3,762
2023-12-19	Watson David O.	General Counsel	Open-market sell S	Common Stock	2,300	$57.38	$131,980	89,753
2023-12-19	Watson David O.	General Counsel	Open-market sell S	Common Stock	1,605	$57.00	$91,492	92,053
2023-12-19	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	7,905	$13.85	$109,484	93,658
2023-12-14	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,274	$0.00	$0	7,000
2023-12-14	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	6,274	$13.19	$82,754	128,677
2023-12-01	SCHEIBLER LUKAS	Chief Research Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	39,391
2023-12-01	SCHEIBLER LUKAS	Chief Research Officer	Open-market sell S	Common Stock	10,000	$60.00	$600,000	68,299
2023-12-01	SCHEIBLER LUKAS	Chief Research Officer	Exercise / conversion M	Common Stock	10,000	$13.85	$138,500	78,299
2023-11-30	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	14,158	$0.00	$0	267,903
2023-11-30	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	300	$54.79	$16,436	77,713
2023-11-30	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	13,858	$54.73	$758,448	78,013
2023-11-30	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M	Common Stock	14,158	$10.03	$142,005	91,871
2023-11-21	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	5,000	$48.80	$244,000	269,655
2023-11-17	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	8,894	$49.99	$444,620	122,403
2023-11-14	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	45,000	$0.00	$0	175,494
2023-11-14	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	45,000	$3.76	$169,200	1,116,807
2023-11-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	17,494	$0.00	$0	0
2023-11-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$47.27	$567,240	1,071,807
2023-11-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	17,494	$2.67	$46,709	1,083,807
2023-10-23	Chopas James George	VP/Chief Accounting Officer	Open-market sell S	Common Stock	132	$46.04	$6,077	32,680
2023-10-17	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	1,250
2023-10-17	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$48.50	$60,625	367,420
2023-10-17	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	368,670
2023-10-09	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	17,494
2023-10-09	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$40.38	$484,560	1,066,313
2023-10-09	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	1,078,313
2023-09-19	Francois Cedric	Chief Executive Officer	Equity grant / award G	Common Stock	150,000	$0.00	$0	804,211
2023-09-18	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	2,500
2023-09-18	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$45.00	$56,250	367,420
2023-09-18	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	368,670
2023-09-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	3,750
2023-09-15	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$45.34	$56,675	367,420
2023-09-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	368,670
2023-09-14	Chopas James George	VP/Chief Accounting Officer	Equity grant / award A	Common Stock	2,500	$0.00	$0	32,812
2023-09-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	35,994
2023-09-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$42.87	$514,440	1,059,813
2023-09-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	1,071,813
2023-09-06	SCHEIBLER LUKAS	Chief Research Officer	Open-market sell S	Common Stock	1,756	$43.01	$75,526	68,299
2023-09-01	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	300,000	$0.00	$0	0
2023-09-01	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	10,284	$42.44	$436,453	424,655
2023-09-01	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	139,716	$41.70	$5,826,506	434,939
2023-09-01	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	300,000	$2.67	$801,000	574,655
2023-08-31	Chopas James George	VP/Chief Accounting Officer	Open-market sell S	Common Stock	551	$41.23	$22,716	30,312
2023-08-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	54,494
2023-08-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$23.66	$283,920	1,053,313
2023-08-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	1,065,313
2023-07-21	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	49,779	$0.00	$0	5,000
2023-07-21	Machiels Alec	Dir	Exercise / conversion M	Common Stock	49,779	$2.67	$132,910	367,420
2023-07-20	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	50,000	$0.00	$0	54,779
2023-07-20	Machiels Alec	Dir	Exercise / conversion M	Common Stock	50,000	$2.67	$133,500	317,641
2023-07-17	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	104,779
2023-07-17	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$64.79	$80,988	267,641
2023-07-17	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	268,891
2023-07-10	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	72,994
2023-07-10	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$84.55	$1,014,600	1,046,813
2023-07-10	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	1,058,813
2023-07-03	Watson David O.	General Counsel	Open-market sell S	Common Stock	8,510	$89.98	$765,730	85,753
2023-06-28	Watson David O.	General Counsel	Equity grant / award G	Common Stock	12,750	$0.00	$0	80,705
2023-06-20	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	106,029
2023-06-20	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$88.41	$110,512	267,641
2023-06-20	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	268,891
2023-06-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	91,494
2023-06-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$91.35	$1,096,200	1,040,313
2023-06-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	1,052,313
2023-06-05	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	69,779	$0.00	$0	288,840
2023-06-05	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	30,506	$89.83	$2,740,229	77,713
2023-06-05	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	7,064	$88.36	$624,210	108,219
2023-06-05	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	30,609	$87.79	$2,687,121	115,283
2023-06-05	Sullivan Timothy Eugene	Chief Financial Officer	Open-market sell S	Common Stock	1,600	$90.60	$144,967	145,892
2023-06-05	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M	Common Stock	69,779	$10.03	$699,883	147,492
2023-06-01	Lewis Karen	Chief People Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	106,000
2023-06-01	Lewis Karen	Chief People Officer	Open-market sell S	Common Stock	5,000	$86.00	$430,000	41,504
2023-06-01	Lewis Karen	Chief People Officer	Exercise / conversion M	Common Stock	5,000	$34.11	$170,550	46,504
