Financial Metrics

NTRA Natera, Inc.

Range: 2016-01-01 to 2026-04-29

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Financial Statements

Grouped by statement

Income Statement

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-03-31	-0.17	—	USD/shares	10-Q	2017-05-10
Quarterly	2016-06-30	-0.46	-170.6%	USD/shares	10-Q	2017-08-09
Quarterly	2016-09-30	-0.5	-8.7%	USD/shares	10-Q	2017-11-09
Quarterly	2017-03-31	-0.65	-30.0%	USD/shares	10-Q	2018-05-10
Quarterly	2017-06-30	-0.55	+15.4%	USD/shares	10-Q	2018-08-09
Quarterly	2017-09-30	-0.52	+5.5%	USD/shares	10-Q	2018-11-09
Quarterly	2018-03-31	-0.61	-17.3%	USD/shares	10-Q	2019-05-10
Quarterly	2018-06-30	-0.62	-1.6%	USD/shares	10-Q	2019-08-09
Quarterly	2018-09-30	-0.49	+21.0%	USD/shares	10-Q	2019-11-08
Quarterly	2019-03-31	-0.54	-10.2%	USD/shares	10-Q	2019-05-10
Quarterly	2019-06-30	-0.48	+11.1%	USD/shares	10-Q	2019-08-09
Quarterly	2019-09-30	-0.33	+31.2%	USD/shares	10-Q	2019-11-08
Quarterly	2021-03-31	-0.74	-124.2%	USD/shares	10-Q	2022-05-06
Quarterly	2021-06-30	-1.32	-78.4%	USD/shares	10-Q	2022-08-05
Quarterly	2021-09-30	-1.63	-23.5%	USD/shares	10-Q	2022-11-09
Quarterly	2022-03-31	-1.45	+11.0%	USD/shares	10-Q	2023-05-10
Quarterly	2022-06-30	-1.5	-3.4%	USD/shares	10-Q	2023-08-04
Quarterly	2022-09-30	-1.25	+16.7%	USD/shares	10-Q	2023-11-09
Quarterly	2023-03-31	-1.23	+1.6%	USD/shares	10-Q	2024-05-10
Quarterly	2023-06-30	-0.97	+21.1%	USD/shares	10-Q	2024-08-09
Quarterly	2023-09-30	-0.95	+2.1%	USD/shares	10-Q	2024-11-12
Quarterly	2024-03-31	-0.56	+41.1%	USD/shares	10-Q	2025-05-09
Quarterly	2024-06-30	-0.3	+46.4%	USD/shares	10-Q	2025-08-08
Quarterly	2024-09-30	-0.26	+13.3%	USD/shares	10-Q	2025-11-07
Quarterly	2025-03-31	-0.5	-92.3%	USD/shares	10-Q	2025-05-09
Quarterly	2025-06-30	-0.74	-48.0%	USD/shares	10-Q	2025-08-08
Quarterly	2025-09-30	-0.64	+13.5%	USD/shares	10-Q	2025-11-07
Annual	2016-12-31	-1.95	—	USD/shares	10-K	2019-03-15
Annual	2017-12-31	-2.59	-32.8%	USD/shares	10-K	2020-03-02
Annual	2018-12-31	-0.51	+80.3%	USD/shares	10-K	2020-03-02
Annual	2019-12-31	-1.79	-251.0%	USD/shares	10-K	2022-02-25
Annual	2020-12-31	-2.84	-58.7%	USD/shares	10-K	2023-03-01
Annual	2021-12-31	-5.21	-83.5%	USD/shares	10-K	2024-02-29
Annual	2022-12-31	-5.57	-6.9%	USD/shares	10-K	2025-02-28
Annual	2023-12-31	-3.78	+32.1%	USD/shares	10-K	2026-02-27
Annual	2024-12-31	-1.53	+59.5%	USD/shares	10-K	2026-02-27
Annual	2025-12-31	-1.52	+0.7%	USD/shares	10-K	2026-02-27

Balance Sheet

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Annual	2021-12-31	280394000.0	—	USD	10-K	2022-02-25
Annual	2022-12-31	281653000.0	+0.4%	USD	10-K	2024-02-29
Annual	2023-12-31	282945000.0	+0.5%	USD	10-K	2025-02-28

Cash Flow

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-03-31	3484000.0	—	USD	10-Q	2017-05-10
Quarterly	2016-06-30	7311000.0	+109.8%	USD	10-Q	2017-08-09
Quarterly	2016-09-30	14577000.0	+99.4%	USD	10-Q	2017-11-09
Quarterly	2017-03-31	6338000.0	-56.5%	USD	10-Q	2018-05-10
Quarterly	2017-06-30	8066000.0	+27.3%	USD	10-Q	2018-08-09
Quarterly	2017-09-30	9147000.0	+13.4%	USD	10-Q	2018-11-09
Quarterly	2018-03-31	852000.0	-90.7%	USD	10-Q	2019-05-10
Quarterly	2018-06-30	1227000.0	+44.0%	USD	10-Q	2019-08-09
Quarterly	2018-09-30	1770000.0	+44.3%	USD	10-Q	2019-11-08
Quarterly	2019-03-31	955000.0	-46.0%	USD	10-Q	2020-05-08
Quarterly	2019-06-30	1599000.0	+67.4%	USD	10-Q	2020-08-07
Quarterly	2019-09-30	2554000.0	+59.7%	USD	10-Q	2020-11-06
Quarterly	2020-03-31	7917000.0	+210.0%	USD	10-Q	2021-05-07
Quarterly	2020-06-30	10130000.0	+28.0%	USD	10-Q	2021-08-06
Quarterly	2020-09-30	12073000.0	+19.2%	USD	10-Q	2021-11-05
Quarterly	2021-03-31	10260000.0	-15.0%	USD	10-Q	2022-05-06
Quarterly	2021-06-30	18891000.0	+84.1%	USD	10-Q	2022-08-05
Quarterly	2021-09-30	32027000.0	+69.5%	USD	10-Q	2022-11-09
Quarterly	2022-03-31	15885000.0	-50.4%	USD	10-Q	2023-05-10
Quarterly	2022-06-30	23661000.0	+49.0%	USD	10-Q	2023-08-04
Quarterly	2022-09-30	35870000.0	+51.6%	USD	10-Q	2023-11-09
Quarterly	2023-03-31	11380000.0	-68.3%	USD	10-Q	2024-05-10
Quarterly	2023-06-30	20190000.0	+77.4%	USD	10-Q	2024-08-09
Quarterly	2023-09-30	29147000.0	+44.4%	USD	10-Q	2024-11-12
Quarterly	2024-03-31	20315000.0	-30.3%	USD	10-Q	2025-05-09
Quarterly	2024-06-30	31993000.0	+57.5%	USD	10-Q	2025-08-08
Quarterly	2024-09-30	48305000.0	+51.0%	USD	10-Q	2025-11-07
Quarterly	2025-03-31	21815000.0	-54.8%	USD	10-Q	2025-05-09
Quarterly	2025-06-30	47712000.0	+118.7%	USD	10-Q	2025-08-08
Quarterly	2025-09-30	70117000.0	+47.0%	USD	10-Q	2025-11-07
Annual	2016-12-31	23136000.0	—	USD	10-K	2019-03-15
Annual	2017-12-31	9867000.0	-57.4%	USD	10-K	2020-03-02
Annual	2018-12-31	3880000.0	-60.7%	USD	10-K	2021-02-26
Annual	2019-12-31	4968000.0	+28.0%	USD	10-K	2022-02-25
Annual	2020-12-31	19604000.0	+294.6%	USD	10-K	2023-03-01
Annual	2021-12-31	41030000.0	+109.3%	USD	10-K	2024-02-29
Annual	2022-12-31	47697000.0	+16.2%	USD	10-K	2025-02-28
Annual	2023-12-31	39199000.0	-17.8%	USD	10-K	2026-02-27
Annual	2024-12-31	66423000.0	+69.5%	USD	10-K	2026-02-27
Annual	2025-12-31	106188000.0	+59.9%	USD	10-K	2026-02-27

Share Data

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-03-31	50439000.0	—	shares	10-Q	2017-05-10
Quarterly	2016-06-30	51445000.0	+2.0%	shares	10-Q	2017-08-09
Quarterly	2016-09-30	52012000.0	+1.1%	shares	10-Q	2017-11-09
Quarterly	2017-03-31	53043000.0	+2.0%	shares	10-Q	2018-05-10
Quarterly	2017-06-30	53088000.0	+0.1%	shares	10-Q	2018-08-09
Quarterly	2017-09-30	53447000.0	+0.7%	shares	10-Q	2018-11-09
Quarterly	2018-03-31	54132000.0	+1.3%	shares	10-Q	2019-05-10
Quarterly	2018-06-30	54551000.0	+0.8%	shares	10-Q	2019-08-09
Quarterly	2018-09-30	60570000.0	+11.0%	shares	10-Q	2019-11-08
Quarterly	2019-03-31	62831000.0	+3.7%	shares	10-Q	2020-05-08
Quarterly	2019-06-30	68224000.0	+8.6%	shares	10-Q	2020-08-07
Quarterly	2019-09-30	70456000.0	+3.3%	shares	10-Q	2020-11-06
Quarterly	2020-03-31	78287000.0	+11.1%	shares	10-Q	2021-05-07
Quarterly	2020-06-30	79069000.0	+1.0%	shares	10-Q	2021-08-06
Quarterly	2020-09-30	80908000.0	+2.3%	shares	10-Q	2021-11-05
Quarterly	2021-03-31	86689000.0	+7.1%	shares	10-Q	2022-05-06
Quarterly	2021-06-30	88077000.0	+1.6%	shares	10-Q	2022-08-05
Quarterly	2021-09-30	92558000.0	+5.1%	shares	10-Q	2022-11-09
Quarterly	2022-03-31	95578000.0	+3.3%	shares	10-Q	2023-05-10
Quarterly	2022-06-30	96579000.0	+1.0%	shares	10-Q	2023-08-04
Quarterly	2022-09-30	97052000.0	+0.5%	shares	10-Q	2023-11-09
Quarterly	2023-03-31	111767000.0	+15.2%	shares	10-Q	2024-05-10
Quarterly	2023-06-30	113690000.0	+1.7%	shares	10-Q	2024-08-09
Quarterly	2023-09-30	115171000.0	+1.3%	shares	10-Q	2024-11-12
Quarterly	2024-03-31	120814000.0	+4.9%	shares	10-Q	2025-05-09
Quarterly	2024-06-30	122853000.0	+1.7%	shares	10-Q	2025-08-08
Quarterly	2024-09-30	123775000.0	+0.8%	shares	10-Q	2025-11-07
Quarterly	2025-03-31	134750000.0	+8.9%	shares	10-Q	2025-05-09
Quarterly	2025-06-30	136388000.0	+1.2%	shares	10-Q	2025-08-08
Quarterly	2025-09-30	137187000.0	+0.6%	shares	10-Q	2025-11-07
Annual	2016-12-31	51576000.0	—	shares	10-K	2019-03-15
Annual	2017-12-31	53604000.0	+3.9%	shares	10-K	2020-03-02
Annual	2018-12-31	57848000.0	+7.9%	shares	10-K	2021-02-26
Annual	2019-12-31	69555000.0	+20.2%	shares	10-K	2022-02-25
Annual	2020-12-31	81011000.0	+16.5%	shares	10-K	2023-03-01
Annual	2021-12-31	90558000.0	+11.8%	shares	10-K	2024-02-29
Annual	2022-12-31	98408000.0	+8.7%	shares	10-K	2025-02-28
Annual	2023-12-31	114997000.0	+16.9%	shares	10-K	2026-02-27
Annual	2024-12-31	124718000.0	+8.5%	shares	10-K	2026-02-27
Annual	2025-12-31	136721000.0	+9.6%	shares	10-K	2026-02-27

Credit and Bond Coverage

Company-level

Long-Term Debt (latest annual)

282,945,000

Total Liabilities (latest annual)

685,931,000

Current Liabilities (latest annual)

