Financial Metrics

PTCT PTC THERAPEUTICS, INC.

Range: 2016-01-01 to 2026-04-29

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Financial Statements

Grouped by statement

Income Statement

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2021-03-31	-1.83	—	USD/shares	10-Q	2022-05-03
Quarterly	2021-06-30	-1.68	+8.2%	USD/shares	10-Q	2022-08-04
Quarterly	2021-09-30	-1.89	-12.5%	USD/shares	10-Q	2022-10-27
Quarterly	2022-03-31	-1.78	+5.8%	USD/shares	10-Q	2023-04-27
Quarterly	2022-06-30	-2.13	-19.7%	USD/shares	10-Q	2023-08-03
Quarterly	2022-09-30	-1.53	+28.2%	USD/shares	10-Q	2023-10-26
Quarterly	2023-03-31	-1.88	-22.9%	USD/shares	10-Q	2024-04-25
Quarterly	2023-06-30	-2.66	-41.5%	USD/shares	10-Q	2024-08-08
Quarterly	2023-09-30	-1.76	+33.8%	USD/shares	10-Q	2024-11-07
Quarterly	2024-03-31	-1.2	+31.8%	USD/shares	10-Q	2025-05-06
Quarterly	2024-06-30	-1.29	-7.5%	USD/shares	10-Q	2025-08-07
Quarterly	2024-09-30	-1.39	-7.8%	USD/shares	10-Q	2025-11-04
Quarterly	2025-03-31	10.04	+822.3%	USD/shares	10-Q	2025-05-06
Quarterly	2025-06-30	-0.83	-108.3%	USD/shares	10-Q	2025-08-07
Quarterly	2025-09-30	0.2	+124.1%	USD/shares	10-Q	2025-11-04
Annual	2019-12-31	-4.27	—	USD/shares	10-K	2022-02-22
Annual	2020-12-31	-6.64	-55.5%	USD/shares	10-K	2023-02-21
Annual	2021-12-31	-7.43	-11.9%	USD/shares	10-K	2024-02-29
Annual	2022-12-31	-7.79	-4.8%	USD/shares	10-K	2025-02-27
Annual	2023-12-31	-8.37	-7.4%	USD/shares	10-K	2026-02-19
Annual	2024-12-31	-4.73	+43.5%	USD/shares	10-K	2026-02-19
Annual	2025-12-31	7.78	+264.5%	USD/shares	10-K	2026-02-19