2023-05-24	Francois Cedric	Chief Executive Officer	Equity grant / award G	Common Stock	20,000	$0.00	$0	654,211
2023-05-17	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	20,000	$0.00	$0	300,000
2023-05-17	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	20,000	$2.67	$53,400	294,655
2023-05-17	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	107,279
2023-05-17	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$88.66	$110,825	267,641
2023-05-17	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	268,891
2023-05-16	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,000	$0.00	$0	320,000
2023-05-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	2,120	$87.67	$185,869	274,655
2023-05-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	7,528	$87.02	$655,059	276,775
2023-05-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	3,007	$85.90	$258,305	284,303
2023-05-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	14,611	$85.01	$1,242,065	287,310
2023-05-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	1,800	$83.84	$150,921	301,921
2023-05-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	934	$83.17	$77,682	303,721
2023-05-16	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	30,000	$2.67	$80,100	304,655
2023-05-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	109,994
2023-05-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$92.39	$1,108,680	1,033,813
2023-05-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	1,045,813
2023-05-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	282,500
2023-05-03	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	5,000	$82.71	$413,550	75,995
2023-05-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	5,000	$15.09	$75,450	80,995
2023-04-27	Francois Cedric	Chief Executive Officer	Equity grant / award G	Common Stock	382,946	$0.00	$0	382,946
2023-04-21	Watson David O.	General Counsel	Equity grant / award G	Common Stock	67,955	$0.00	$0	67,955
2023-04-19	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	20,000	$0.00	$0	350,000
2023-04-19	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	20,000	$2.67	$53,400	657,601
2023-04-19	Sullivan Timothy Eugene	Chief Financial Officer	Equity grant / award G	Common Stock	36,232	$0.00	$0	36,232
2023-04-18	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,000	$0.00	$0	370,000
2023-04-18	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	30,000	$82.02	$2,460,720	637,601
2023-04-18	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	30,000	$2.67	$80,100	667,601
2023-04-17	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	108,529
2023-04-17	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$81.05	$101,312	267,641
2023-04-17	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	268,891
2023-04-10	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	128,494
2023-04-10	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$78.21	$938,520	1,027,313
2023-04-10	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	1,039,313
2023-04-05	Francois Cedric	Chief Executive Officer	Equity grant / award G	Common Stock	26,990	$0.00	$0	634,211
2023-04-04	Francois Cedric	Chief Executive Officer	Equity grant / award G	Common Stock	380,000	$0.00	$0	607,221
2023-04-03	Francois Cedric	Chief Executive Officer	Equity grant / award G	Common Stock	227,221	$0.00	$0	227,221
2023-03-22	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,221	$0.00	$0	273,779
2023-03-22	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	100,000	$0.00	$0	58,840
2023-03-22	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	20,000	$0.00	$0	400,000
2023-03-22	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	7,221	$13.85	$100,011	1,271,812
2023-03-22	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	100,000	$3.76	$376,000	1,264,591
2023-03-22	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	20,000	$2.67	$53,400	1,164,591
2023-03-21	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,000	$0.00	$0	420,000
2023-03-21	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	30,000	$62.74	$1,882,332	1,144,591
2023-03-21	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	30,000	$2.67	$80,100	1,174,591
2023-03-17	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	109,779
2023-03-17	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$64.03	$80,038	267,641
2023-03-17	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	268,891
2023-03-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	146,994
2023-03-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$63.79	$765,480	1,020,813
2023-03-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	1,032,813
2023-03-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	292,500
2023-03-03	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	5,000	$63.84	$319,200	75,995
2023-03-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	5,000	$15.09	$75,450	80,995
2023-03-01	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	500	$65.33	$32,665	131,797
2023-02-27	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	100,000	$0.00	$0	158,840
2023-02-27	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	100,000	$3.76	$376,000	1,144,591
2023-02-23	Eisele Jeffrey	Chief Development Officer	Open-market sell S	Common Stock	1,646	$68.76	$113,179	53,883
2023-02-21	Lewis Karen	Chief People Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	9,402	$0.00	$0	9,402
2023-02-21	Lewis Karen	Chief People Officer	Other disposed transaction F	Common Stock	553	$58.50	$32,350	42,534
2023-02-21	Lewis Karen	Chief People Officer	Equity grant / award A	Common Stock	6,628	$0.00	$0	43,087
2023-02-17	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	111,029
2023-02-17	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$52.38	$65,475	267,641
2023-02-17	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	268,891
2023-02-10	Watson David O.	General Counsel	Other disposed transaction F	Common Stock	532	$51.21	$27,244	165,907
2023-02-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	165,494
2023-02-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$54.45	$653,400	1,006,756
2023-02-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	1,018,756
2023-02-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	297,500
2023-02-03	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	5,000	$55.85	$279,250	67,932
2023-02-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	5,000	$15.09	$75,450	72,932
2023-02-01	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	500	$52.61	$26,305	132,297
2023-01-30	Eisele Jeffrey	Chief Development Officer	Open-market sell S	Common Stock	883	$52.76	$46,587	46,468