441,228,000

Metrics

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-03-31	-0.0478	—	ratio	10-Q	2017-05-10
Quarterly	2016-06-30	-0.1944	-306.4%	ratio	10-Q	2017-08-09
Quarterly	2016-09-30	-0.4123	-112.1%	ratio	10-Q	2017-11-09
Quarterly	2017-03-31	-0.4544	-10.2%	ratio	10-Q	2018-05-10
Quarterly	2017-06-30	-1.2286	-170.4%	ratio	10-Q	2018-08-09
Quarterly	2017-09-30	-2.9953	-143.8%	ratio	10-Q	2018-11-09
Quarterly	2018-03-31	8.4812	+383.1%	ratio	10-Q	2019-05-10
Quarterly	2018-06-30	3.0266	-64.3%	ratio	10-Q	2019-08-09
Quarterly	2018-09-30	-1.7025	-156.3%	ratio	10-Q	2019-11-08
Quarterly	2019-03-31	-6.8373	-301.6%	ratio	10-Q	2020-05-08
Quarterly	2019-06-30	-0.7145	+89.6%	ratio	10-Q	2020-08-07
Quarterly	2019-09-30	-1.0584	-48.1%	ratio	10-Q	2020-11-06
Quarterly	2020-03-31	-0.1366	+87.1%	ratio	10-Q	2021-05-07
Quarterly	2020-06-30	-0.3123	-128.6%	ratio	10-Q	2021-08-06
Quarterly	2020-09-30	-0.2861	+8.4%	ratio	10-Q	2021-11-05
Quarterly	2021-03-31	-0.1714	+40.1%	ratio	10-Q	2022-05-06
Quarterly	2021-06-30	-0.6014	-250.8%	ratio	10-Q	2022-08-05
Quarterly	2021-09-30	-0.4363	+27.5%	ratio	10-Q	2022-11-09
Quarterly	2022-03-31	-0.2556	+41.4%	ratio	10-Q	2023-05-10
Quarterly	2022-06-30	-0.6382	-149.7%	ratio	10-Q	2023-08-04
Quarterly	2022-09-30	-1.1206	-75.6%	ratio	10-Q	2023-11-09
Quarterly	2023-03-31	-0.2105	+81.2%	ratio	10-Q	2024-05-10
Quarterly	2023-06-30	-0.4156	-97.4%	ratio	10-Q	2024-08-09
Quarterly	2023-09-30	-0.4547	-9.4%	ratio	10-Q	2024-11-12
Quarterly	2024-03-31	-0.0851	+81.3%	ratio	10-Q	2025-05-09
Quarterly	2024-06-30	-0.1256	-47.5%	ratio	10-Q	2025-08-08
Quarterly	2024-09-30	-0.1556	-23.9%	ratio	10-Q	2025-11-07
Quarterly	2025-03-31	-0.0540	+65.3%	ratio	10-Q	2025-05-09
Quarterly	2025-06-30	-0.1347	-149.5%	ratio	10-Q	2025-08-08
Quarterly	2025-09-30	-0.2040	-51.4%	ratio	10-Q	2025-11-07
Annual	2016-12-31	-0.6988	—	ratio	10-K	2019-03-15
Annual	2017-12-31	-5.4148	-674.9%	ratio	10-K	2020-03-02
Annual	2018-12-31	-3.9846	+26.4%	ratio	10-K	2021-02-26
Annual	2019-12-31	-0.4479	+88.8%	ratio	10-K	2022-02-25
Annual	2020-12-31	-0.4725	-5.5%	ratio	10-K	2023-03-01
Annual	2021-12-31	-0.7220	-52.8%	ratio	10-K	2024-02-29
Annual	2022-12-31	-0.7762	-7.5%	ratio	10-K	2025-02-28
Annual	2023-12-31	-0.5681	+26.8%	ratio	10-K	2026-02-27
Annual	2024-12-31	-0.1593	+72.0%	ratio	10-K	2026-02-27
Annual	2025-12-31	-0.1216	+23.7%	ratio	10-K	2026-02-27

8-K Material Event Details

42 filings · 84 item records

This 8-K section tracks corporate event disclosures, not insider buy/sell sentiment. Insider trading direction is shown in the insider section below.

Event Type Distribution

Count per 8-K item

Insider Transaction History

1079 transaction records

Net Insider Flow

Monthly open-market buy value minus open-market sell value

Monthly Insider Activity Mix

Share volume split between open-market trades, grants, and exercises

Transaction Value Timeline

Each circle = one priced transaction; size ∝ value X-axis date:

All Transactions

Date	Insider	Title	Type	Security	Shares	Price	Total Value	Post-Tx Shares
2026-04-06	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	58,292	$0.00	$0	0
2026-04-06	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Other disposed transaction F	Common Stock	27,610	$204.87	$5,656,461	2,383,162
2026-04-06	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	58,292	$9.59	$559,020	2,410,772
2026-04-01	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,909	$205.00	$391,350	224,885
2026-04-01	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,200	$203.83	$244,591	226,794
2026-04-01	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	3,213	$203.07	$652,470	227,994
2026-04-01	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,778	$202.01	$359,167	231,207
2026-04-01	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	300	$200.79	$60,236	232,985
2026-03-31	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	41,708	$0.00	$0	58,292
2026-03-31	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	41,708	$9.59	$399,980	2,352,480
2026-03-20	Sheena Jonathan	—	Open-market sell S	Common Stock	280	$200.90	$56,253	21,032
2026-03-20	Sheena Jonathan	—	Open-market sell S	Common Stock	235	$199.88	$46,971	21,312
2026-03-20	Sheena Jonathan	—	Open-market sell S	Common Stock	371	$200.97	$74,561	21,032
2026-03-20	Sheena Jonathan	—	Open-market sell S	Common Stock	140	$199.82	$27,975	21,403
2026-03-20	Sheena Jonathan	—	Open-market sell S	Common Stock	239	$198.85	$47,526	21,543
2026-03-18	Sheena Jonathan	—	Open-market sell S	Common Stock	1,814	$198.65	$360,355	259,255
2026-03-18	Sheena Jonathan	—	Open-market sell S	Common Stock	956	$197.84	$189,135	261,069
2026-03-18	Sheena Jonathan	—	Open-market sell S	Common Stock	300	$196.27	$58,880	262,025
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	50,000	$0.00	$0	100,000
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	254	$198.02	$50,297	2,310,772
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	16,457	$197.22	$3,245,612	2,311,026
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	24,814	$196.23	$4,869,291	2,327,483
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	4,875	$195.42	$952,696	2,352,297
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	2,300	$194.17	$446,593	2,357,172
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	900	$192.43	$173,185	2,359,472
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	300	$190.68	$57,203	2,360,372
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	100	$190.07	$19,007	2,360,672
2026-03-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	50,000	$9.59	$479,500	2,360,772
2026-03-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	75,000	$0.00	$0	150,000
2026-03-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	1,100	$191.22	$210,345	2,310,772
2026-03-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	13,883	$190.46	$2,644,206	2,311,872
2026-03-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	21,504	$189.50	$4,075,006	2,325,755
2026-03-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	21,476	$188.54	$4,049,190	2,347,259
2026-03-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	17,037	$187.63	$3,196,632	2,368,735
2026-03-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	75,000	$9.59	$719,250	2,385,772
2026-03-13	Chapman Rowan E	—	Open-market sell S	Common Stock	122	$191.38	$23,348	5,752
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	75,000	$0.00	$0	225,000
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	100	$195.32	$19,532	2,310,772
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	4,082	$194.57	$794,218	2,310,872
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	7,043	$193.58	$1,363,389	2,314,954
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	8,579	$192.79	$1,653,957	2,321,997
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	9,896	$191.55	$1,895,595	2,330,576
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	22,063	$190.53	$4,203,721	2,340,472
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	2,886	$189.64	$547,307	2,362,535
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	6,451	$188.52	$1,216,112	2,365,421
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	5,809	$187.52	$1,089,300	2,371,872
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	8,091	$186.75	$1,510,989	2,377,681
2026-03-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	75,000	$9.59	$719,250	2,385,772
2026-03-10	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	785	$204.13	$160,244	63,354
2026-03-09	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Equity grant / award A	Common Stock	1,968	—	—	64,139
2026-03-06	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,598	$0.00	$0	0
2026-03-06	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,998	$198.04	$395,694	233,285
2026-03-06	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,500	$196.94	$295,406	235,283
2026-03-06	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,600	$195.80	$313,273	236,783
2026-03-06	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	2,900	$194.77	$564,832	238,383
2026-03-06	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	400	$193.73	$77,491	241,283
2026-03-06	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	5,598	$19.68	$110,169	241,683
2026-03-02	Sheena Jonathan	—	Open-market sell S	Common Stock	100	$202.85	$20,285	262,194
2026-03-02	Sheena Jonathan	—	Open-market sell S	Common Stock	2,400	$200.42	$481,012	262,394
2026-03-02	Sheena Jonathan	—	Open-market sell S	Common Stock	470	$198.50	$93,293	264,794
2026-02-27	Sheena Jonathan	—	Equity grant / award A	Common Stock	2,103	—	—	265,264
2026-02-03	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,639	$230.77	$378,229	137,847
2026-02-03	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	4,971	$227.45	$1,130,639	52,120
2026-02-03	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	700	$225.25	$157,674	57,091
2026-02-03	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,268	$230.77	$292,614	57,791
2026-02-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	16	$234.00	$3,744	139,486
2026-02-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	600	$233.24	$139,942	139,502
2026-02-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	850	$232.33	$197,477	140,102
2026-02-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	576	$230.84	$132,964	140,952
2026-02-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	878	$229.96	$201,903	141,528
2026-02-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	80	$228.50	$18,280	142,406
2026-01-30	Fesko John	PRESIDENT, CHIEF BUS. OFFICER	Equity grant / award A	Common Stock	6,135	—	—	181,675
2026-01-28	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	3,648	$237.66	$866,992	213,180
2026-01-27	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,322	$240.53	$558,514	216,828
2026-01-23	Sheena Jonathan	—	Open-market sell S	Common Stock	390	$244.87	$95,500	21,782
2026-01-23	Sheena Jonathan	—	Open-market sell S	Common Stock	200	$242.23	$48,446	22,332
2026-01-23	Sheena Jonathan	—	Open-market sell S	Common Stock	50	$245.62	$12,281	21,782
2026-01-23	Sheena Jonathan	—	Open-market sell S	Common Stock	355	$244.78	$86,897	21,832
2026-01-23	Sheena Jonathan	—	Open-market sell S	Common Stock	185	$243.49	$45,046	22,187
2026-01-23	Sheena Jonathan	—	Open-market sell S	Common Stock	160	$243.59	$38,974	22,172
2026-01-21	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,590	$235.00	$373,650	219,150
2026-01-20	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	3,386	$0.00	$0	0
2026-01-20	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,386	—	—	220,740
2026-01-20	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	71,932	$234.74	$16,885,203	217,354
2026-01-14	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Equity grant / award A	Common Stock	59,596	$0.00	$0	123,722
2026-01-05	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	39,615	$0.00	$0	0
2026-01-05	Sheena Jonathan	—	Exercise / conversion M	Common Stock	39,615	$9.59	$379,908	262,581
2026-01-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,659	$229.43	$380,620	123,499
2026-01-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,292	$228.33	$295,002	125,158
2025-12-19	Sheena Jonathan	—	Open-market sell S	Common Stock	550	$226.34	$124,489	22,532
2025-12-19	Sheena Jonathan	—	Open-market sell S	Common Stock	200	$224.74	$44,948	23,082
2025-12-17	Sheena Jonathan	—	Open-market sell S	Common Stock	130	$228.28	$29,677	222,966
2025-12-17	Sheena Jonathan	—	Open-market sell S	Common Stock	1,348	$227.44	$306,583	223,096
2025-12-17	Sheena Jonathan	—	Open-market sell S	Common Stock	1,592	$226.54	$360,652	224,444
2025-12-15	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award G	Common Stock	115	$0.00	$0	126,450
2025-12-15	Sheena Jonathan	—	Equity grant / award G	Common Stock	1,060	$0.00	$0	226,036
2025-12-12	ROSENMAN HERM	—	Open-market sell S	Common Stock	150	$229.09	$34,364	20,342
2025-12-12	ROSENMAN HERM	—	Open-market sell S	Common Stock	11,987	$228.49	$2,738,859	20,492
2025-12-12	ROSENMAN HERM	—	Open-market sell S	Common Stock	21,910	$227.35	$4,981,309	32,479
2025-12-12	ROSENMAN HERM	—	Open-market sell S	Common Stock	14,372	$226.62	$3,256,945	54,389
2025-12-12	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Exercise / conversion M	Common Stock	13,500	$9.59	$129,465	126,565
2025-12-12	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	4,692	$230.76	$1,082,714	113,065
2025-12-12	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Exercise / conversion M	Common Stock	8,876	$9.59	$85,121	117,757
2025-12-12	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award G	Common Stock	180	$0.00	$0	108,881
2025-12-10	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Exercise / conversion M · derivative	Stock Option (right to buy)	22,376	$0.00	$0	5,125
2025-12-09	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	4,436	$0.00	$0	5,544
2025-12-09	Sheena Jonathan	—	Exercise / conversion M	Common Stock	4,436	$9.29	$41,210	227,096
2025-12-05	Chapman Rowan E	—	Exercise / conversion M · derivative	Stock Option (right to buy)	4,000	$0.00	$0	7,000
2025-12-05	Chapman Rowan E	—	Open-market sell S	Common Stock	366	$243.39	$89,081	5,777
2025-12-05	Chapman Rowan E	—	Open-market sell S	Common Stock	4,000	$243.08	$972,308	6,143
2025-12-05	Chapman Rowan E	—	Exercise / conversion M	Common Stock	4,000	$32.15	$128,600	10,143
2025-12-04	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,902	$0.00	$0	5,598
2025-12-04	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	6,902	$19.68	$135,831	208,601
2025-12-01	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	474	$239.53	$113,535	109,061
2025-12-01	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,527	$238.24	$363,797	109,535
2025-12-01	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	250	$237.77	$59,443	111,062
2025-12-01	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	749	$237.23	$177,683	111,312
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	500	$239.11	$119,555	1,154,198
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	18,839	$238.57	$4,494,418	1,154,698
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	15,336	$237.69	$3,645,260	1,173,537
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	6,173	$236.54	$1,460,149	1,188,873
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	9,623	$235.65	$2,267,672	1,195,046
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	9,991	$234.55	$2,343,401	1,204,669
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	7,032	$233.66	$1,643,098	1,214,660
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	3,606	$232.75	$839,308	1,221,692
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	900	$231.23	$208,110	1,225,298
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	1,000	$230.03	$230,030	1,226,198
2025-11-24	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	2,000	$228.97	$457,934	1,227,198
2025-11-21	Sheena Jonathan	—	Open-market sell S	Common Stock	2,000	$230.01	$460,011	23,282
2025-11-20	Baynes Roy D.	—	Exercise / conversion M · derivative	Stock Option (right to buy)	7,068	$0.00	$0	0
2025-11-20	Baynes Roy D.	—	Exercise / conversion M · derivative	Stock Option (right to buy)	600	$0.00	$0	0
2025-11-20	Baynes Roy D.	—	Open-market sell S	Common Stock	1,884	$224.89	$423,685	18,359
2025-11-20	Baynes Roy D.	—	Open-market sell S	Common Stock	1,900	$223.90	$425,417	20,243
2025-11-20	Baynes Roy D.	—	Open-market sell S	Common Stock	1,800	$222.90	$401,220	22,143
2025-11-20	Baynes Roy D.	—	Open-market sell S	Common Stock	900	$221.81	$199,632	23,943
2025-11-20	Baynes Roy D.	—	Open-market sell S	Common Stock	1,184	$220.14	$260,646	24,843
2025-11-20	Baynes Roy D.	—	Exercise / conversion M	Common Stock	7,068	$41.19	$291,131	26,027
2025-11-20	Baynes Roy D.	—	Exercise / conversion M	Common Stock	600	$40.93	$24,558	18,959
2025-11-20	Sheena Jonathan	—	Open-market sell S	Common Stock	10,000	$225.08	$2,250,816	222,660
2025-11-19	Baynes Roy D.	—	Exercise / conversion M · derivative	Stock Option (right to buy)	5,112	$0.00	$0	600
2025-11-19	Baynes Roy D.	—	Open-market sell S	Common Stock	2,135	$216.07	$461,304	18,359
2025-11-19	Baynes Roy D.	—	Open-market sell S	Common Stock	1,727	$214.79	$370,946	20,494
2025-11-19	Baynes Roy D.	—	Open-market sell S	Common Stock	1,250	$213.47	$266,839	22,221
2025-11-19	Baynes Roy D.	—	Exercise / conversion M	Common Stock	5,112	$40.93	$209,234	23,471
2025-11-11	Sheena Jonathan	—	Open-market sell S	Common Stock	170	$209.28	$35,578	25,282
2025-11-11	Sheena Jonathan	—	Open-market sell S	Common Stock	390	$207.94	$81,097	25,452
2025-11-11	Sheena Jonathan	—	Open-market sell S	Common Stock	190	$206.86	$39,304	25,842
2025-11-11	Sheena Jonathan	—	Open-market sell S	Common Stock	163	$209.28	$34,113	25,282
2025-11-11	Sheena Jonathan	—	Open-market sell S	Common Stock	382	$207.95	$79,435	25,445
2025-11-11	Sheena Jonathan	—	Open-market sell S	Common Stock	205	$206.86	$42,407	25,827
2025-11-07	Sheena Jonathan	—	Open-market sell S	Common Stock	100	$198.38	$19,838	232,660
2025-11-07	Sheena Jonathan	—	Open-market sell S	Common Stock	600	$196.06	$117,633	232,860
2025-11-07	Sheena Jonathan	—	Open-market sell S	Common Stock	300	$193.59	$58,078	233,460
2025-11-07	Sheena Jonathan	—	Open-market sell S	Common Stock	400	$192.64	$77,055	233,760
2025-11-07	Sheena Jonathan	—	Open-market sell S	Common Stock	90	$191.04	$17,193	234,160
2025-11-07	Sheena Jonathan	—	Open-market sell S	Common Stock	1,480	$190.33	$281,685	234,250
2025-11-04	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	5,702	$201.18	$1,147,109	2,280,852
2025-11-04	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	17,198	$200.29	$3,444,565	2,286,554
2025-11-03	Sheena Jonathan	—	Open-market sell S	Common Stock	2,000	$200.00	$400,000	26,032
2025-10-31	ROSENMAN HERM	—	Equity grant / award A	Common Stock	132	—	—	68,761
2025-10-28	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	3,680	$191.46	$704,580	149,840
2025-10-27	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,335	$192.32	$449,077	153,520
2025-10-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	755	$196.77	$148,561	69,189
2025-10-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	495	$187.16	$92,644	69,944
2025-10-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,250	$0.00	$0	0
2025-10-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,250	—	—	70,439
2025-10-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	920	$186.68	$171,746	69,189
2025-10-21	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	292	$187.95	$54,881	117,267
2025-10-20	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	10,000	$190.00	$1,900,000	5,000
2025-10-17	Sheena Jonathan	—	Open-market sell S	Common Stock	337	$179.29	$60,421	28,032
2025-10-17	Sheena Jonathan	—	Open-market sell S	Common Stock	413	$178.58	$73,754	28,369
2025-10-17	Sheena Jonathan	—	Open-market sell S	Common Stock	275	$179.35	$49,322	28,032
2025-10-17	Sheena Jonathan	—	Open-market sell S	Common Stock	475	$178.66	$84,864	28,307
2025-10-15	Sheena Jonathan	—	Open-market sell S	Common Stock	423	$176.63	$74,712	236,112
2025-10-15	Sheena Jonathan	—	Open-market sell S	Common Stock	988	$175.90	$173,786	236,535
2025-10-15	Sheena Jonathan	—	Open-market sell S	Common Stock	1,506	$175.11	$263,715	237,523
2025-10-15	Sheena Jonathan	—	Open-market sell S	Common Stock	153	$172.99	$26,468	239,029