Balance Sheet

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-03-31	93366000.0	—	USD	10-Q	2016-05-05
Quarterly	2016-06-30	94936000.0	+1.7%	USD	10-Q	2016-08-04
Quarterly	2016-09-30	96559000.0	+1.7%	USD	10-Q	2016-11-03
Quarterly	2016-12-31	98216000.0	+1.7%	USD	10-Q	2017-11-02
Quarterly	2017-03-31	99895000.0	+1.7%	USD	10-Q	2017-05-08
Quarterly	2017-06-30	141242000.0	+41.4%	USD	10-Q	2017-08-09
Quarterly	2017-09-30	143091000.0	+1.3%	USD	10-Q	2017-11-02
Quarterly	2017-12-31	144971000.0	+1.3%	USD	10-Q	2018-11-05
Quarterly	2018-03-31	146878000.0	+1.3%	USD	10-Q	2018-05-09
Quarterly	2018-06-30	147204000.0	+0.2%	USD	10-Q	2018-08-07
Quarterly	2018-09-30	144258000.0	-2.0%	USD	10-Q	2018-11-05
Quarterly	2018-12-31	141347000.0	-2.0%	USD	10-Q	2019-10-30
Quarterly	2019-03-31	138468000.0	-2.0%	USD	10-Q	2019-05-02
Quarterly	2019-06-30	135683000.0	-2.0%	USD	10-Q	2019-08-06
Quarterly	2019-09-30	293149000.0	+116.1%	USD	10-Q	2019-10-30
Quarterly	2019-12-31	293859000.0	+0.2%	USD	10-Q	2020-10-29
Quarterly	2020-03-31	294574000.0	+0.2%	USD	10-Q	2020-04-30
Quarterly	2020-06-30	297029000.0	+0.8%	USD	10-Q	2020-08-05
Quarterly	2020-09-30	302971000.0	+2.0%	USD	10-Q	2020-10-29
Quarterly	2020-12-31	309145000.0	+2.0%	USD	10-Q	2021-10-28
Quarterly	2021-03-31	430038000.0	+39.1%	USD	10-Q	2021-05-04
Quarterly	2021-06-30	430496000.0	+0.1%	USD	10-Q	2021-07-29
Quarterly	2021-09-30	281604000.0	-34.6%	USD	10-Q	2021-10-28
Quarterly	2021-12-31	281894000.0	+0.1%	USD	10-Q	2022-10-27
Quarterly	2022-03-31	282176000.0	+0.1%	USD	10-Q	2022-05-03
Quarterly	2022-06-30	282460000.0	+0.1%	USD	10-Q	2022-08-04
Quarterly	2022-09-30	282749000.0	+0.1%	USD	10-Q	2022-10-27
Quarterly	2022-12-31	571722000.0	+102.2%	USD	10-Q	2023-10-26
Quarterly	2023-03-31	572091000.0	+0.1%	USD	10-Q	2023-04-27
Quarterly	2023-06-30	572643000.0	+0.1%	USD	10-Q	2023-08-03
Quarterly	2023-09-30	573174000.0	+0.1%	USD	10-Q	2023-10-26
Quarterly	2023-12-31	284213000.0	-50.4%	USD	10-Q	2024-11-07
Quarterly	2024-03-31	284512000.0	+0.1%	USD	10-Q	2024-04-25
Quarterly	2024-06-30	284806000.0	+0.1%	USD	10-Q	2024-08-08
Quarterly	2024-09-30	285106000.0	+0.1%	USD	10-Q	2024-11-07
Quarterly	2024-12-31	285412000.0	+0.1%	USD	10-Q	2025-11-04
Quarterly	2025-03-31	285712000.0	+0.1%	USD	10-Q	2025-05-06
Quarterly	2025-06-30	286013000.0	+0.1%	USD	10-Q	2025-08-07
Annual	2016-12-31	98216000.0	—	USD	10-K	2018-03-06
Annual	2017-12-31	144971000.0	+47.6%	USD	10-K	2019-03-01
Annual	2018-12-31	141347000.0	-2.5%	USD	10-K	2020-03-02
Annual	2019-12-31	293859000.0	+107.9%	USD	10-K	2021-02-25
Annual	2020-12-31	309145000.0	+5.2%	USD	10-K	2022-02-22
Annual	2021-12-31	281894000.0	-8.8%	USD	10-K	2023-02-21
Annual	2022-12-31	571722000.0	+102.8%	USD	10-K	2024-02-29
Annual	2023-12-31	284213000.0	-50.3%	USD	10-K	2025-02-27
Annual	2024-12-31	285412000.0	+0.4%	USD	10-K	2026-02-19