2023-01-27	Watson David O.	General Counsel	Other disposed transaction F	Common Stock	551	$52.77	$29,076	166,439
2023-01-23	Lewis Karen	Chief People Officer	Open-market sell S	Common Stock	2,955	$51.58	$152,419	37,709
2023-01-20	Watson David O.	General Counsel	Other disposed transaction F	Common Stock	2,034	$52.05	$105,870	166,990
2023-01-17	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	112,279
2023-01-17	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$52.42	$65,525	267,641
2023-01-17	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	268,891
2023-01-12	Sullivan Timothy Eugene	Chief Financial Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	43,183	$52.66	$2,274,017	43,183
2023-01-12	Sullivan Timothy Eugene	Chief Financial Officer	Equity grant / award A	Common Stock	27,488	$0.00	$0	127,141
2023-01-12	Watson David O.	General Counsel	Equity grant / award A · derivative	Stock Option (Right to Buy)	37,708	$52.66	$1,985,703	37,708
2023-01-12	Watson David O.	General Counsel	Equity grant / award A	Common Stock	29,452	$0.00	$0	169,024
2023-01-12	Watson David O.	General Counsel	Equity grant / award A	Common Stock	24,003	$0.00	$0	139,572
2023-01-09	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	183,994
2023-01-09	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$46.08	$552,960	983,780
2023-01-09	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	995,780
2023-01-05	Grossi Federico	Chief Medical Officer	Open-market sell S	Common Stock	2,500	$48.79	$121,975	94,884
2023-01-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	302,500
2023-01-03	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	5,000	$50.70	$253,500	42,907
2023-01-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	5,000	$15.09	$75,450	47,907
2023-01-01	Machiels Alec	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	7,441	$0.00	$0	7,441
2023-01-01	Machiels Alec	Dir	Equity grant / award A	Common Stock	3,867	$0.00	$0	267,641
2022-12-29	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,000	$0.00	$0	220,494
2022-12-29	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	7,000	$3.67	$25,690	977,280
2022-12-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	113,529
2022-12-15	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$52.35	$65,438	263,774
2022-12-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	265,024
2022-12-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	202,494
2022-12-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$47.50	$570,000	970,280
2022-12-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	982,280
2022-12-05	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	307,500
2022-12-05	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	5,000	$50.38	$251,900	42,907
2022-12-05	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	5,000	$15.09	$75,450	47,907
2022-12-01	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	500	$49.93	$24,965	129,430
2022-11-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	114,779
2022-11-15	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$48.01	$60,012	263,774
2022-11-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	265,024
2022-11-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	220,994
2022-11-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$46.47	$557,640	963,780
2022-11-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	975,780
2022-11-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	312,500
2022-11-03	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	5,000	$58.54	$292,700	42,907
2022-11-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	5,000	$15.09	$75,450	47,907
2022-11-01	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	500	$60.83	$30,415	129,930
2022-10-26	Brown Victoria L.	Program Team Lead	Other disposed transaction F	Common Stock	130	$58.41	$7,593	24,844
2022-10-20	DeLong Mark Jeffrey	Senior Vice President	Other disposed transaction F	Common Stock	196	$58.00	$11,368	29,054
2022-10-14	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	116,029
2022-10-14	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$59.31	$74,138	263,774
2022-10-14	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	265,024
2022-10-10	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	239,494
2022-10-10	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$57.50	$690,000	957,280
2022-10-10	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	969,280
2022-10-03	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	2,500	$66.69	$166,725	102,384
2022-09-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	117,279
2022-09-15	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$66.00	$82,500	263,774
2022-09-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	265,024
2022-09-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,500	$0.00	$0	257,994
2022-09-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$63.98	$767,760	950,780
2022-09-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	18,500	$2.67	$49,395	962,780
2022-09-06	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	322,500
2022-09-06	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	5,000	$60.38	$301,900	42,907
2022-09-06	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	5,000	$15.09	$75,450	47,907
2022-09-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	2,500	$60.30	$150,750	104,884
2022-08-30	Chopas James George	VP/Chief Accounting Officer	Other disposed transaction F	Common Stock	558	$58.84	$32,833	18,581
2022-08-25	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,306	$0.00	$0	13,274
2022-08-25	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	4,306	$13.19	$56,796	130,430
2022-08-17	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	0
2022-08-17	DeLong Mark Jeffrey	Senior Vice President	Open-market sell S	Common Stock	5,000	$69.50	$347,500	29,250
2022-08-17	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M	Common Stock	5,000	$15.52	$77,600	34,250
2022-08-16	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	25,394	$0.00	$0	0
2022-08-16	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	25,394	$14.00	$355,516	126,124
2022-08-15	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	12,500	$0.00	$0	327,500
2022-08-15	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	12,500	$69.00	$862,500	42,907
2022-08-15	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	12,500	$15.09	$188,625	55,407
2022-08-11	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	12,500	$0.00	$0	340,000
2022-08-11	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	12,500	$67.00	$837,500	42,907