2025-10-01	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	780	$160.70	$125,347	117,559
2025-10-01	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,816	$159.91	$290,402	118,339
2025-10-01	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	404	$158.96	$64,220	120,155
2025-09-30	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,364	$162.05	$221,040	203,300
2025-09-29	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	2,500	$0.00	$0	0
2025-09-29	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	2,500	—	—	204,664
2025-09-19	Sheena Jonathan	—	Open-market sell S	Common Stock	380	$180.68	$68,659	28,782
2025-09-19	Sheena Jonathan	—	Open-market sell S	Common Stock	1,518	$180.06	$273,329	29,162
2025-09-19	Sheena Jonathan	—	Open-market sell S	Common Stock	3,602	$179.09	$645,093	30,680
2025-09-19	Sheena Jonathan	—	Open-market sell S	Common Stock	676	$180.68	$122,138	28,782
2025-09-19	Sheena Jonathan	—	Open-market sell S	Common Stock	1,380	$179.88	$248,240	29,458
2025-09-19	Sheena Jonathan	—	Open-market sell S	Common Stock	3,444	$179.08	$616,748	30,838
2025-09-19	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	1,188	$181.28	$215,363	2,320,852
2025-09-19	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	24,339	$180.54	$4,394,236	2,322,040
2025-09-18	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	14,473	$180.13	$2,607,069	2,346,379
2025-09-18	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	10,000	$180.00	$1,800,000	15,000
2025-09-17	Sheena Jonathan	—	Open-market sell S	Common Stock	256	$176.61	$45,212	239,182
2025-09-17	Sheena Jonathan	—	Open-market sell S	Common Stock	2,814	$175.88	$494,936	239,438
2025-09-15	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award G	Common Stock	300	$0.00	$0	120,559
2025-09-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	500	$172.64	$86,320	25,000
2025-09-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	4,500	$170.31	$766,387	25,500
2025-09-02	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,907	$167.69	$319,779	158,514
2025-09-02	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,472	$166.29	$244,773	160,421
2025-09-02	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,700	$165.44	$281,243	161,893
2025-08-28	Chapman Rowan E	—	Open-market sell S	Common Stock	2,750	$166.99	$459,222	6,015
2025-08-14	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	8	$155.42	$1,243	123,859
2025-08-14	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	867	$155.46	$134,784	123,867
2025-08-12	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award A	Common Stock	1,675	—	—	124,734
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	20	$156.32	$3,126	34,282
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	610	$155.74	$95,003	34,302
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	270	$154.04	$41,592	34,912
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	180	$152.40	$27,432	35,182
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	300	$151.12	$45,337	35,362
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	120	$149.56	$17,948	35,662
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	639	$155.80	$99,553	34,282
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	191	$154.60	$29,528	34,921
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	200	$152.73	$30,546	35,112
2025-08-11	Sheena Jonathan	—	Open-market sell S	Common Stock	470	$150.95	$70,948	35,312
2025-08-08	Sheena Jonathan	—	Open-market sell S	Common Stock	200	$164.51	$32,902	242,252
2025-08-08	Sheena Jonathan	—	Open-market sell S	Common Stock	800	$163.88	$131,107	242,452
2025-08-08	Sheena Jonathan	—	Open-market sell S	Common Stock	1,030	$162.73	$167,616	243,252
2025-08-08	Sheena Jonathan	—	Open-market sell S	Common Stock	639	$159.68	$102,033	244,282
2025-08-08	Sheena Jonathan	—	Open-market sell S	Common Stock	301	$158.63	$47,748	244,921
2025-08-08	Sheena Jonathan	—	Open-market sell S	Common Stock	100	$156.40	$15,640	245,222
2025-08-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,997	$133.31	$399,538	163,593
2025-08-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,810	$132.43	$372,118	166,590
2025-07-28	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	6,092	$139.81	$851,712	169,400
2025-07-25	Chapman Rowan E	—	Equity grant / award A	Common Stock	149	—	—	8,765
2025-07-25	Williams Brinkley Ruth	—	Equity grant / award A	Common Stock	112	—	—	5,219
2025-07-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	297	$139.95	$41,565	70,494
2025-07-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	458	$139.20	$63,755	70,791
2025-07-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	495	$141.28	$69,934	71,249
2025-07-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,250	$0.00	$0	1,250
2025-07-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,250	—	—	71,744
2025-07-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	920	$139.58	$128,415	70,494
2025-07-21	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	291	$139.29	$40,533	128,265
2025-07-21	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	464	$139.29	$64,631	204,158
2025-07-21	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	602	$139.29	$83,853	71,414
2025-07-20	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	856	$0.00	$0	1,712
2025-07-20	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	856	—	—	204,622
2025-07-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,522	$0.00	$0	3,044
2025-07-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,522	—	—	72,016
2025-07-16	Sheena Jonathan	—	Open-market sell S	Common Stock	3,070	$149.96	$460,388	245,704
2025-07-02	Sheena Jonathan	—	Open-market sell S	Common Stock	189	$161.29	$30,483	35,782
2025-07-02	Sheena Jonathan	—	Open-market sell S	Common Stock	1,011	$160.11	$161,869	35,971
2025-07-02	Sheena Jonathan	—	Open-market sell S	Common Stock	300	$159.14	$47,742	36,982
2025-07-02	Sheena Jonathan	—	Open-market sell S	Common Stock	208	$161.23	$33,535	35,782
2025-07-02	Sheena Jonathan	—	Open-market sell S	Common Stock	1,092	$160.10	$174,835	35,990
2025-07-02	Sheena Jonathan	—	Open-market sell S	Common Stock	200	$159.22	$31,845	37,082
2025-07-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	648	$167.77	$108,714	173,728
2025-07-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stck	3,187	$167.19	$532,839	174,376
2025-07-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	500	$165.83	$82,917	177,563
2025-07-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,008	$164.00	$165,308	178,063
2025-06-27	Chapman Rowan E	—	Equity grant / award A	Common Stock	271	—	—	8,616
2025-06-27	Chapman Rowan E	—	Equity grant / award A	Common Stock	2,143	—	—	8,345
2025-06-20	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	2,278	$171.50	$390,671	203,766
2025-06-20	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	7,630	$170.63	$1,301,911	206,044
2025-06-18	Sheena Jonathan	—	Open-market sell S	Common Stock	3,070	$167.29	$513,571	248,774
2025-06-18	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	10,000	$170.18	$1,701,795	213,674
2025-06-16	Sheena Jonathan	—	Open-market sell S	Common Stock	699	$165.41	$115,620	37,282
2025-06-16	Sheena Jonathan	—	Open-market sell S	Common Stock	425	$164.64	$69,972	37,981
2025-06-16	Sheena Jonathan	—	Open-market sell S	Common Stock	176	$162.52	$28,603	38,606
2025-06-16	Sheena Jonathan	—	Open-market sell S	Common Stock	547	$165.48	$90,519	37,282
2025-06-16	Sheena Jonathan	—	Open-market sell S	Common Stock	550	$164.81	$90,644	37,829
2025-06-16	Sheena Jonathan	—	Open-market sell S	Common Stock	203	$163.41	$33,172	38,379
2025-06-16	Sheena Jonathan	—	Open-market sell S	Common Stock	200	$163.10	$32,620	38,406
2025-06-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	5,000	$165.85	$829,250	30,000
2025-06-10	Marcus Gail Boxer	—	Open-market sell S	Common Stock	600	$165.04	$99,027	5,704
2025-06-10	Marcus Gail Boxer	—	Open-market sell S	Common Stock	3,400	$164.33	$558,734	6,304
2025-06-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	100	$159.12	$15,912	133,205
2025-06-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	465	$158.37	$73,643	133,305
2025-06-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,145	$157.23	$180,028	133,770
2025-06-02	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,290	$156.30	$201,629	134,915
2025-05-28	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	10,000	$161.00	$1,610,000	35,000
2025-05-27	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,649	$156.85	$258,646	128,556
2025-05-20	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	10,000	$153.90	$1,539,000	45,000
2025-05-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	9,000	$153.10	$1,377,900	55,000
2025-05-16	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	10,000	$152.60	$1,526,000	64,000
2025-05-15	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	10,000	$150.20	$1,502,000	74,000
2025-05-12	Sheena Jonathan	—	Open-market sell S	Common Stock	708	$159.01	$112,577	38,782
2025-05-12	Sheena Jonathan	—	Open-market sell S	Common Stock	383	$158.01	$60,517	39,490
2025-05-12	Sheena Jonathan	—	Open-market sell S	Common Stock	409	$157.08	$64,248	39,873
2025-05-12	Sheena Jonathan	—	Open-market sell S	Common Stock	100	$159.77	$15,977	38,782
2025-05-12	Sheena Jonathan	—	Open-market sell S	Common Stock	690	$159.06	$109,749	38,882
2025-05-12	Sheena Jonathan	—	Open-market sell S	Common Stock	307	$157.88	$48,469	39,572
2025-05-12	Sheena Jonathan	—	Open-market sell S	Common Stock	403	$156.90	$63,229	39,879
2025-05-09	Sheena Jonathan	—	Open-market sell S	Common Stock	100	$164.03	$16,403	251,844
2025-05-09	Sheena Jonathan	—	Open-market sell S	Common Stock	400	$163.07	$65,229	251,944
2025-05-09	Sheena Jonathan	—	Open-market sell S	Common Stock	1,231	$162.31	$199,800	252,344
2025-05-09	Sheena Jonathan	—	Open-market sell S	Common Stock	600	$159.76	$95,859	253,575
2025-05-09	Sheena Jonathan	—	Open-market sell S	Common Stock	107	$158.02	$16,908	254,175
2025-05-09	Sheena Jonathan	—	Open-market sell S	Common Stock	240	$155.50	$37,320	254,282
2025-05-09	Sheena Jonathan	—	Open-market sell S	Common Stock	392	$153.95	$60,348	254,522
2025-05-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	770	$152.04	$117,071	185,182
2025-05-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,186	$151.26	$330,665	185,952
2025-05-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,015	$149.94	$302,130	188,138
2025-05-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,009	$148.25	$297,837	190,153
2025-04-28	Sheena Jonathan	—	Open-market sell S	Common Stock	439	$152.18	$66,808	254,914
2025-04-25	ROSENMAN HERM	—	Equity grant / award A	Common Stock	164	—	—	66,062
2025-04-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	194	$152.46	$29,577	75,557
2025-04-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	561	$152.45	$85,524	75,751
2025-04-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	495	$150.74	$74,616	76,312
2025-04-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,250	$0.00	$0	2,500
2025-04-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,250	—	—	76,807
2025-04-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	603	$145.35	$87,645	75,557
2025-04-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	308	$144.30	$44,446	76,160
2025-04-21	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	8	$146.16	$1,169	76,468
2025-04-21	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	602	$145.54	$87,615	76,476
2025-04-21	Fesko John	PRESIDENT, CHIEF BUS. OFFICER	Open-market sell S	Common Stock	4	$146.10	$584	156,946
2025-04-21	Fesko John	PRESIDENT, CHIEF BUS. OFFICER	Open-market sell S	Common Stock	339	$145.54	$49,338	156,950
2025-04-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,521	$0.00	$0	4,566
2025-04-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,521	—	—	77,078
2025-04-04	Sheena Jonathan	—	Open-market sell S	Common Stock	100	$136.05	$13,605	255,249
2025-04-04	Sheena Jonathan	—	Open-market sell S	Common Stock	300	$135.24	$40,573	255,349
2025-04-04	Sheena Jonathan	—	Open-market sell S	Common Stock	400	$133.86	$53,544	255,649
2025-04-04	Sheena Jonathan	—	Open-market sell S	Common Stock	1,050	$133.28	$139,939	256,049
2025-04-04	Sheena Jonathan	—	Open-market sell S	Common Stock	1,220	$132.04	$161,091	257,099
2025-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	355	$140.94	$50,034	40,282
2025-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	395	$140.00	$55,301	40,637
2025-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	490	$138.55	$67,889	41,032
2025-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	260	$137.08	$35,641	41,522
2025-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	100	$141.28	$14,128	40,282
2025-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	287	$140.57	$40,343	40,382
2025-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	396	$139.56	$55,265	40,669
2025-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	477	$138.57	$66,097	41,065
2025-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	240	$136.99	$32,876	41,542
2025-04-01	Marcus Gail Boxer	—	Exercise / conversion M · derivative	Stock Option (right to buy)	2,870	$0.00	$0	8,299
2025-04-01	Marcus Gail Boxer	—	Exercise / conversion M · derivative	Stock Option (right to buy)	1,130	$0.00	$0	0
2025-04-01	Marcus Gail Boxer	—	Open-market sell S	Common Stock	197	$142.82	$28,136	9,704
2025-04-01	Marcus Gail Boxer	—	Open-market sell S	Common Stock	365	$142.25	$51,923	9,901
2025-04-01	Marcus Gail Boxer	—	Open-market sell S	Common Stock	1,528	$141.13	$215,644	10,266
2025-04-01	Marcus Gail Boxer	—	Open-market sell S	Common Stock	1,512	$140.17	$211,944	11,794
2025-04-01	Marcus Gail Boxer	—	Open-market sell S	Common Stock	398	$139.33	$55,455	13,306
2025-04-01	Marcus Gail Boxer	—	Exercise / conversion M	Common Stock	2,870	$24.42	$70,085	13,704
2025-04-01	Marcus Gail Boxer	—	Exercise / conversion M	Common Stock	1,130	$7.86	$8,882	10,834
2025-03-31	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	68	$138.36	$9,408	75,557
2025-03-31	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	2,494	$138.41	$345,195	75,625
2025-03-28	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	6,250	$0.00	$0	6,250
2025-03-28	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	6,250	—	—	78,119
2025-03-17	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	6,702	$146.03	$978,678	203,354
2025-03-12	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Equity grant / award A	Common Stock	2,032	—	—	72,661
2025-03-05	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	400	$144.97	$57,988	143,768
2025-03-05	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,700	$144.12	$245,009	144,168
2025-03-05	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	2,700	$143.05	$386,239	145,868
2025-03-05	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,200	$142.08	$170,499	148,568
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	96	$162.64	$15,613	43,282
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	744	$160.85	$119,674	43,674
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	292	$158.88	$46,394	44,418
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	72	$155.66	$11,208	44,710
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	100	$162.64	$16,264	43,282
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	336	$161.58	$54,290	43,382
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	704	$160.76	$113,173	43,718
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	296	$161.64	$47,846	43,378
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	64	$155.66	$9,962	44,718
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	590	$162.06	$95,617	260,789
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	1,280	$161.04	$206,126	261,379
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	580	$159.24	$92,361	262,659
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	200	$157.80	$31,560	263,239
2025-02-26	Sheena Jonathan	—	Open-market sell S	Common Stock	50	$155.81	$7,790	263,439
2025-02-06	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,632	$177.77	$290,121	149,768
2025-02-05	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award A	Common Stock	1,522	—	—	151,400
2025-02-05	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award A	Common Stock	1,675	—	—	149,878