Cash Flow

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-03-31	265000.0	—	USD	10-Q	2017-05-08
Quarterly	2016-06-30	275000.0	+3.8%	USD	10-Q	2017-08-09
Quarterly	2016-09-30	540000.0	+96.4%	USD	10-Q	2017-11-02
Quarterly	2017-03-31	225000.0	-58.3%	USD	10-Q	2018-05-09
Quarterly	2017-06-30	579000.0	+157.3%	USD	10-Q	2018-08-07
Quarterly	2017-09-30	1058000.0	+82.7%	USD	10-Q	2018-11-05
Quarterly	2018-03-31	479000.0	-54.7%	USD	10-Q	2019-05-02
Quarterly	2018-06-30	1187000.0	+147.8%	USD	10-Q	2019-08-06
Quarterly	2018-09-30	2489000.0	+109.7%	USD	10-Q	2019-10-30
Quarterly	2019-03-31	2865000.0	+15.1%	USD	10-Q	2020-04-30
Quarterly	2019-06-30	4851000.0	+69.3%	USD	10-Q	2020-08-05
Quarterly	2019-09-30	9104000.0	+87.7%	USD	10-Q	2020-10-29
Quarterly	2020-03-31	6023000.0	-33.8%	USD	10-Q	2021-05-04
Quarterly	2020-06-30	8183000.0	+35.9%	USD	10-Q	2021-07-29
Quarterly	2020-09-30	11491000.0	+40.4%	USD	10-Q	2021-10-28
Quarterly	2021-03-31	5669000.0	-50.7%	USD	10-Q	2022-05-03
Quarterly	2021-06-30	13643000.0	+140.7%	USD	10-Q	2022-08-04
Quarterly	2021-09-30	19487000.0	+42.8%	USD	10-Q	2022-10-27
Quarterly	2022-03-31	9312000.0	-52.2%	USD	10-Q	2023-04-27
Quarterly	2022-06-30	18012000.0	+93.4%	USD	10-Q	2023-08-03
Quarterly	2022-09-30	23394000.0	+29.9%	USD	10-Q	2023-10-26
Quarterly	2023-03-31	10270000.0	-56.1%	USD	10-Q	2024-04-25
Quarterly	2023-06-30	16515000.0	+60.8%	USD	10-Q	2024-08-08
Quarterly	2023-09-30	22872000.0	+38.5%	USD	10-Q	2024-11-07
Quarterly	2024-03-31	9588000.0	-58.1%	USD	10-Q	2025-05-06
Quarterly	2024-06-30	2213000.0	-76.9%	USD	10-Q	2025-08-07
Quarterly	2024-09-30	2735000.0	+23.6%	USD	10-Q	2025-11-04
Quarterly	2025-03-31	1724000.0	-37.0%	USD	10-Q	2025-05-06
Quarterly	2025-06-30	3041000.0	+76.4%	USD	10-Q	2025-08-07
Quarterly	2025-09-30	6486000.0	+113.3%	USD	10-Q	2025-11-04
Annual	2016-12-31	1776000.0	—	USD	10-K	2019-03-01
Annual	2017-12-31	3101000.0	+74.6%	USD	10-K	2020-03-02
Annual	2018-12-31	7097000.0	+128.9%	USD	10-K	2021-02-25
Annual	2019-12-31	13757000.0	+93.8%	USD	10-K	2022-02-22
Annual	2020-12-31	17843000.0	+29.7%	USD	10-K	2023-02-21
Annual	2021-12-31	28213000.0	+58.1%	USD	10-K	2024-02-29
Annual	2022-12-31	32016000.0	+13.5%	USD	10-K	2025-02-27
Annual	2023-12-31	28438000.0	-11.2%	USD	10-K	2026-02-19
Annual	2024-12-31	6502000.0	-77.1%	USD	10-K	2026-02-19
Annual	2025-12-31	8860000.0	+36.3%	USD	10-K	2026-02-19