2022-08-11	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	12,500	$15.09	$188,625	55,407
2022-08-08	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	12,500	$0.00	$0	352,500
2022-08-08	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	12,500	$65.00	$812,500	42,907
2022-08-08	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	12,500	$15.09	$188,625	55,407
2022-08-04	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	15,000
2022-08-04	DeLong Mark Jeffrey	Senior Vice President	Open-market sell S	Common Stock	5,000	$62.00	$310,000	29,250
2022-08-04	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M	Common Stock	10,000	$15.52	$155,200	39,250
2022-08-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	365,000
2022-08-03	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	5,000	$15.09	$75,450	42,907
2022-08-03	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	5,000	$56.43	$282,150	37,907
2022-08-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	2,500	$55.99	$139,975	107,384
2022-07-27	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	25,000
2022-07-27	DeLong Mark Jeffrey	Senior Vice President	Open-market sell S	Common Stock	5,000	$57.00	$285,000	29,250
2022-07-27	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M	Common Stock	5,000	$15.52	$77,600	34,250
2022-07-21	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	9,606	$0.00	$0	25,394
2022-07-21	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	9,606	$14.00	$134,484	100,730
2022-07-19	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	30,000
2022-07-19	DeLong Mark Jeffrey	Senior Vice President	Open-market sell S	Common Stock	5,000	$56.42	$282,100	29,250
2022-07-19	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M	Common Stock	5,000	$15.52	$77,600	34,250
2022-07-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	119,779
2022-07-15	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$46.33	$57,912	263,774
2022-07-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	265,024
2022-07-11	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	370,000
2022-07-11	Townsend Adam J.	Chief Commercial Officer	Open-market sell S	Common Stock	5,000	$48.42	$242,100	42,907
2022-07-11	Townsend Adam J.	Chief Commercial Officer	Exercise / conversion M	Common Stock	5,000	$15.09	$75,450	47,907
2022-07-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,500	$0.00	$0	294,994
2022-07-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	12,000	$0.00	$0	301,494
2022-07-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$47.95	$575,400	937,780
2022-07-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	6,500	$2.67	$17,355	949,780
2022-07-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	12,000	$2.67	$32,040	943,280
2022-06-27	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	1,341	$46.79	$62,743	1,341
2022-06-23	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	15,000	$45.00	$675,000	285,679
2022-06-22	Watson David O.	General Counsel	Open-market sell S	Common Stock	10,000	$44.51	$445,140	115,569
2022-06-17	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	33,005	$0.00	$0	313,494
2022-06-17	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	33,005	$2.67	$88,123	931,280
2022-06-16	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	20,000
2022-06-16	DeLong Mark Jeffrey	Senior Vice President	Open-market sell S	Common Stock	10,000	$41.78	$417,850	29,250
2022-06-16	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M	Common Stock	10,000	$13.85	$138,500	39,250
2022-06-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	121,029
2022-06-15	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$39.29	$49,112	263,774
2022-06-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	265,024
2022-06-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,500	$0.00	$0	346,499
2022-06-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	12,000	$0.00	$0	352,999
2022-06-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	6,500	$2.67	$17,355	898,275
2022-06-08	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	12,000	$44.09	$529,080	891,775
2022-06-08	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	12,000	$2.67	$32,040	903,775
2022-06-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	2,500	$41.78	$104,450	109,561
2022-05-16	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	122,279
2022-05-16	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$39.18	$48,975	263,774
2022-05-16	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	265,024
2022-04-25	Sullivan Timothy Eugene	Chief Financial Officer	Other disposed transaction J · derivative	Stock Option (Right to Buy)	22,500	$0.00	$0	0
2022-04-25	Sullivan Timothy Eugene	Chief Financial Officer	Other disposed transaction J	Common Stock	3,750	$0.00	$0	99,653
2022-04-22	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	20,000	$0.00	$0	35,000
2022-04-22	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	20,000	$14.00	$280,000	91,124
2022-04-21	Townsend Adam J.	Chief Commercial Officer	Other disposed transaction J · derivative	Stock Option (Right to Buy)	11,250	$0.00	$0	0
2022-04-21	Townsend Adam J.	Chief Commercial Officer	Other disposed transaction J	Common Stock	1,875	$0.00	$0	42,138
2022-04-20	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,000	$0.00	$0	35,000
2022-04-20	DeLong Mark Jeffrey	Senior Vice President	Open-market sell S	Common Stock	7,000	$52.53	$367,710	28,481
2022-04-20	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M	Common Stock	7,000	$15.52	$108,640	35,481
2022-04-14	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	123,529
2022-04-14	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$50.90	$63,625	263,774
2022-04-14	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	265,024
2022-04-05	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	609	$0.00	$0	49,391
2022-04-05	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Open-market sell S	Common Stock	609	$60.09	$36,593	52,233
2022-04-05	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M	Common Stock	609	$13.85	$8,435	52,842
2022-04-04	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,504	$0.00	$0	50,000
2022-04-04	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Open-market sell S	Common Stock	1,249	$57.80	$72,198	52,233
2022-04-04	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Open-market sell S	Common Stock	1,437	$56.86	$81,714	53,482
2022-04-04	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Open-market sell S	Common Stock	818	$55.84	$45,677	54,919
2022-04-04	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M	Common Stock	3,504	$13.85	$48,530	55,737