2025-01-31	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,886	$176.60	$333,068	101,811
2025-01-31	Chapman Steven Leonard	CEO AND PRESIDENT	Equity grant / award A	Common Stock	36,682	—	—	290,626
2025-01-29	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	2	$167.08	$334	103,697
2025-01-29	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	3,115	$165.87	$516,681	103,699
2025-01-29	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1	$167.08	$167	106,814
2025-01-29	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,217	$165.87	$201,862	106,815
2025-01-27	Sheena Jonathan	—	Equity grant / award G	Common Stock	588	$0.00	$0	261,157
2025-01-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	259	$172.44	$44,662	109,474
2025-01-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	687	$171.80	$118,027	109,733
2025-01-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	495	$171.09	$84,690	110,420
2025-01-22	Sheena Jonathan	—	Open-market sell S	Common Stock	7	$171.91	$1,203	261,745
2025-01-22	Sheena Jonathan	—	Open-market sell S	Common Stock	964	$164.95	$159,011	261,752
2025-01-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,250	$0.00	$0	3,750
2025-01-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,250	—	—	110,915
2025-01-21	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	144	$0.00	$0	0
2025-01-21	Sheena Jonathan	—	Exercise / conversion M	Common Stock	144	—	—	262,716
2025-01-20	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	191	$0.00	$0	761
2025-01-20	Sheena Jonathan	—	Exercise / conversion M	Common Stock	191	—	—	262,572
2025-01-16	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	3,043	$0.00	$0	0
2025-01-16	Sheena Jonathan	—	Equity grant / award A	Common Stock	4,966	—	—	262,381
2025-01-16	Sheena Jonathan	—	Exercise / conversion M	Common Stock	3,043	—	—	257,415
2025-01-08	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	6,223	$175.30	$1,090,901	199,804
2025-01-02	Sheena Jonathan	—	Open-market sell S	Common Stock	288	$160.70	$46,281	44,782
2025-01-02	Sheena Jonathan	—	Open-market sell S	Common Stock	732	$159.76	$116,947	45,070
2025-01-02	Sheena Jonathan	—	Open-market sell S	Common Stock	480	$158.73	$76,192	45,802
2025-01-02	Sheena Jonathan	—	Open-market sell S	Common Stock	304	$160.68	$48,848	44,782
2025-01-02	Sheena Jonathan	—	Open-market sell S	Common Stock	555	$159.69	$88,628	45,086
2025-01-02	Sheena Jonathan	—	Open-market sell S	Common Stock	641	$158.74	$101,749	45,641
2025-01-02	Sheena Jonathan	—	Open-market sell S	Common Stock	570	$160.67	$91,581	254,372
2025-01-02	Sheena Jonathan	—	Open-market sell S	Common Stock	900	$159.65	$143,688	254,942
2025-01-02	Sheena Jonathan	—	Open-market sell S	Common Stock	1,230	$158.71	$195,212	255,842
2024-12-23	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award G	Common Stock	81	$0.00	$0	114,706
2024-12-23	Fesko John	PRESIDENT, CHIEF BUS. OFFICER	Open-market sell S	Common Stock	668	$159.60	$106,616	114,142
2024-12-23	Fesko John	PRESIDENT, CHIEF BUS. OFFICER	Open-market sell S	Common Stock	1	$157.95	$158	114,810
2024-12-20	Fesko John	PRESIDENT, CHIEF BUS. OFFICER	Equity grant / award A	Common Stock	1,675	—	—	114,811
2024-12-19	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award G	Common Stock	125	$0.00	$0	114,787
2024-12-18	Sheena Jonathan	—	Open-market sell S	Common Stock	496	$168.02	$83,339	46,282
2024-12-18	Sheena Jonathan	—	Open-market sell S	Common Srock	852	$167.07	$142,347	46,778
2024-12-18	Sheena Jonathan	—	Open-market sell S	Common Stock	152	$166.01	$25,233	47,630
2024-12-18	Sheena Jonathan	—	Open-market sell S	Common Stock	303	$168.04	$50,917	46,282
2024-12-18	Sheena Jonathan	—	Open-market sell S	Common Stock	959	$167.18	$160,325	46,585
2024-12-18	Sheena Jonathan	—	Open-market sell S	Common Stock	238	$166.18	$39,550	47,544
2024-12-18	Sheena Jonathan	—	Open-market sell S	Common Stock	537	$168.15	$90,294	257,072
2024-12-18	Sheena Jonathan	—	Open-market sell S	Common Stock	1,825	$167.25	$305,231	257,609
2024-12-18	Sheena Jonathan	—	Open-market sell S	Common Stock	338	$165.97	$56,099	259,434
2024-12-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	5,300	$168.35	$892,280	2,389,180
2024-12-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	4,927	$167.39	$824,722	2,394,480
2024-12-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	45,769	$166.45	$7,618,346	2,399,407
2024-12-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	75,323	$165.45	$12,462,190	2,445,176
2024-12-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	28,681	$164.61	$4,721,211	2,520,499
2024-12-10	Chapman Rowan E	—	Open-market sell S	Common Stock	1,767	$170.24	$300,808	6,202
2024-12-09	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Exercise / conversion M · derivative	Stock Option (right to buy)	3,323	$0.00	$0	0
2024-12-09	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Exercise / conversion M · derivative	Stock Option (right to buy)	5,752	$0.00	$0	0
2024-12-09	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	4,858	$166.59	$809,312	114,912
2024-12-09	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award A	Common Stock	3,323	$12.85	$42,701	119,770
2024-12-09	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award A	Common Stock	5,752	$7.45	$42,847	116,447
2024-12-05	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	68,496	$0.00	$0	0
2024-12-05	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	68,496	$5.40	$369,556	2,549,180
2024-12-02	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	11,219	$170.54	$1,913,298	1,224,787
2024-12-02	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	40,171	$169.78	$6,820,228	1,236,006
2024-12-02	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	16,853	$168.73	$2,843,578	1,276,177
2024-12-02	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	10,447	$167.59	$1,750,792	1,293,030
2024-12-02	BOTHA ROELOF	Dir	Open-market sell S	Common Stock	8,783	$166.88	$1,465,667	1,303,477
2024-11-26	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	400	$165.55	$66,220	84,000
2024-11-26	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	940	$164.24	$154,384	84,400
2024-11-26	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	660	$163.25	$107,744	85,340
2024-11-25	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	311	$169.94	$52,851	86,000
2024-11-25	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	600	$168.91	$101,346	86,311
2024-11-25	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	1,089	$167.89	$182,831	86,911
2024-11-19	Marcus Gail Boxer	—	Open-market sell S	Common Stock	2,100	$160.52	$337,089	9,704
2024-11-19	Marcus Gail Boxer	—	Open-market sell S	Common Stock	7,582	$159.83	$1,211,842	11,804
2024-11-15	Baynes Roy D.	—	Exercise / conversion M · derivative	Stock Option (right to buy)	15,230	$0.00	$0	0
2024-11-15	Baynes Roy D.	—	Exercise / conversion M · derivative	Stock Option (right to buy)	22,000	$0.00	$0	0
2024-11-15	Baynes Roy D.	—	Open-market sell S	Common Stock	1,983	$149.98	$297,408	15,807
2024-11-15	Baynes Roy D.	—	Open-market sell S	Common Stock	2,106	$148.74	$313,250	17,790
2024-11-15	Baynes Roy D.	—	Open-market sell S	Common Stock	9,467	$147.31	$1,394,620	19,896
2024-11-15	Baynes Roy D.	—	Open-market sell S	Common Stock	1,770	$146.25	$258,871	29,363
2024-11-15	Baynes Roy D.	—	Open-market sell S	Common Stock	16,404	$145.21	$2,381,997	31,133
2024-11-15	Baynes Roy D.	—	Open-market sell S	Common Stock	5,500	$144.26	$793,419	47,537
2024-11-15	Baynes Roy D.	—	Exercise / conversion M	Common Stock	15,230	$24.42	$371,917	53,037
2024-11-15	Baynes Roy D.	—	Exercise / conversion M	Common Stock	22,000	$22.83	$502,260	37,807
2024-11-14	Marcus Gail Boxer	—	Open-market sell S	Common Stock	200	$162.04	$32,408	19,386
2024-11-14	Marcus Gail Boxer	—	Open-market sell S	Common Stock	371	$159.85	$59,306	19,586
2024-11-14	Marcus Gail Boxer	—	Open-market sell S	Common Stock	350	$159.19	$55,716	19,957
2024-11-14	Marcus Gail Boxer	—	Open-market sell S	Common Stock	791	$157.86	$124,865	20,307
2024-11-14	Marcus Gail Boxer	—	Open-market sell S	Common Stock	500	$156.75	$78,377	21,098
2024-11-13	Sheena Jonathan	—	Open-market sell S	Common Stock	458	$154.40	$70,715	51,857
2024-11-13	Sheena Jonathan	—	Open-market sell S	Common Stock	3,617	$152.93	$553,134	52,315
2024-11-13	Sheena Jonathan	—	Open-market sell S	Common Stock	4,075	$160.02	$652,065	47,782
2024-11-13	Sheena Jonathan	—	Open-market sell S	Common Stock	64	$153.51	$9,825	51,857
2024-11-13	Sheena Jonathan	—	Open-market sell S	Common Stock	4,011	$152.78	$612,806	51,921
2024-11-13	Sheena Jonathan	—	Open-market sell S	Common Stock	11,974	$154.11	$1,845,296	259,772
2024-11-13	Sheena Jonathan	—	Open-market sell S	Common Stock	8,026	$152.69	$1,225,472	271,746
2024-11-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	10,000	$0.00	$0	68,496
2024-11-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	10,000	$5.40	$53,953	2,480,684
2024-11-11	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	130,000	$0.00	$0	78,496
2024-11-11	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	130,000	$5.40	$701,389	2,470,684
2024-11-08	Sheena Jonathan	—	Open-market sell S	Common Stock	90	$131.84	$11,866	55,932
2024-11-08	Sheena Jonathan	—	Open-market sell S	Common Stock	412	$131.24	$54,070	56,022
2024-11-08	Sheena Jonathan	—	Open-market sell S	Common Stock	998	$130.47	$130,210	56,434
2024-11-08	Sheena Jonathan	—	Open-market sell S	Common Stock	764	$131.14	$100,189	55,932
2024-11-08	Sheena Jonathan	—	Open-market sell S	Common Stock	736	$130.40	$95,971	56,696
2024-11-08	Sheena Jonathan	—	Open-market sell S	Common Stock	169	$131.85	$22,283	279,772
2024-11-08	Sheena Jonathan	—	Open-market sell S	Common Stock	2,171	$130.89	$284,162	279,941
2024-11-08	Sheena Jonathan	—	Open-market sell S	Common Stock	360	$129.78	$46,720	282,112
2024-10-31	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,866	$126.45	$235,956	68,851
2024-10-28	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,057	$118.21	$124,948	206,027
2024-10-25	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	691	$118.81	$82,098	72,709
2024-10-25	ROSENMAN HERM	—	Equity grant / award A	Common Stock	178	—	—	65,765
2024-10-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	914	$119.19	$108,940	73,400
2024-10-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	496	$119.09	$59,068	74,314
2024-10-22	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	256	$120.07	$30,738	111,891
2024-10-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,250	$0.00	$0	5,000
2024-10-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,250	—	—	74,810
2024-10-21	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	143	$0.00	$0	144
2024-10-21	Sheena Jonathan	—	Exercise / conversion M	Common Stock	143	—	—	282,374
2024-10-21	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	294	$120.76	$35,503	112,147
2024-10-20	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	190	$0.00	$0	952
2024-10-20	Sheena Jonathan	—	Exercise / conversion M	Common Stock	190	—	—	282,231
2024-10-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	4,523	$130.40	$589,797	191,163
2024-10-01	Sheena Jonathan	—	Open-market sell S	Common Stock	1,025	$125.95	$129,100	57,432
2024-10-01	Sheena Jonathan	—	Open-market sell S	Common Stock	475	$124.89	$59,322	58,457
2024-10-01	Sheena Jonathan	—	Open-market sell S	Common Stock	729	$126.27	$92,051	57,432
2024-10-01	Sheena Jonathan	—	Open-market sell S	Common Stock	771	$125.23	$96,550	58,161
2024-10-01	Sheena Jonathan	—	Open-market sell S	Common Stock	427	$126.42	$53,982	282,041
2024-10-01	Sheena Jonathan	—	Open-market sell S	Common Stock	1,397	$125.83	$175,785	282,468
2024-10-01	Sheena Jonathan	—	Open-market sell S	Common Stock	876	$124.82	$109,346	283,865
2024-09-18	Sheena Jonathan	—	Open-market sell S	Common Stock	3,066	$128.07	$392,677	58,932
2024-09-18	Sheena Jonathan	—	Open-market sell S	Common Stock	6,584	$127.39	$838,704	61,998
2024-09-18	Sheena Jonathan	—	Open-market sell S	Common Stock	3,246	$128.06	$415,678	58,932
2024-09-18	Sheena Jonathan	—	Open-market sell S	Common Stock	6,404	$127.38	$815,728	62,178
2024-09-18	Sheena Jonathan	—	Open-market sell S	Common Stock	778	$128.06	$99,628	284,741
2024-09-18	Sheena Jonathan	—	Open-market sell S	Common Stock	1,922	$127.38	$244,822	285,519
2024-09-16	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	500	$130.93	$65,466	195,686
2024-09-16	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	598	$129.90	$77,678	196,186
2024-09-16	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,626	$128.87	$209,539	196,784
2024-09-16	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,258	$127.83	$160,807	198,410
2024-09-16	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,042	$126.66	$131,984	199,668
2024-09-13	Chapman Rowan E	—	Exercise / conversion M · derivative	Stock Option (right to buy)	2,614	$0.00	$0	0
2024-09-13	Chapman Rowan E	—	Open-market sell S	Common Stock	2,614	$127.68	$333,756	7,969
2024-09-13	Chapman Rowan E	—	Exercise / conversion M	Common Stock	2,614	$94.14	$246,082	10,583
2024-08-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	577	$120.00	$69,240	200,710
2024-08-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	5,006	$118.79	$594,655	201,287
2024-08-12	Sheena Jonathan	—	Open-market sell S	Common Stock	220	$115.70	$25,454	299,441
2024-08-12	Sheena Jonathan	—	Open-market sell S	Common Stock	480	$115.07	$55,234	299,661
2024-08-12	Sheena Jonathan	—	Open-market sell S	Common Stock	781	$114.11	$89,119	300,141
2024-08-12	Sheena Jonathan	—	Open-market sell S	Common Stock	1,219	$112.80	$137,507	300,922
2024-08-08	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	190,000	$0.00	$0	208,496
2024-08-08	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	190,000	$5.40	$1,025,107	1,480,648
2024-07-29	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,057	$102.77	$108,623	206,400
2024-07-26	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	751	$102.18	$76,737	75,059
2024-07-26	ROSENMAN HERM	—	Equity grant / award A	Common Stock	206	—	—	65,587
2024-07-25	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	690	$105.29	$72,650	75,810
2024-07-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	918	$105.53	$96,877	76,500
2024-07-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	499	$107.40	$53,592	77,418
2024-07-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,250	$0.00	$0	6,250
2024-07-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,059	$105.16	$111,364	77,917
2024-07-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,250	—	—	78,976
2024-07-22	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	549	$105.16	$57,733	113,637
2024-07-21	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,145	$0.00	$0	2,290
2024-07-21	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,145	—	—	77,726
2024-07-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,522	$0.00	$0	9,131
2024-07-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,522	—	—	76,581
2024-07-01	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	2,723	$108.37	$295,080	206,772
2024-07-01	Sheena Jonathan	—	Open-market sell S	Common Stock	907	$109.33	$99,163	301,808
2024-07-01	Sheena Jonathan	—	Open-market sell S	Common Stock	1,793	$108.63	$194,781	302,715
2024-06-28	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	5,000	$0.00	$0	5,000
2024-06-28	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	5,000	—	—	209,495
2024-06-18	Sheena Jonathan	—	Open-market sell S	Common Stock	2,700	$109.66	$296,080	304,508
2024-06-17	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,247	$112.55	$140,350	213,351
2024-06-17	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	3,243	$111.88	$362,811	214,598
2024-06-17	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,615	$110.35	$178,211	217,841
2024-05-30	Marcus Gail Boxer	—	Open-market sell S	Common Stock	2,000	$110.17	$220,330	18,634
2024-05-28	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	1,647	$109.96	$181,103	114,186
2024-05-23	Sheena Jonathan	—	Open-market sell S	Common Stock	236	$108.91	$25,704	68,582
2024-05-23	Sheena Jonathan	—	Open-market sell S	Common Stock	264	$107.77	$28,450	68,818
2024-05-23	Sheena Jonathan	—	Open-market sell S	Common Stock	156	$109.16	$17,029	68,582
2024-05-23	Sheena Jonathan	—	Open-market sell S	Common Stock	344	$107.90	$37,118	68,738
2024-05-16	Sheena Jonathan	—	Equity grant / award G	Common Stock	11,853	$0.00	$0	307,208