Share Data

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-03-31	33919169.0	—	shares	10-Q	2017-05-08
Quarterly	2016-06-30	34000333.0	+0.2%	shares	10-Q	2017-08-09
Quarterly	2016-09-30	34088741.0	+0.3%	shares	10-Q	2017-11-02
Quarterly	2017-03-31	34305948.0	+0.6%	shares	10-Q	2018-05-09
Quarterly	2017-06-30	39621738.0	+15.5%	shares	10-Q	2018-08-07
Quarterly	2017-09-30	41296740.0	+4.2%	shares	10-Q	2018-11-05
Quarterly	2018-03-31	41626617.0	+0.8%	shares	10-Q	2019-05-02
Quarterly	2018-06-30	46137833.0	+10.8%	shares	10-Q	2019-08-06
Quarterly	2018-09-30	48096521.0	+4.2%	shares	10-Q	2019-10-30
Quarterly	2019-03-31	55855111.0	+16.1%	shares	10-Q	2020-04-30
Quarterly	2019-06-30	55912748.0	+0.1%	shares	10-Q	2020-08-05
Quarterly	2019-09-30	56463528.0	+1.0%	shares	10-Q	2020-10-29
Quarterly	2020-03-31	62389158.0	+10.5%	shares	10-Q	2021-05-04
Quarterly	2020-06-30	65150780.0	+4.4%	shares	10-Q	2021-07-29
Quarterly	2020-09-30	67641171.0	+3.8%	shares	10-Q	2021-10-28
Quarterly	2021-03-31	70188602.0	+3.8%	shares	10-Q	2022-05-03
Quarterly	2021-06-30	70414632.0	+0.3%	shares	10-Q	2022-08-04
Quarterly	2021-09-30	70585938.0	+0.2%	shares	10-Q	2022-10-27
Quarterly	2022-03-31	71215105.0	+0.9%	shares	10-Q	2023-04-27
Quarterly	2022-06-30	71372940.0	+0.2%	shares	10-Q	2023-08-03
Quarterly	2022-09-30	71654671.0	+0.4%	shares	10-Q	2023-10-26
Quarterly	2023-03-31	73729284.0	+2.9%	shares	10-Q	2024-04-25
Quarterly	2023-06-30	74730433.0	+1.4%	shares	10-Q	2024-08-08
Quarterly	2023-09-30	75377997.0	+0.9%	shares	10-Q	2024-11-07
Quarterly	2024-03-31	76496127.0	+1.5%	shares	10-Q	2025-05-06
Quarterly	2024-06-30	76725070.0	+0.3%	shares	10-Q	2025-08-07
Quarterly	2024-09-30	76925523.0	+0.3%	shares	10-Q	2025-11-04
Quarterly	2025-03-31	86385922.0	+12.3%	shares	10-Q	2025-05-06
Quarterly	2025-06-30	78151240.0	-9.5%	shares	10-Q	2025-08-07
Quarterly	2025-09-30	87115369.0	+11.5%	shares	10-Q	2025-11-04
Annual	2016-12-31	34044584.0	—	shares	10-K	2019-03-01
Annual	2017-12-31	39183073.0	+15.1%	shares	10-K	2020-03-02
Annual	2018-12-31	46576313.0	+18.9%	shares	10-K	2021-02-25
Annual	2019-12-31	58863185.0	+26.4%	shares	10-K	2022-02-22
Annual	2020-12-31	66027908.0	+12.2%	shares	10-K	2023-02-21
Annual	2021-12-31	70466393.0	+6.7%	shares	10-K	2024-02-29
Annual	2022-12-31	71728634.0	+1.8%	shares	10-K	2025-02-27
Annual	2023-12-31	74838292.0	+4.3%	shares	10-K	2026-02-19
Annual	2024-12-31	76845055.0	+2.7%	shares	10-K	2026-02-19
Annual	2025-12-31	88311494.0	+14.9%	shares	10-K	2026-02-19

Credit and Bond Coverage

Company-level

Long-Term Debt (latest annual)

285,412,000

Total Liabilities (latest annual)

3,104,080,000

Current Liabilities (latest annual)