2022-04-01	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	11,496	$0.00	$0	53,504
2022-04-01	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Open-market sell S	Common Stock	11,496	$55.05	$632,855	52,233
2022-04-01	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M	Common Stock	11,496	$13.85	$159,220	63,729
2022-03-25	Brown Victoria L.	Program Team Lead	Other disposed transaction F	Common Stock	82	$49.28	$4,041	28,325
2022-03-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock option (right to buy)	1,250	$0.00	$0	124,779
2022-03-15	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$39.57	$49,462	259,544
2022-03-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	260,794
2022-03-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	375	$43.53	$16,324	109,811
2022-02-23	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,100	$0.00	$0	57,723
2022-02-23	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	4,100	$4.31	$17,671	110,186
2022-02-15	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	375	$45.43	$17,036	106,086
2022-02-14	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,600	$0.00	$0	61,823
2022-02-14	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	3,600	$4.31	$15,516	106,461
2022-02-11	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Open-market sell S	Common Stock	1,666	$46.80	$77,969	51,513
2022-02-10	Watson David O.	General Counsel	Other disposed transaction F	Common Stock	491	$47.12	$23,136	132,444
2022-02-08	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	75,000
2022-02-08	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Open-market sell S	Common Stock	10,000	$45.00	$450,000	53,857
2022-02-08	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M	Common Stock	10,000	$13.85	$138,500	63,857
2022-02-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	375	$40.58	$15,218	103,566
2022-01-28	Brown Victoria L.	Program Team Lead	Other disposed transaction F	Common Stock	434	$38.59	$16,748	28,582
2022-01-21	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Equity grant / award A · derivative	Stock Option (Right to Buy)	36,951	$0.00	$0	36,951
2022-01-21	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Equity grant / award A	Common Stock	26,051	$0.00	$0	55,732
2022-01-21	Chopas James George	VP/Chief Accounting Officer	Equity grant / award A · derivative	Stock Option (right to buy)	15,116	$0.00	$0	15,116
2022-01-21	Chopas James George	VP/Chief Accounting Officer	Equity grant / award A	Common Stock	10,657	$0.00	$0	19,139
2022-01-14	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option(Right to Buy)	1,250	$0.00	$0	27,279
2022-01-14	Machiels Alec	Dir	Open-market sell S	Common Stock	1,250	$40.56	$50,700	673,774
2022-01-14	Machiels Alec	Dir	Exercise / conversion M	Common Stock	1,250	$2.67	$3,338	675,024
2022-01-12	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,500	$0.00	$0	68,823
2022-01-12	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,661	$0.00	$0	0
2022-01-12	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	1,500	$4.31	$6,465	75,515
2022-01-12	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	3,661	$3.76	$13,765	74,015
2022-01-03	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	375	$47.31	$17,741	70,354
2022-01-01	Chan Gerald	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	8,554	$0.00	$0	8,554
2022-01-01	Chan Gerald	Dir	Equity grant / award A	Common Stock	4,230	$0.00	$0	4,230
2021-12-27	Watson David O.	General Counsel	Open-market sell S	Common Stock	1,200	$48.50	$58,200	107,534
2021-12-22	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,397	$0.00	$0	14,888
2021-12-22	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,715	$0.00	$0	20,285
2021-12-22	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,826	$0.00	$0	11,667
2021-12-22	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,174	$0.00	$0	16,493
2021-12-22	Watson David O.	General Counsel	Open-market sell S	Common Stock	300	$48.58	$14,573	108,734
2021-12-22	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,097	$47.85	$243,917	109,034
2021-12-22	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	5,397	$14.95	$80,685	114,131
2021-12-22	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	4,715	$14.95	$70,489	108,734
2021-12-22	Watson David O.	General Counsel	Open-market sell S	Common Stock	5,174	$47.72	$246,883	104,019
2021-12-22	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	4,826	$13.85	$66,840	109,193
2021-12-22	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	5,174	$13.85	$71,660	104,367
2021-12-15	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	375	$42.88	$16,080	70,729
2021-12-08	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,000	$0.00	$0	3,661
2021-12-08	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	7,000	$3.76	$26,320	71,104
2021-12-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	375	$42.40	$15,900	64,104
2021-11-18	Morningside Venture Investments Ltd	10%	Open-market buy P	Common Stock	250,000	$40.00	$10,000,000	12,806,342
2021-11-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,000	$0.00	$0	131,529
2021-11-15	Machiels Alec	Dir	Open-market sell S	Common Stock	3,000	$43.50	$130,500	669,544
2021-11-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	3,000	$2.67	$8,010	672,544
2021-11-15	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	625	$43.50	$27,188	64,479
2021-11-04	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,000	$0.00	$0	134,529
2021-11-04	Machiels Alec	Dir	Open-market sell S	Common Stock	3,000	$35.00	$105,000	669,544
2021-11-04	Machiels Alec	Dir	Exercise / conversion M	Common Stock	3,000	$2.67	$8,010	672,544
2021-11-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	625	$30.70	$19,188	64,805
2021-10-26	Brown Victoria L.	Program Team Lead	Equity grant / award A	Common Stock	882	$0.00	$0	11,422
2021-10-20	Chopas James George	VP/Chief Accounting Officer	Equity grant / award A	Common Stock	882	$0.00	$0	8,482
2021-10-14	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	750	$34.57	$25,928	65,430
2021-10-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	750	$33.26	$24,945	66,180
2021-09-28	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,000	$0.00	$0	10,661
2021-09-28	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	4,000	$3.76	$15,040	66,930
2021-09-10	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,894	$0.00	$0	55,000
2021-09-10	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	6,894	$14.00	$96,516	66,894
2021-08-30	Chopas James George	See Remarks	Equity grant / award A · derivative	Stock Option (right to buy)	21,750	$0.00	$0	21,750