2024-05-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	3,320	$107.59	$357,201	219,456
2024-05-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	3,459	$106.59	$368,710	222,776
2024-05-10	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	30,000	$0.00	$0	12,500
2024-05-10	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	10,350	$108.09	$1,118,783	204,495
2024-05-10	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	4,255	$104.03	$442,634	214,845
2024-05-10	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	9,398	$102.91	$967,152	219,100
2024-05-10	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	5,997	$101.55	$608,998	228,498
2024-05-10	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	30,000	$19.68	$590,400	234,495
2024-05-08	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	215,000	$0.00	$0	398,496
2024-05-08	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	215,000	$5.40	$1,159,990	1,290,648
2024-05-01	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	200	$95.64	$19,128	67,542
2024-05-01	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	866	$93.88	$81,299	68,142
2024-05-01	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	400	$94.70	$37,879	67,742
2024-04-29	Fesko John	PRESIDENT, CHIEF BUS. OFFICER	Open-market sell S	Common Stock	929	$93.14	$86,526	110,748
2024-04-26	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	751	$92.00	$69,092	70,646
2024-04-26	HEALY JAMES	—	Equity grant / award A	Common Stock	210	—	—	42,710
2024-04-25	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	705	$89.55	$63,133	71,397
2024-04-25	Sheena Jonathan	—	Open-market sell S	Common Stock	500	$89.55	$44,775	69,082
2024-04-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	937	$93.00	$87,140	72,102
2024-04-23	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	531	$91.38	$48,522	117,029
2024-04-21	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	143	$0.00	$0	430
2024-04-21	Sheena Jonathan	—	Exercise / conversion M	Common Stock	143	—	—	321,364
2024-04-20	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	190	$0.00	$0	1,332
2024-04-20	Sheena Jonathan	—	Exercise / conversion M	Common Stock	190	—	—	321,221
2024-04-16	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	53,489	$91.06	$4,870,730	117,560
2024-04-16	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	26,511	$90.34	$2,394,922	171,049
2024-04-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	100	$94.44	$9,444	227,710
2024-04-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,411	$93.91	$226,417	227,810
2024-04-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	4,305	$92.67	$398,937	230,221
2024-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	7,863	$93.37	$734,140	321,031
2024-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	10,138	$92.57	$938,478	328,894
2024-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	8,699	$91.53	$796,204	339,032
2024-04-02	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,378	$92.62	$127,629	70,646
2024-03-28	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,662	$90.42	$240,687	234,526
2024-03-28	Sheena Jonathan	—	Open-market sell S	Common Stock	500	$90.13	$45,065	69,582
2024-03-28	Sheena Jonathan	—	Open-market sell S	Common Stock	313	$90.13	$28,211	347,731
2024-03-28	Sheena Jonathan	—	Open-market sell S	Common Stock	134	$90.42	$12,116	348,044
2024-03-28	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	707	$90.42	$63,924	197,560
2024-03-27	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	5,184	$0.00	$0	0
2024-03-27	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	5,184	—	—	237,188
2024-03-27	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	447	$0.00	$0	0
2024-03-27	Sheena Jonathan	—	Exercise / conversion M	Common Stock	447	—	—	348,178
2024-03-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	20,070	$89.60	$1,798,370	0
2024-03-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	20,575	$88.97	$1,830,574	20,070
2024-03-15	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	10,265	$87.98	$903,121	40,645
2024-03-07	Sheena Jonathan	—	Equity grant / award G	Common Stock	55,427	$0.00	$0	70,082
2024-03-07	Sheena Jonathan	—	Equity grant / award G	Common Stock	110,854	$0.00	$0	347,731
2024-03-06	Sheena Jonathan	—	Open-market sell S	Common Stock	1,816	$89.13	$161,857	458,585
2024-03-06	Sheena Jonathan	—	Open-market sell S	Common Stock	3,184	$88.45	$281,635	460,401
2024-03-05	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	2,227	$88.36	$196,789	198,267
2024-03-05	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	18	$87.33	$1,572	200,494
2024-03-05	Sheena Jonathan	—	Open-market sell S	Common Stock	1,028	$88.36	$90,839	463,585
2024-03-01	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Equity grant / award A	Common Stock	4,104	—	—	1,076,660
2024-02-29	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	20,526	$0.00	$0	0
2024-02-29	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	14,426	$89.72	$1,294,351	204,218
2024-02-29	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	3,400	$87.87	$298,765	218,644
2024-02-29	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	2,600	$86.67	$225,344	222,044
2024-02-29	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	100	$85.10	$8,510	224,644
2024-02-29	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	20,526	$9.29	$190,687	224,744
2024-02-29	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award A	Common Stock	3,206	—	—	200,512
2024-02-27	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	7,807	$0.00	$0	20,526
2024-02-27	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	27,500	$0.00	$0	0
2024-02-27	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	35,307	$75.09	$2,651,298	204,218
2024-02-27	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	7,807	$9.29	$72,527	239,525
2024-02-27	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	27,500	$10.41	$286,275	231,718
2024-02-23	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	380,036	$0.00	$0	0
2024-02-23	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	380,036	$2.66	$1,009,718	1,050,036
2024-02-16	ROSENMAN HERM	—	Exercise / conversion M · derivative	Stock Option (right to buy)	93,901	$0.00	$0	0
2024-02-16	ROSENMAN HERM	—	Open-market sell S	Common Stock	35,947	$69.85	$2,510,851	61,685
2024-02-16	ROSENMAN HERM	—	Open-market sell S	Common Stock	57,954	$69.08	$4,003,520	97,632
2024-02-16	ROSENMAN HERM	—	Exercise / conversion M	Common Stock	93,901	$2.66	$249,486	155,586
2024-02-06	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	23,959	$0.00	$0	0
2024-02-06	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	10,070	$0.00	$0	0
2024-02-06	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	34,029	$70.03	$2,383,129	70,646
2024-02-06	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	23,959	$19.68	$471,513	104,675
2024-02-06	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	10,070	$9.29	$93,550	80,716
2024-02-01	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	22,281	$67.73	$1,509,081	70,646
2024-01-29	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	3,235	$65.09	$210,570	92,927
2024-01-29	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Open-market sell S	Common Stock	3,426	$65.09	$223,002	194,977
2024-01-26	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Equity grant / award A	Common Stock	68,976	—	—	1,072,556
2024-01-26	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Equity grant / award A	Common Stock	31,352	—	—	96,162
2024-01-26	Moshkevich Solomon	PRESIDENT, CLINICALDIAGNOSTICS	Equity grant / award A	Common Stock	31,352	—	—	198,403
2024-01-24	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	944	$67.00	$63,248	64,810
2024-01-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,896	$65.70	$124,570	65,754
2024-01-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	306	$66.81	$20,444	67,650
2024-01-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,250	$0.00	$0	8,750
2024-01-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	771	$68.16	$52,551	67,956
2024-01-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,250	—	—	68,727
2024-01-21	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,145	$0.00	$0	4,580
2024-01-21	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,145	—	—	67,477
2024-01-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,522	$0.00	$0	12,174
2024-01-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,522	—	—	66,332
2024-01-03	Sheena Jonathan	—	Open-market sell S	Common Stock	40	$60.91	$2,437	21,155
2024-01-03	Sheena Jonathan	—	Open-market sell S	Common Stock	460	$60.42	$27,795	21,195
2024-01-03	Sheena Jonathan	—	Open-market sell S	Common Stock	500	$60.44	$30,219	21,155
2024-01-03	Sheena Jonathan	—	Open-market sell S	Common Stock	2,345	$60.67	$142,264	469,743
2024-01-03	Sheena Jonathan	—	Open-market sell S	Common Stock	2,655	$59.98	$159,235	472,088
2023-12-29	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,377	$62.29	$85,773	64,810
2023-12-28	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	915	$63.29	$57,912	66,187
2023-12-27	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	2,292	$0.00	$0	2,292
2023-12-27	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	2,292	—	—	67,102
2023-12-13	HEALY JAMES	Dir	Open-market sell S	Common Stock	644,000	$58.75	$37,835,000	0
2023-12-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Equity grant / award G · derivative	Stock Option (right to buy)	380,036	$0.00	$0	380,036
2023-12-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Equity grant / award G	Common Stock	250,000	$0.00	$0	1,003,580
2023-12-08	Marcus Gail Boxer	—	Open-market sell S	Common Stock	500	$57.52	$28,760	20,146
2023-12-06	Sheena Jonathan	—	Open-market sell S	Common Stock	400	$58.88	$23,552	474,743
2023-12-06	Sheena Jonathan	—	Open-market sell S	Common Stock	4,600	$58.16	$267,526	475,143
2023-11-29	Chapman Rowan E	—	Open-market sell S	Common Stock	1,998	$55.97	$111,831	9,373
2023-11-21	Marcus Gail Boxer	—	Open-market sell S	Common Stock	1,000	$54.31	$54,314	20,646
2023-11-20	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,566	$55.00	$141,130	217,554
2023-11-02	Sheena Jonathan	—	Open-market sell S	Common Stock	500	$40.23	$20,115	22,155
2023-11-02	Sheena Jonathan	—	Open-market sell S	Common Stock	5,000	$40.23	$201,150	479,743
2023-10-27	Williams Brinkley Ruth	—	Equity grant / award A · derivative	Stock Option (right to buy)	515	$25.03	$12,890	515
2023-10-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	203	$40.90	$8,302	64,810
2023-10-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	2,172	$40.37	$87,682	65,013
2023-10-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,565	$40.39	$63,211	67,185
2023-10-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,250	$0.00	$0	10,000
2023-10-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,250	—	—	68,750
2023-10-21	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,145	$0.00	$0	5,725
2023-10-21	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,145	—	—	67,500
2023-10-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,522	$0.00	$0	13,696
2023-10-20	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,522	—	—	66,355
2023-09-29	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,372	$45.98	$63,080	64,833
2023-09-28	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	919	$45.82	$42,105	66,205
2023-09-27	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	2,291	$0.00	$0	4,584
2023-09-27	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	2,291	—	—	67,124
2023-09-06	Sheena Jonathan	—	Open-market sell S	Common Stock	500	$59.22	$29,610	23,155
2023-09-06	Sheena Jonathan	—	Open-market sell S	Common Stock	498	$59.59	$29,675	489,746
2023-09-06	Sheena Jonathan	—	Open-market sell S	Common Stock	4,502	$59.02	$265,690	490,244
2023-09-01	Sheena Jonathan	—	Open-market sell S	Common Stock	10,000	$60.01	$600,062	494,746
2023-08-11	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,578	$55.00	$141,790	214,988
2023-08-02	Sheena Jonathan	—	Open-market sell S	Common Stock	5,000	$44.22	$221,116	504,746
2023-08-02	Sheena Jonathan	—	Open-market sell S	Common Stock	500	$44.15	$22,075	23,655
2023-07-28	Williams Brinkley Ruth	—	Equity grant / award A · derivative	Stock Option (right to buy)	428	$29.68	$12,703	428
2023-07-25	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	2,347	$46.58	$109,323	64,833
2023-07-24	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	800	$47.83	$38,261	178,478
2023-07-21	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	644	$0.00	$0	3,864
2023-07-21	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	644	—	—	179,278
2023-07-20	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	856	$0.00	$0	8,560
2023-07-20	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	856	—	—	178,634
2023-06-30	ROSENMAN HERM	—	Equity grant / award A · derivative	Stock Option (right to buy)	4,255	$0.00	$0	4,255
2023-06-30	ROSENMAN HERM	—	Equity grant / award A	Common Stock	2,750	—	—	60,548
2023-06-29	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,377	$51.11	$70,378	64,833
2023-06-28	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	915	$50.88	$46,556	66,210
2023-06-28	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,605	$50.88	$132,545	214,983
2023-06-27	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	2,292	$0.00	$0	6,875
2023-06-27	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	2,292	—	—	67,125
2023-06-27	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	5,183	$0.00	$0	15,550
2023-06-27	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	5,183	—	—	217,588
2023-06-13	Chapman Rowan E	—	Open-market sell S	Common Stock	1,767	$50.58	$89,366	8,621
2023-06-07	Sheena Jonathan	—	Open-market sell S	Common Stock	348	$49.39	$17,189	24,655
2023-06-07	Sheena Jonathan	—	Open-market sell S	Common Stock	152	$48.41	$7,359	25,003
2023-06-07	Sheena Jonathan	—	Open-market sell S	Common Stock	3,283	$49.43	$162,281	514,746
2023-06-07	Sheena Jonathan	—	Open-market sell S	Common Stock	1,717	$48.54	$83,346	518,029
2023-05-25	HEALY JAMES	—	Exercise / conversion M · derivative	Restricted Stock Unit	3,534	$0.00	$0	0
2023-05-25	HEALY JAMES	—	Exercise / conversion M	Common Stock	3,534	—	—	38,762
2023-05-10	Sheena Jonathan	—	Open-market sell S	Common Stock	2,175	$54.50	$118,548	519,746
2023-05-10	Sheena Jonathan	—	Open-market sell S	Common Stock	2,825	$53.72	$151,771	521,921
2023-04-25	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	2,364	$50.99	$120,550	64,833
2023-04-24	Sheena Jonathan	—	Open-market sell S	Common Stock	43	$54.98	$2,364	524,746
2023-04-21	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	143	$0.00	$0	1,002
2023-04-21	Sheena Jonathan	—	Exercise / conversion M	Common Stock	143	—	—	524,789
2023-04-21	Sheena Jonathan	—	Open-market sell S	Common Stock	233	$54.22	$12,634	524,646
2023-04-21	Sheena Jonathan	—	Open-market sell S	Common Stock	57	$54.27	$3,093	524,879
2023-04-20	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	190	$0.00	$0	2,093
2023-04-20	Sheena Jonathan	—	Exercise / conversion M	Common Stock	190	—	—	524,936
2023-04-14	Williams Brinkley Ruth	—	Equity grant / award A · derivative	Stock Option (right to buy)	120	$32.88	$3,946	120
2023-04-03	Sheena Jonathan	—	Open-market sell S	Common Stock	5,000	$54.02	$270,081	524,746
2023-03-29	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,571	$55.00	$141,405	209,819
2023-03-29	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Equity grant / award G	Common Stock	613,496	$0.00	$0	0
2023-03-28	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,612	$55.13	$144,002	212,390
2023-03-27	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	5,183	$0.00	$0	20,733
2023-03-27	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	5,183	—	—	215,002
2023-03-24	Williams Brinkley Ruth	—	Equity grant / award A · derivative	Stock Option (right to buy)	10,767	$0.00	$0	10,767
2023-03-23	Sheena Jonathan	—	Open-market sell S	Common Stock	135	$56.08	$7,571	529,433
2023-03-22	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	455	$0.00	$0	0
2023-03-22	Sheena Jonathan	—	Exercise / conversion M	Common Stock	455	—	—	529,568
2023-03-22	Sheena Jonathan	—	Open-market sell S	Common Stock	1,259	$56.32	$70,909	529,113
2023-03-17	Sheena Jonathan	—	Equity grant / award A	Common Stock	1,259	—	—	530,372