2021-08-30	Chopas James George	See Remarks	Equity grant / award A	Common Stock	7,600	$0.00	$0	7,600
2021-08-16	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$0.00	$0	137,529
2021-08-16	Machiels Alec	Dir	Open-market sell S	Common Stock	2,500	$56.95	$142,375	669,544
2021-08-16	Machiels Alec	Dir	Exercise / conversion M	Common Stock	2,500	$2.67	$6,675	672,044
2021-08-02	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	250	$63.99	$15,998	62,930
2021-07-21	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,000	$0.00	$0	42,000
2021-07-21	DeLong Mark Jeffrey	Senior Vice President	Open-market sell S	Common Stock	1,000	$65.00	$65,000	9,490
2021-07-21	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M	Common Stock	1,000	$15.52	$15,520	10,490
2021-07-15	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,000	$0.00	$0	43,000
2021-07-15	DeLong Mark Jeffrey	Senior Vice President	Open-market sell S	Common Stock	1,000	$62.30	$62,300	9,490
2021-07-15	DeLong Mark Jeffrey	Senior Vice President	Exercise / conversion M	Common Stock	1,000	$15.52	$15,520	10,490
2021-07-14	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	500	$64.68	$32,340	63,180
2021-07-08	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	250	$65.68	$16,420	63,680
2021-07-01	Perry Nicole D	Vice President - Accounting	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,000	$0.00	$0	7,161
2021-07-01	Perry Nicole D	Vice President - Accounting	Open-market sell S	Common Stock	1,000	$64.00	$64,000	4,847
2021-07-01	Perry Nicole D	Vice President - Accounting	Exercise / conversion M	Common Stock	1,000	$3.76	$3,760	5,847
2021-06-28	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	9,000	$0.00	$0	14,661
2021-06-28	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	9,000	$3.76	$33,840	63,930
2021-06-24	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,250	$0.00	$0	368,999
2021-06-24	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	6,250	$65.61	$410,062	869,587
2021-06-24	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	6,250	$2.67	$16,688	875,837
2021-06-21	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	489	$0.00	$0	954
2021-06-21	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	489	$4.31	$2,108	98,239
2021-06-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$0.00	$0	142,529
2021-06-15	Machiels Alec	Dir	Open-market sell S	Common Stock	2,500	$64.83	$162,075	669,544
2021-06-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	2,500	$2.67	$6,675	672,044
2021-06-14	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	500	$61.84	$30,920	54,930
2021-06-11	Perry Nicole D	Vice President - Accounting	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,000	$0.00	$0	34,161
2021-06-11	Perry Nicole D	Vice President - Accounting	Open-market sell S	Common Stock	1,000	$61.55	$61,555	4,847
2021-06-11	Perry Nicole D	Vice President - Accounting	Exercise / conversion M	Common Stock	1,000	$3.20	$3,200	5,847
2021-06-10	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Open-market sell S	Common Stock	3,417	$60.00	$205,020	26,651
2021-06-08	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	39,880	$0.00	$0	358,619
2021-06-08	Sullivan Timothy Eugene	Chief Financial Officer	Exercise / conversion M	Common Stock	39,880	$10.03	$399,996	74,141
2021-06-01	Dunlop A. Sinclair	Dir	Other acquired transaction J	Common Stock	2,682	$0.00	$0	303,361
2021-06-01	Dunlop A. Sinclair	Dir	Other acquired transaction J	Common Stock	13,108	$0.00	$0	73,108
2021-06-01	Dunlop A. Sinclair	Dir	Other disposed transaction J	Common Stock	31,855	$0.00	$0	0
2021-05-28	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	489	$0.00	$0	1,443
2021-05-28	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	489	$4.31	$2,108	97,750
2021-05-24	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,250	$0.00	$0	375,249
2021-05-24	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	6,250	$47.40	$296,250	869,587
2021-05-24	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	6,250	$2.67	$16,688	875,837
2021-05-20	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	5,773	$48.10	$277,681	31,855
2021-05-19	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	7,612	$50.00	$380,600	300,679
2021-05-18	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	800	$54.02	$43,216	308,291
2021-05-18	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	10,388	$53.50	$555,758	309,091
2021-05-18	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	1,200	$52.01	$62,412	319,479
2021-05-18	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	22,318	$54.57	$1,217,893	37,628
2021-05-18	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	36,387	$53.78	$1,956,893	59,946
2021-05-18	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	14,216	$52.63	$748,188	96,333
2021-05-18	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	64,179	$51.66	$3,315,487	110,549
2021-05-14	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	500	$45.39	$22,695	55,430
2021-05-03	Perry Nicole D	Vice President - Accounting	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,000	$0.00	$0	9,161
2021-05-03	Perry Nicole D	Vice President - Accounting	Open-market sell S	Common Stock	1,000	$50.73	$50,730	4,847
2021-05-03	Perry Nicole D	Vice President - Accounting	Exercise / conversion M	Common Stock	1,000	$3.76	$3,760	5,847
2021-04-30	Perry Nicole D	Vice President - Accounting	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,000	$0.00	$0	10,161
2021-04-30	Perry Nicole D	Vice President - Accounting	Open-market sell S	Common Stock	1,000	$50.00	$50,000	4,847
2021-04-30	Perry Nicole D	Vice President - Accounting	Exercise / conversion M	Common Stock	1,000	$3.76	$3,760	5,847
2021-04-28	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,500	$0.00	$0	381,499
2021-04-28	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	4,500	$2.67	$12,015	869,587
2021-04-23	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,250	$0.00	$0	385,999
2021-04-23	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	6,250	$46.13	$288,312	865,087
2021-04-23	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	6,250	$2.67	$16,688	871,337
2021-04-22	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	489	$0.00	$0	1,932
2021-04-22	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	489	$4.31	$2,108	97,261
2021-04-21	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$0.00	$0	147,529
2021-04-21	Machiels Alec	Dir	Open-market sell S	Common Stock	2,500	$45.76	$114,400	669,544
2021-04-21	Machiels Alec	Dir	Exercise / conversion M	Common Stock	2,500	$2.67	$6,675	672,044
2021-04-16	Dunlop A. Sinclair	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	50,000	$0.00	$0	71,894
2021-04-16	Dunlop A. Sinclair	Dir	Exercise / conversion M	Common Stock	50,000	$14.00	$700,000	50,000
2021-04-14	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	500	$42.82	$21,410	56,214
2021-04-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	600	$43.41	$26,046	56,714
2021-03-25	Brown Victoria L.	Program Team Lead	Other disposed transaction F	Common Stock	82	$41.16	$3,375	9,952
2021-03-22	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	978	$0.00	$0	2,421
2021-03-22	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	978	$4.31	$4,215	96,772
2021-03-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$0.00	$0	150,029
2021-03-15	Machiels Alec	Dir	Open-market sell S	Common Stock	2,500	$46.77	$116,925	669,544
2021-03-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	2,500	$2.67	$6,675	672,044
2021-03-10	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,250	$0.00	$0	392,249
2021-03-10	Deschatelets Pascal	Chief Scientific Officer	Open-market sell S	Common Stock	6,250	$50.74	$317,125	865,087
2021-03-10	Deschatelets Pascal	Chief Scientific Officer	Exercise / conversion M	Common Stock	6,250	$2.67	$16,688	871,337
2021-03-05	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,000	$0.00	$0	34,073
2021-03-05	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	5,000	$48.62	$243,075	57,814
2021-03-05	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	5,000	$3.20	$16,000	62,814
2021-03-01	Brown Victoria L.	Program Team Lead	Equity grant / award A · derivative	Stock Option (Right to Buy)	7,500	$0.00	$0	7,500
2021-03-01	Brown Victoria L.	Program Team Lead	Equity grant / award A	Common Stock	1,250	$0.00	$0	10,034
2021-02-16	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	500	$46.00	$23,000	58,414
2021-02-10	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Other disposed transaction F	Common Stock	680	$47.72	$32,450	29,290
2021-02-09	Perry Nicole D	Vice President - Accounting	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,000	$0.00	$0	13,161
2021-02-09	Perry Nicole D	Vice President - Accounting	Open-market sell S	Common Stock	2,000	$50.00	$100,000	2,500
2021-02-09	Perry Nicole D	Vice President - Accounting	Exercise / conversion M	Common Stock	2,000	$3.76	$7,520	4,500
2021-02-01	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	600	$44.00	$26,400	59,602
2021-01-28	Townsend Adam J.	Chief Commercial Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	11,250	$0.00	$0	11,250
2021-01-28	Townsend Adam J.	Chief Commercial Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	45,000	$0.00	$0	45,000
2021-01-28	Townsend Adam J.	Chief Commercial Officer	Equity grant / award A	Common Stock	1,875	$0.00	$0	19,553
2021-01-28	Townsend Adam J.	Chief Commercial Officer	Equity grant / award A	Common Stock	7,500	$0.00	$0	17,678
2021-01-27	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	31,992	$0.00	$0	389,948
2021-01-27	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	39,785	$0.00	$0	273,840
2021-01-27	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	31,992	$4.31	$137,886	1,184,856
2021-01-27	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	39,785	$3.76	$149,592	1,152,864
2021-01-25	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	11,500	$0.00	$0	23,661
2021-01-25	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,500	$0.00	$0	39,073
2021-01-25	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	11,500	$3.76	$43,240	50,827
2021-01-25	Grossi Federico	CHIEF MEDICAL OFFICER	Exercise / conversion M	Common Stock	3,500	$3.20	$11,200	39,327
2021-01-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$0.00	$0	155,029
2021-01-15	Machiels Alec	Dir	Open-market sell S	Common Stock	2,500	$53.15	$132,875	669,544
2021-01-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	2,500	$2.67	$6,675	672,044
2021-01-14	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	4,000	$51.99	$207,960	35,827
2021-01-04	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	600	$57.24	$34,344	39,827
2021-01-01	FONTEYNE PAUL R.	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	27,600	$0.00	$0	27,600
2020-12-23	Eisele Jeffrey	Exec VP, Program Team Lead	Equity grant / award A	Common Stock	1,211	$0.00	$0	1,211
2020-12-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$0.00	$0	157,529
2020-12-15	Machiels Alec	Dir	Open-market sell S	Common Stock	2,500	$52.16	$130,400	669,544
2020-12-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	2,500	$2.67	$6,675	672,044
2020-12-14	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	8,398	$0.00	$0	21,667
2020-12-14	Watson David O.	General Counsel	Open-market sell S	Common Stock	200	$55.91	$11,182	43,404
2020-12-14	Watson David O.	General Counsel	Open-market sell S	Common Stock	900	$55.00	$49,501	43,604
2020-12-14	Watson David O.	General Counsel	Open-market sell S	Common Stock	1,163	$52.73	$61,322	45,404
2020-12-14	Watson David O.	General Counsel	Open-market sell S	Common Stock	2,526	$51.32	$129,624	46,567
2020-12-14	Watson David O.	General Counsel	Open-market sell S	Common Stock	2,709	$50.61	$137,094	49,093
2020-12-14	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	8,398	$13.85	$116,312	51,802
2020-12-14	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	214	$56.25	$12,038	174,728
2020-12-14	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	17,132	$55.01	$942,431	174,942
2020-12-14	Dunlop A. Sinclair	Dir	Open-market sell S	Common Stock	7,654	$53.86	$412,244	192,074
2020-12-11	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	9,935	$0.00	$0	30,065
2020-12-11	Watson David O.	General Counsel	Open-market sell S	Common Stock	9,935	$50.00	$496,750	43,404
2020-12-11	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	9,935	$13.85	$137,600	53,339
2020-12-08	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,482	$0.00	$0	137,518
2020-12-08	SCHEIBLER LUKAS	CHIEF INNOVATION OFFICER	Exercise / conversion M	Common Stock	7,482	$26.73	$199,994	20,595
2020-12-04	Perry Nicole D	Vice President - Accounting	Exercise / conversion M · derivative	Stock Option (Right to Buy)	18,000	$0.00	$0	17,161
2020-12-04	Perry Nicole D	Vice President - Accounting	Open-market sell S	Common Stock	18,000	$50.00	$900,000	0
2020-12-04	Perry Nicole D	Vice President - Accounting	Exercise / conversion M	Common Stock	18,000	$3.76	$67,680	18,000
2020-12-01	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	40,000	$0.00	$0	313,625
2020-12-01	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	40,000	$3.76	$150,400	1,118,079