2023-03-02	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,377	$56.54	$77,859	175,387
2023-03-02	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	6,435	$56.08	$360,863	176,764
2023-03-02	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	1,400	$55.02	$77,031	183,199
2023-03-02	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	100	$53.05	$5,305	184,599
2023-02-27	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	2,289	$0.00	$0	0
2023-02-27	Sheena Jonathan	—	Exercise / conversion M	Common Stock	2,289	—	—	529,113
2023-02-01	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	4,152	$44.35	$184,152	49,664
2023-02-01	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	10,413	$43.81	$456,204	53,816
2023-02-01	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	4,761	$42.81	$203,796	64,229
2023-01-31	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	35,000	$42.33	$1,481,560	68,990
2023-01-30	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,509	$43.14	$65,098	103,990
2023-01-30	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	47,188	$42.05	$1,984,227	105,499
2023-01-27	Chapman Steven Leonard	CEO AND PRESIDENT	Equity grant / award A	Common Stock	127,265	—	—	231,044
2023-01-23	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Open-market sell S	Common Stock	2,387	$41.56	$99,203	148,853
2023-01-21	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	644	$0.00	$0	5,152
2023-01-21	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	644	—	—	151,240
2023-01-20	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	3,424	$0.00	$0	10,272
2023-01-20	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	3,424	—	—	150,596
2023-01-13	HEALY JAMES	—	Equity grant / award A	Common Stock	390	$40.01	$15,604	34,943
2023-01-10	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	3,938	$0.00	$0	38,134
2023-01-10	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	3,938	$13.01	$51,233	11,824
2023-01-09	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	2,244	$37.62	$84,419	7,886
2023-01-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	3,985	$0.00	$0	0
2023-01-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	3,985	—	—	10,130
2023-01-03	Sheena Jonathan	—	Open-market sell S	Common Stock	1,236	$39.55	$48,888	570,074
2022-12-31	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	4,141	$0.00	$0	0
2022-12-31	Sheena Jonathan	—	Exercise / conversion M	Common Stock	4,141	—	—	571,310
2022-12-28	Sheena Jonathan	—	Open-market sell S	Common Stock	134	$39.84	$5,339	567,169
2022-12-27	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	447	$0.00	$0	2,235
2022-12-27	Sheena Jonathan	—	Exercise / conversion M	Common Stock	447	—	—	567,303
2022-12-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	429	$42.30	$18,147	89,974
2022-12-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,077	$0.00	$0	1,078
2022-12-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,077	—	—	90,403
2022-12-07	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	1,146	$0.00	$0	23,949
2022-12-07	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	9,158	$0.00	$0	0
2022-12-07	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,645	$38.31	$101,330	80,985
2022-12-07	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	1,146	$13.01	$14,909	83,630
2022-12-07	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	9,158	$9.29	$85,078	82,484
2022-11-16	HEALY JAMES	Dir	Open-market sell S	Common Stock	2,400	$37.71	$90,498	0
2022-10-24	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	3,135	$42.41	$132,957	4,932
2022-10-22	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	5,000	$0.00	$0	15,000
2022-10-22	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	5,000	—	—	8,067
2022-10-21	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,145	$0.00	$0	10,306
2022-10-21	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	1,145	—	—	3,067
2022-10-18	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	1,922	$0.00	$0	42,072
2022-10-18	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	1,922	$13.01	$25,005	1,922
2022-10-14	ROSENMAN HERM	—	Equity grant / award A	Common Stock	399	$45.42	$18,123	53,480
2022-10-10	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	2,008	$42.12	$84,571	3,915
2022-10-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	3,984	$0.00	$0	3,985
2022-10-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	3,984	—	—	5,923
2022-10-03	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,559	$44.43	$69,266	72,457
2022-10-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	3,125	$0.00	$0	3,125
2022-10-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,125	—	—	74,016
2022-09-27	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	447	$0.00	$0	2,682
2022-09-27	Sheena Jonathan	—	Exercise / conversion M	Common Stock	447	—	—	566,438
2022-09-23	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,674	$45.30	$75,828	68,313
2022-09-23	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,674	$45.30	$75,828	71,438
2022-09-22	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	3,125	$0.00	$0	6,250
2022-09-22	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	182	$0.00	$0	366
2022-09-22	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,125	—	—	73,112
2022-09-22	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	182	—	—	69,987
2022-07-21	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	143	$0.00	$0	1,431
2022-07-21	Sheena Jonathan	—	Exercise / conversion M	Common Stock	143	—	—	565,536
2022-07-20	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	1,281	$0.00	$0	43,994
2022-07-20	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	1,281	$13.01	$16,666	4,607
2022-07-08	Bertagnolli Monica	—	Equity grant / award A	Common Stock	344	$0.00	$0	998
2022-07-08	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	2,019	$39.51	$79,778	3,326
2022-07-08	ROSENMAN HERM	—	Equity grant / award A · derivative	Restricted Stock Unit	499	$36.31	$18,119	499
2022-07-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	3,985	$0.00	$0	7,969
2022-07-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	3,985	—	—	5,345
2022-07-05	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,550	$36.93	$57,242	68,916
2022-07-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	3,125	$0.00	$0	6,250
2022-07-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,125	—	—	70,466
2022-06-27	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	447	$0.00	$0	3,129
2022-06-27	Sheena Jonathan	—	Exercise / conversion M	Common Stock	447	—	—	565,393
2022-06-22	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	455	$0.00	$0	1,365
2022-06-22	Sheena Jonathan	—	Exercise / conversion M	Common Stock	455	—	—	564,946
2022-05-27	ROSENMAN HERM	—	Equity grant / award A · derivative	Stock Option (right to buy)	7,068	$0.00	$0	7,068
2022-05-27	ROSENMAN HERM	—	Equity grant / award A · derivative	Restricted Stock Unit	3,534	$0.00	$0	3,534
2022-05-25	Marcus Gail Boxer	—	Exercise / conversion M · derivative	Restricted Stock Unit	2,614	$0.00	$0	0
2022-05-25	Marcus Gail Boxer	—	Exercise / conversion M	Common Stock	2,614	—	—	8,326
2022-05-18	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	3,202	$0.00	$0	45,275
2022-05-18	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	3,202	$13.01	$41,658	3,202
2022-05-13	Sheena Jonathan	—	Equity grant / award A · derivative	Restricted Stock Unit	4,141	$0.00	$0	4,141
2022-05-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market buy P	Common Stock	19,011	$29.56	$562,055	420,000
2022-05-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market buy P	Common Stock	159,783	$28.81	$4,603,348	400,989
2022-05-12	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market buy P	Common Stock	41,026	$28.09	$1,152,359	241,026
2022-04-21	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	143	$0.00	$0	1,574
2022-04-21	Sheena Jonathan	—	Exercise / conversion M	Common Stock	143	—	—	564,491
2022-04-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Restricted Stock Unit	307	$0.00	$0	0
2022-04-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	307	—	—	634,546
2022-04-08	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	1,999	$41.91	$83,779	3,352
2022-04-08	BOTHA ROELOF	—	Equity grant / award A · derivative	Stock Option (right to buy)	735	$28.91	$21,249	735
2022-04-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	3,984	$0.00	$0	12,056
2022-04-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	3,984	—	—	5,351
2022-04-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,559	$43.09	$67,177	62,242
2022-04-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	3,125	$0.00	$0	9,375
2022-04-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,125	—	—	63,801
2022-03-28	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	1,382	$39.63	$54,767	1,367
2022-03-27	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	2,749	$0.00	$0	21,996
2022-03-27	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	2,749	—	—	2,749
2022-03-23	Sheena Jonathan	—	Open-market sell S	Common Stock	138	$40.60	$5,603	564,035
2022-03-22	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	455	$0.00	$0	1,820
2022-03-22	Sheena Jonathan	—	Exercise / conversion M	Common Stock	455	—	—	564,173
2022-03-16	BOTHA ROELOF	Dir	Open-market buy P	Common Stock	40,695	$33.49	$1,362,798	1,291,584
2022-03-16	BOTHA ROELOF	Dir	Open-market buy P	Common Stock	85,903	$32.59	$2,799,983	1,250,889
2022-03-16	BOTHA ROELOF	Dir	Open-market buy P	Common Stock	26,402	$31.92	$842,630	1,164,986
2022-03-14	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Stock Option (right to buy)	160,000	$0.00	$0	380,036
2022-03-14	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	160,000	$2.66	$425,104	678,838
2022-03-10	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,197	$42.16	$50,466	78,231
2022-03-09	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	3,021	$0.00	$0	0
2022-03-09	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	3,021	—	—	79,428
2022-03-04	Sheena Jonathan	—	Other disposed transaction F	Common Stock	1,088	$58.39	$63,528	540,170
2022-03-02	Sheena Jonathan	—	Equity grant / award A	Common Stock	3,225	$0.00	$0	541,258
2022-02-07	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	20,000	$0.00	$0	21,950
2022-02-07	Sheena Jonathan	—	Exercise / conversion M	Common Stock	20,000	$1.14	$22,820	544,483
2022-01-28	Sheena Jonathan	—	Equity grant / award A · derivative	Restricted Stock Unit	3,043	$0.00	$0	3,043
2022-01-24	Sheena Jonathan	—	Open-market sell S	Common Stock	208	$59.95	$12,469	524,483
2022-01-21	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	572	$0.00	$0	1,717
2022-01-21	Sheena Jonathan	—	Exercise / conversion M	Common Stock	572	—	—	524,691
2022-01-19	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	25,000	$0.00	$0	41,950
2022-01-19	Sheena Jonathan	—	Exercise / conversion M	Common Stock	25,000	$1.14	$28,525	524,119
2022-01-14	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	40,000	$0.00	$0	21,353
2022-01-14	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	40,385	$0.00	$0	0
2022-01-14	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	40,000	$10.41	$416,400	136,809
2022-01-14	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Exercise / conversion M	Common Stock	40,385	$9.59	$387,292	96,809
2022-01-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Restricted Stock Unit	307	$0.00	$0	307
2022-01-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	307	—	—	426,019
2022-01-07	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	20,000	$0.00	$0	66,950
2022-01-07	Sheena Jonathan	—	Exercise / conversion M	Common Stock	20,000	$1.14	$22,820	499,119
2022-01-05	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	4,995	$82.61	$412,637	51,911
2022-01-04	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	9,375	$0.00	$0	0
2022-01-04	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	9,375	—	—	56,906
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	18,750	$0.00	$0	0
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	2,084	$0.00	$0	31,250
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	4,072	$0.00	$0	25,095
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	3,052	$0.00	$0	9,158
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,209	$91.52	$110,648	47,531
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,310	$90.83	$118,985	48,740
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,493	$89.29	$133,305	50,050
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	10,005	$88.44	$884,803	51,543
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	12,890	$87.82	$1,131,977	61,548
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,260	$86.22	$194,847	74,438
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	18,750	$25.46	$477,375	76,698
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	2,084	$20.27	$42,243	57,948
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	4,072	$13.01	$52,977	55,864
2022-01-03	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,052	$9.29	$28,353	51,792
2022-01-03	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	20,000	$0.00	$0	86,950
2022-01-03	Sheena Jonathan	—	Exercise / conversion M	Common Stock	20,000	$1.14	$22,820	479,119
2022-01-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	3,125	$0.00	$0	12,500
2022-01-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,125	—	—	48,740
2021-12-28	Sheena Jonathan	—	Open-market sell S	Common Stock	202	$91.34	$18,451	459,119
2021-12-27	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	447	$0.00	$0	4,023
2021-12-27	Sheena Jonathan	—	Exercise / conversion M	Common Stock	447	—	—	459,321
2021-12-23	Sheena Jonathan	—	Open-market sell S	Common Stock	204	$92.99	$18,970	458,874
2021-12-22	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	455	$0.00	$0	2,275
2021-12-22	Sheena Jonathan	—	Exercise / conversion M	Common Stock	455	—	—	459,078
2021-12-21	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	5,000	$0.00	$0	48,477
2021-12-21	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	3,329	$93.43	$311,012	62,283
2021-12-21	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	3,671	$92.58	$339,848	65,612
2021-12-21	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	2,293	$93.43	$214,237	21,517
2021-12-21	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	2,707	$92.59	$250,635	23,810
2021-12-21	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	5,000	$13.01	$65,050	26,517
2021-12-10	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	1,196	$91.33	$109,231	65,662
2021-12-09	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	3,021	$0.00	$0	3,021
2021-12-09	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	3,021	—	—	66,858
2021-12-08	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	1,281	$0.00	$0	53,477
2021-12-08	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	1,281	$13.01	$16,666	21,517
2021-12-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	4,411	$91.99	$405,777	20,236
2021-12-04	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	8,750	$0.00	$0	0
2021-12-04	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	8,750	—	—	24,647
2021-12-01	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	2,083	$0.00	$0	33,334
2021-12-01	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	3,053	$0.00	$0	12,210
2021-12-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	3,904	$91.09	$355,629	35,586
2021-12-01	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	3,315	$90.45	$299,826	39,490
2021-12-01	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	2,083	$20.27	$42,222	42,805
2021-12-01	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,053	$9.29	$28,362	38,639
2021-11-17	Bertagnolli Monica	—	Exercise / conversion M · derivative	Restricted Stock Unit	654	$0.00	$0	1,306
2021-11-17	Bertagnolli Monica	—	Exercise / conversion M	Common Stock	654	—	—	654
2021-11-10	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stook	895	$112.62	$100,797	58,588
2021-11-10	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stoock	2,422	$112.03	$271,330	59,483
2021-11-10	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	22,178	$110.98	$2,461,294	61,905
2021-11-08	ROSENMAN HERM	—	Exercise / conversion M · derivative	Stock Option (right to buy)	44,503	$0.00	$0	93,901
2021-11-08	ROSENMAN HERM	—	Open-market sell S	Common Stock	400	$120.24	$48,096	51,275