2020-11-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	5,000	$39.38	$196,900	1,078,079
2020-11-02	Grossi Federico	CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	600	$31.09	$18,654	27,725
2020-10-15	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$0.00	$0	162,529
2020-10-15	Machiels Alec	Dir	Open-market sell S	Common Stock	2,500	$35.00	$87,500	669,544
2020-10-15	Machiels Alec	Dir	Exercise / conversion M	Common Stock	2,500	$2.67	$6,675	672,044
2020-10-07	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,500	$0.00	$0	165,029
2020-10-07	Machiels Alec	Dir	Open-market sell S	Common Stock	7,500	$35.00	$262,500	669,544
2020-10-07	Machiels Alec	Dir	Exercise / conversion M	Common Stock	7,500	$2.67	$20,025	677,044
2020-10-01	Grossi Federico	See Remarks	Open-market sell S	Common Stock	600	$30.22	$18,132	28,325
2020-09-15	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	5,000	$30.96	$154,800	1,088,079
2020-09-01	Grossi Federico	See Remarks	Open-market sell S	Common Stock	600	$31.58	$18,948	28,925
2020-08-20	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	3,457	$30.00	$103,710	1,093,079
2020-08-18	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	1,543	$30.00	$46,290	1,096,536
2020-08-03	Grossi Federico	See Remarks	Open-market sell S	Common Stock	600	$26.28	$15,768	29,525
2020-07-15	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	5,000	$32.12	$160,600	1,098,079
2020-07-01	Grossi Federico	See Remarks	Open-market sell S	Common Stock	850	$32.43	$27,566	30,125
2020-06-15	Grossi Federico	See Remarks	Open-market sell S	Common Stock	856	$30.21	$25,860	30,975
2020-05-15	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	5,000	$29.92	$149,600	1,108,079
2020-05-08	FONTEYNE PAUL R.	Dir	Open-market buy P	Common Stock	5,000	$31.81	$159,034	5,000
2020-04-15	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	5,000	$29.77	$148,850	1,113,079
2020-04-02	FONTEYNE PAUL R.	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	37,500	$0.00	$0	37,500
2020-03-25	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$0.00	$0	180,029
2020-03-25	Machiels Alec	Dir	Open-market sell S	Common Stock	2,500	$30.00	$75,000	669,544
2020-03-25	Machiels Alec	Dir	Exercise / conversion M	Common Stock	2,500	$2.67	$6,675	672,044
2020-03-17	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,637	$0.00	$0	0
2020-03-17	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	30,637	$2.14	$65,563	1,083,704
2020-03-16	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,637	$0.00	$0	30,637
2020-03-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	300	$23.86	$7,158	1,053,067
2020-03-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	3,212	$22.28	$71,557	1,053,367
2020-03-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	15,065	$21.58	$325,088	1,056,579
2020-03-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	12,060	$20.69	$249,558	1,071,644
2020-03-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	700	$22.29	$15,600	1,083,704
2020-03-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	2,192	$21.57	$47,279	1,084,404
2020-03-16	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	2,108	$20.73	$43,695	1,086,596
2020-03-16	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	30,637	$2.14	$65,563	1,088,704
2020-03-10	Deschatelets Pascal	Chief Operating Officer	Equity grant / award G	Common Stock	161,656	$0.00	$0	847,025
2020-02-19	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,637	$0.00	$0	61,274
2020-02-19	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	30,637	$2.14	$65,563	1,058,067
2020-02-18	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,637	$0.00	$0	91,911
2020-02-18	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	5,000	$40.67	$203,330	1,027,430
2020-02-18	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	30,637	$40.66	$1,245,792	1,032,430
2020-02-18	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	30,637	$2.14	$65,563	1,063,067
2020-02-14	Machiels Alec	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$0.00	$0	182,529
2020-02-14	Machiels Alec	Dir	Open-market sell S	Common Stock	2,500	$42.35	$105,875	669,544
2020-02-14	Machiels Alec	Dir	Exercise / conversion M	Common Stock	2,500	$2.67	$6,675	672,044
2020-02-13	Deschatelets Pascal	Chief Operating Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	117,205	$0.00	$0	0
2020-02-13	Deschatelets Pascal	Chief Operating Officer	Open-market sell S	Common Stock	55,398	$40.98	$2,270,155	1,008,681
2020-02-13	Deschatelets Pascal	Chief Operating Officer	Exercise / conversion M	Common Stock	117,205	$2.14	$250,819	1,064,079
2020-02-12	Deschatelets Pascal	Chief Operating Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	117,206	$0.00	$0	117,205
2020-02-12	Deschatelets Pascal	Chief Operating Officer	Open-market sell S	Common Stock	52,075	$42.80	$2,228,966	946,874
2020-02-12	Deschatelets Pascal	Chief Operating Officer	Exercise / conversion M	Common Stock	117,206	$2.14	$250,821	998,949
2020-02-10	SCHEIBLER LUKAS	See Remarks	Equity grant / award A · derivative	Stock option (right to buy)	56,250	$0.00	$0	56,250
2020-02-10	SCHEIBLER LUKAS	See Remarks	Equity grant / award A	Common Stock	9,375	$0.00	$0	12,310
2020-01-27	Watson David O.	General Counsel	Exercise / conversion M · derivative	Stock Option (Right to Buy)	15,000	$0.00	$0	7,505
2020-01-27	Watson David O.	General Counsel	Exercise / conversion M	Common Stock	15,000	$2.67	$40,050	34,042
2020-01-27	Watson David O.	General Counsel	Open-market sell S	Common Stock	3,000	$40.47	$121,401	19,042
2020-01-16	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,637	$0.00	$0	122,548
2020-01-16	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	30,637	$2.14	$65,563	1,032,430
2020-01-15	Francois Cedric	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,638	$0.00	$0	153,185
2020-01-15	Francois Cedric	Chief Executive Officer	Exercise / conversion M	Common Stock	30,638	$2.14	$65,565	1,001,793
2020-01-15	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	5,000	$41.47	$207,350	1,001,793
2020-01-15	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	4,562	$42.55	$194,099	1,006,793
2020-01-15	Francois Cedric	Chief Executive Officer	Open-market sell S	Common Stock	26,076	$42.16	$1,099,338	1,011,355
2020-01-13	Morningside Venture Investments Ltd	10%	Open-market buy P	Common Stock	540,540	$37.00	$19,999,980	12,556,342

Regulatory Activity

Last 12 months to 2025-04-29

Insider Filings (Forms 3/4/5) — 12 months

Material Event Filings (8-K) — 12 months

8-K Material Event Filing Activity

Monthly count

Insider Trading Activity (Forms 3/4/5)

Monthly count