2021-11-08	ROSENMAN HERM	—	Open-market sell S	Common Stock	2,832	$119.62	$338,758	51,675
2021-11-08	ROSENMAN HERM	—	Open-market sell S	Common Stock	2,100	$118.79	$249,455	54,507
2021-11-08	ROSENMAN HERM	—	Open-market sell S	Common Stock	39,171	$17.13	$670,893	56,607
2021-11-08	ROSENMAN HERM	—	Exercise / conversion M	Common Stock	44,503	$2.66	$118,240	95,778
2021-11-08	ROSENMAN HERM	—	Exercise / conversion M · derivative	Stock Option (right to buy)	44,503	$0.00	$0	93,901
2021-11-08	ROSENMAN HERM	—	Open-market sell S	Common Stock	400	$120.24	$48,096	51,275
2021-11-08	ROSENMAN HERM	—	Open-market sell S	Common Stock	2,832	$119.62	$338,758	51,675
2021-11-08	ROSENMAN HERM	—	Open-market sell S	Common Stock	2,100	$118.79	$249,455	54,507
2021-11-08	ROSENMAN HERM	—	Open-market sell S	Common Stock	39,171	$117.13	$4,587,993	56,607
2021-11-08	ROSENMAN HERM	—	Exercise / conversion M	Common Stock	44,503	$2.66	$118,240	95,778
2021-11-01	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	6,000	$0.00	$0	54,758
2021-11-01	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	6,000	$120.00	$720,010	15,897
2021-11-01	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	6,000	$13.01	$78,060	27,897
2021-10-22	RABINOWITZ DANIEL	SEC. AND CHIEF LEGAL OFFICER	Equity grant / award A · derivative	Restricted Stock Unit	10,000	$0.00	$0	10,000
2021-10-14	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	122	$112.19	$13,687	582,494
2021-10-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Restricted Stock Unit	307	$0.00	$0	614
2021-10-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	307	—	—	582,616
2021-10-12	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	1,281	$0.00	$0	60,758
2021-10-12	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	1,281	$13.01	$16,666	23,178
2021-10-08	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	1,986	$117.08	$232,521	25,213
2021-10-08	BOTHA ROELOF	—	Equity grant / award A · derivative	Stock Option (right to buy)	252	$74.31	$18,726	252
2021-10-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	3,984	$0.00	$0	19,923
2021-10-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	3,984	—	—	27,199
2021-10-05	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,608	$110.91	$178,343	37,103
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	2,084	$0.00	$0	37,500
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	37	$111.54	$4,127	0
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	431	$110.23	$47,510	37
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,239	$108.81	$134,811	468
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	4,966	$108.07	$536,658	1,707
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	5,139	$106.97	$549,698	6,673
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,084	$105.88	$114,769	11,812
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	258	$111.54	$28,777	38,711
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	256	$110.24	$28,222	38,969
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,870	$108.81	$203,465	39,225
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,784	$107.89	$192,470	41,095
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	2,084	$20.27	$42,243	42,879
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	154	$111.54	$17,177	38,711
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	500	$109.26	$54,630	38,865
2021-10-04	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,831	$108.20	$198,122	39,365
2021-10-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	3,125	$0.00	$0	15,625
2021-10-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,125	—	—	41,196
2021-09-28	Sheena Jonathan	—	Open-market sell S	Common Stock	201	$109.76	$22,061	457,381
2021-09-28	Sheena Jonathan	—	Open-market sell S	Common Stock	8	$108.59	$869	457,582
2021-09-27	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	447	$0.00	$0	4,470
2021-09-27	Sheena Jonathan	—	Exercise / conversion M	Common Stock	447	—	—	457,590
2021-09-27	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	2,749	—	—	30,646
2021-09-24	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,454	$121.52	$298,206	35,586
2021-09-24	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	5,802	$120.52	$699,256	38,040
2021-09-24	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	10,125	$118.91	$1,204,007	43,842
2021-09-24	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	5,292	$117.97	$624,311	53,967
2021-09-24	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	3,241	$116.69	$378,178	59,259
2021-09-23	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,649	$125.67	$207,230	62,500
2021-09-22	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	3,125	$0.00	$0	18,750
2021-09-22	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	182	$0.00	$0	1,094
2021-09-22	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,125	—	—	64,149
2021-09-22	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	182	—	—	61,024
2021-09-17	Chapman Rowan E	—	Exercise / conversion M · derivative	Stock Option (right to buy)	5,500	$0.00	$0	11,000
2021-09-17	Chapman Rowan E	—	Open-market sell S	Common Stock	4,500	$120.93	$544,167	4,856
2021-09-17	Chapman Rowan E	—	Open-market sell S	Common Stock	1,000	$120.08	$120,083	9,356
2021-09-17	Chapman Rowan E	—	Exercise / conversion M	Common Stock	5,500	$32.15	$176,825	10,356
2021-09-10	Sheena Jonathan	—	Open-market sell S	Common Stock	1,030	$119.53	$123,114	456,892
2021-09-09	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	2,292	$0.00	$0	4,584
2021-09-09	Sheena Jonathan	—	Exercise / conversion M	Common Stock	2,292	—	—	457,922
2021-09-02	Cozzens Todd C	—	Exercise / conversion M · derivative	Stock Option (right to buy)	10,578	$0.00	$0	591
2021-09-02	Cozzens Todd C	—	Exercise / conversion M · derivative	Stock Option (right to buy)	11,169	$0.00	$0	0
2021-09-02	Cozzens Todd C	—	Exercise / conversion M · derivative	Stock Option (right to buy)	2,733	$0.00	$0	0
2021-09-02	Cozzens Todd C	—	Open-market sell S	Common Stock	4,764	$122.71	$584,570	23,865
2021-09-02	Cozzens Todd C	—	Open-market sell S	Common Stock	10,666	$121.96	$1,300,862	17,963
2021-09-02	Cozzens Todd C	—	Open-market sell S	Common Stock	8,841	$120.96	$1,069,428	28,629
2021-09-02	Cozzens Todd C	—	Exercise / conversion M	Common Stock	10,578	$10.41	$110,117	37,470
2021-09-02	Cozzens Todd C	—	Exercise / conversion M	Common Stock	11,169	$11.80	$131,794	26,892
2021-09-02	Cozzens Todd C	—	Exercise / conversion M	Common Stock	2,733	$1.39	$3,787	15,723
2021-09-01	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	5,424	$0.00	$0	9,980
2021-09-01	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	6,545	$0.00	$0	26,835
2021-09-01	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	552	$0.00	$0	39,615
2021-09-01	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	1,018	$0.00	$0	0
2021-09-01	Sheena Jonathan	—	Open-market sell S	Common Stock	13,539	$121.12	$1,639,873	455,630
2021-09-01	Sheena Jonathan	—	Exercise / conversion M	Common Stock	5,424	$9.29	$50,389	469,169
2021-09-01	Sheena Jonathan	—	Exercise / conversion M	Commom Stock	6,545	$10.41	$68,133	463,745
2021-09-01	Sheena Jonathan	—	Exercise / conversion M	Common Stock	552	$9.59	$5,294	457,200
2021-09-01	Sheena Jonathan	—	Exercise / conversion M	Common Stock	1,018	$5.40	$5,492	456,648
2021-08-30	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	1,942	$0.00	$0	15,404
2021-08-30	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	1,900	$0.00	$0	33,380
2021-08-30	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	168	$0.00	$0	40,167
2021-08-30	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	310	$0.00	$0	1,018
2021-08-30	Sheena Jonathan	—	Open-market sell S	Common Stock	4,320	$121.36	$524,284	455,630
2021-08-30	Sheena Jonathan	—	Exercise / conversion M	Common Stock	1,942	$9.29	$18,041	459,950
2021-08-30	Sheena Jonathan	—	Exercise / conversion M	Common Stock	1,900	$10.41	$19,779	458,008
2021-08-30	Sheena Jonathan	—	Exercise / conversion M	Common Stock	168	$9.59	$1,611	456,108
2021-08-30	Sheena Jonathan	—	Exercise / conversion M	Common Stock	310	$5.40	$1,673	455,940
2021-08-17	Chapman Rowan E	—	Exercise / conversion M · derivative	Stock Option (right to buy)	5,500	$0.00	$0	16,500
2021-08-17	Chapman Rowan E	—	Open-market sell S	Common Stock	5,500	$100.09	$550,477	4,856
2021-08-17	Chapman Rowan E	—	Exercise / conversion M	Common Stock	5,500	$32.15	$176,825	10,356
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	9,375	$0.00	$0	28,125
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	4,570	$0.00	$0	23,320
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	7,617	$0.00	$0	38,867
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	3,242	$0.00	$0	44,909
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	5,285	$0.00	$0	26,652
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	25	$0.00	$0	25
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	24,062	$101.82	$2,450,089	74,961
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	9,294	$101.24	$940,952	99,023
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	9,375	$25.46	$238,688	108,317
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	4,570	$25.46	$116,352	98,942
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	7,617	$13.01	$99,097	91,130
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,242	$20.27	$65,715	94,372
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	5,285	$9.29	$49,098	80,271
2021-08-12	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	25	$10.73	$268	74,986
2021-08-11	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Stock Option (right to buy)	1,281	$0.00	$0	62,039
2021-08-11	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	1,281	$13.01	$16,666	26,498
2021-07-23	BOTHA ROELOF	—	Equity grant / award A · derivative	Stock Option (right to buy)	252	$74.17	$18,691	252
2021-07-22	HEALY JAMES	Dir	Open-market buy P	Common Stock	2,400	$113.00	$271,200	2,400
2021-07-19	Chapman Rowan E	—	Exercise / conversion M · derivative	Stock Option (right to buy)	3,000	$0.00	$0	2,712
2021-07-19	Chapman Rowan E	—	Open-market sell S	Common Stock	232	$111.83	$25,945	4,856
2021-07-19	Chapman Rowan E	—	Open-market sell S	Common Stock	1,468	$108.47	$159,231	5,088
2021-07-19	Chapman Rowan E	—	Open-market sell S	Common Stock	1,300	$107.53	$139,792	6,556
2021-07-19	Chapman Rowan E	—	Exercise / conversion M	Common Stock	3,000	$40.93	$122,790	7,856
2021-07-14	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Open-market sell S	Common Stock	76	$116.20	$8,831	580,126
2021-07-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M · derivative	Restricted Stock Unit	307	$0.00	$0	921
2021-07-13	Rabinowitz Matthew	EXECUTIVE CHAIRMAN	Exercise / conversion M	Common Stock	307	—	—	580,202
2021-07-12	Sheena Jonathan	—	Open-market sell S	Common Stock	168	$122.68	$20,611	455,630
2021-07-12	Sheena Jonathan	—	Open-market sell S	Common Stock	1,201	$121.30	$145,677	455,798
2021-07-12	Sheena Jonathan	—	Exercise / conversion M · derivative	Common Stock	784	$0.00	$0	18,046
2021-07-12	Sheena Jonathan	—	Exercise / conversion M · derivative	Common Stock	488	$0.00	$0	35,680
2021-07-12	Sheena Jonathan	—	Exercise / conversion M · derivative	Common Stock	32	$0.00	$0	40,400
2021-07-12	Sheena Jonathan	—	Exercise / conversion M · derivative	Common Stock	65	$0.00	$0	1,515
2021-07-09	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	2,623	$0.00	$0	18,830
2021-07-09	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	2,200	$0.00	$0	36,168
2021-07-09	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	346	$0.00	$0	40,432
2021-07-09	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	378	$0.00	$0	1,580
2021-07-09	Sheena Jonathan	—	Open-market sell S	Common Stock	5,547	$121.00	$671,187	455,630
2021-07-09	Sheena Jonathan	—	Exercise / conversion M	Common Stock	2,623	$9.29	$24,368	461,177
2021-07-09	Sheena Jonathan	—	Exercise / conversion M	Common Stock	2,200	$10.41	$22,902	458,554
2021-07-09	Sheena Jonathan	—	Exercise / conversion M	Common Stock	346	$9.59	$3,318	456,354
2021-07-09	Sheena Jonathan	—	Exercise / conversion M	Common Stock	378	$5.40	$2,039	456,008
2021-07-08	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	2,032	$113.34	$230,302	25,217
2021-07-07	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	4,633	$117.98	$546,601	74,961
2021-07-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	3,984	$0.00	$0	23,907
2021-07-07	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	3,984	—	—	27,249
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	27	$0.00	$0	50
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	4,922	$0.00	$0	27,890
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	8,203	$0.00	$0	46,484
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	2,370	$0.00	$0	48,151
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Stock Option (right to buy)	2,404	$0.00	$0	31,937
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	17	$118.59	$2,016	79,594
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	3,126	$117.24	$366,481	79,611
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	2,835	$116.59	$330,533	82,737
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	708	$118.37	$83,808	85,572
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	13,543	$117.13	$1,586,264	86,280
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	6,045	$116.43	$703,834	99,823
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	27	$10.73	$290	105,868
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	4,922	$25.46	$125,314	105,841
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	8,203	$13.01	$106,721	98,549
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	2,370	$20.27	$48,040	100,919
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	2,404	$9.29	$22,333	87,976
2021-07-06	Chapman Steven Leonard	CEO AND PRESIDENT	Open-market sell S	Common Stock	1,558	$118.59	$184,763	85,572
2021-07-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	9,375	$0.00	$0	9,375
2021-07-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M · derivative	Restricted Stock Unit	3,125	$0.00	$0	18,750
2021-07-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	9,375	—	—	87,130
2021-07-02	Chapman Steven Leonard	CEO AND PRESIDENT	Exercise / conversion M	Common Stock	3,125	—	—	77,755
2021-07-01	Schueren Robert Alan	CHIEF OPERATING OFFICER	Equity grant / award G	Common Stock	600	$0.00	$0	53,863
2021-06-28	Schueren Robert Alan	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	1,381	$117.57	$162,366	23,265
2021-06-28	Sheena Jonathan	—	Open-market sell S	Common Stock	201	$117.57	$23,632	455,630
2021-06-27	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	2,749	$0.00	$0	30,244
2021-06-27	Schueren Robert Alan	CHIEF OPERATING OFFICER	Exercise / conversion M	Common Stock	2,749	—	—	24,646
2021-06-27	Sheena Jonathan	—	Exercise / conversion M · derivative	Restricted Stock Unit	446	$0.00	$0	4,917
2021-06-27	Sheena Jonathan	—	Exercise / conversion M	Common Stock	446	—	—	455,831
2021-06-25	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	700	$0.00	$0	21,453
2021-06-25	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	52	$0.00	$0	40,778
2021-06-25	Sheena Jonathan	—	Exercise / conversion M · derivative	Stock Option (right to buy)	87	$0.00	$0	1,958
2021-06-25	Sheena Jonathan	—	Open-market sell S	Common Stock	700	$121.59	$85,111	455,385
2021-06-25	Sheena Jonathan	—	Exercise / conversion M	Common Stock	700	$9.29	$6,503	456,085
2021-06-25	Sheena Jonathan	—	Open-market sell S	Common Stock	52	$121.63	$6,325	455,385
2021-06-25	Sheena Jonathan	—	Exercise / conversion M	Common Stock	52	$9.59	$499	455,437
2021-06-25	Sheena Jonathan	—	Open-market sell S	Common Stock	87	$121.63	$10,582	455,385
2021-06-25	Sheena Jonathan	—	Exercise / conversion M	Common Stock	87	$5.40	$469	455,472
2021-06-23	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	430	$115.18	$49,526	96,378
2021-06-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M · derivative	Restricted Stock Unit	1,077	$0.00	$0	7,541
2021-06-22	Brophy Michael Burkes	CHIEF FINANCIAL OFFICER	Exercise / conversion M	Common Stock	1,077	—	—	96,808

Regulatory Activity

Last 12 months to 2025-04-29

Insider Filings (Forms 3/4/5) — 12 months

Material Event Filings (8-K) — 12 months

8-K Material Event Filing Activity

Monthly count

Insider Trading Activity (Forms 3/4/5)

Monthly count