968,427,000

Metrics

Frequency	Period End	Value	% Chg	Unit	Form	Filed
Quarterly	2016-03-31	-0.2104	—	ratio	10-Q	2017-05-08
Quarterly	2016-06-30	-43.9706	-20801.4%	ratio	10-Q	2017-08-09
Quarterly	2016-09-30	-46.5172	-5.8%	ratio	10-Q	2017-11-02
Quarterly	2017-03-31	33.1701	+171.3%	ratio	10-Q	2018-05-09
Quarterly	2017-06-30	-8.7419	-126.4%	ratio	10-Q	2018-08-07
Quarterly	2017-09-30	-11.1975	-28.1%	ratio	10-Q	2018-11-05
Quarterly	2018-03-31	-0.1282	+98.9%	ratio	10-Q	2019-05-02
Quarterly	2018-06-30	-0.0356	+72.2%	ratio	10-Q	2019-08-06
Quarterly	2018-09-30	-0.1320	-270.8%	ratio	10-Q	2019-10-30
Quarterly	2019-03-31	-0.1406	-6.5%	ratio	10-Q	2020-04-30
Quarterly	2019-06-30	-0.0855	+39.2%	ratio	10-Q	2020-08-05
Quarterly	2019-09-30	-0.0904	-5.7%	ratio	10-Q	2020-10-29
Quarterly	2020-03-31	-0.2131	-135.7%	ratio	10-Q	2021-05-04
Quarterly	2020-06-30	-0.3169	-48.7%	ratio	10-Q	2021-07-29
Quarterly	2020-09-30	-0.1364	+57.0%	ratio	10-Q	2021-10-28
Quarterly	2021-03-31	-0.4397	-222.4%	ratio	10-Q	2022-05-03
Quarterly	2021-06-30	-0.6022	-37.0%	ratio	10-Q	2022-08-04
Quarterly	2021-09-30	-1.2735	-111.5%	ratio	10-Q	2022-10-27
Quarterly	2022-03-31	1.3990	+209.9%	ratio	10-Q	2023-04-27
Quarterly	2022-06-30	0.8346	-40.3%	ratio	10-Q	2023-08-03
Quarterly	2022-09-30	0.4818	-42.3%	ratio	10-Q	2023-10-26
Quarterly	2023-03-31	0.3037	-37.0%	ratio	10-Q	2024-04-25
Quarterly	2023-06-30	0.3433	+13.1%	ratio	10-Q	2024-08-08
Quarterly	2023-09-30	0.1982	-42.3%	ratio	10-Q	2024-11-07
Quarterly	2024-03-31	0.1024	-48.3%	ratio	10-Q	2025-05-06
Quarterly	2024-06-30	0.1012	-1.2%	ratio	10-Q	2025-08-07
Quarterly	2024-09-30	0.1012	-0.0%	ratio	10-Q	2025-11-04
Quarterly	2025-03-31	-4.6650	-4711.6%	ratio	10-Q	2025-05-06
Quarterly	2025-06-30	0.3140	+106.7%	ratio	10-Q	2025-08-07
Quarterly	2025-09-30	-0.1021	-132.5%	ratio	10-Q	2025-11-04
Annual	2016-12-31	-1.1884	—	ratio	10-K	2019-03-01
Annual	2017-12-31	-0.5050	+57.5%	ratio	10-K	2020-03-02
Annual	2018-12-31	-0.3652	+27.7%	ratio	10-K	2021-02-25
Annual	2019-12-31	-0.4233	-15.9%	ratio	10-K	2022-02-22
Annual	2020-12-31	-0.9091	-114.8%	ratio	10-K	2023-02-21
Annual	2021-12-31	-364.3261	-39976.4%	ratio	10-K	2024-02-29
Annual	2022-12-31	1.6106	+100.4%	ratio	10-K	2025-02-27
Annual	2023-12-31	0.7655	-52.5%	ratio	10-K	2026-02-19
Annual	2024-12-31	0.3308	-56.8%	ratio	10-K	2026-02-19
Annual	2025-12-31	-3.3249	-1105.0%	ratio	10-K	2026-02-19

8-K Material Event Details

69 filings · 184 item records

This 8-K section tracks corporate event disclosures, not insider buy/sell sentiment. Insider trading direction is shown in the insider section below.

Event Type Distribution

Count per 8-K item

Insider Transaction History

807 transaction records

Net Insider Flow

Monthly open-market buy value minus open-market sell value

Monthly Insider Activity Mix

Share volume split between open-market trades, grants, and exercises

Transaction Value Timeline

Each circle = one priced transaction; size ∝ value X-axis date:

All Transactions

Date	Insider	Title	Type	Security	Shares	Price	Total Value	Post-Tx Shares
2026-04-06	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,265	$0.00	$0	6,798
2026-04-06	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	1,443	$69.75	$100,649	105,212
2026-04-06	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	822	$68.91	$56,644	106,655
2026-04-06	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	2,265	$39.42	$89,286	107,477
2026-04-02	Golden Lee Scott	EVP & CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	829	$67.99	$56,364	79,115
2026-04-01	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	80	$70.30	$5,624	60,137
2026-04-01	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	12,530	$69.50	$870,835	60,217
2026-04-01	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	39,393	$68.89	$2,713,784	72,747
2026-03-24	Chutter Jessica Caroline	—	Equity grant / award A · derivative	Stock Option (Right to Buy)	2,896	$0.00	$0	2,896
2026-03-24	Chutter Jessica Caroline	—	Equity grant / award A · derivative	Stock Option (Right to Buy)	3,475	$0.00	$0	3,475
2026-03-24	Chutter Jessica Caroline	—	Equity grant / award A	Common Stock	3,333	$0.00	$0	7,333
2026-03-24	Chutter Jessica Caroline	—	Equity grant / award A	Common Stock	4,000	$0.00	$0	4,000
2026-03-12	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	2,662	$64.08	$170,581	396,920
2026-03-11	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Equity grant / award A	Common Stock	12,500	$0.00	$0	399,582
2026-03-10	Okey Stephanie	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	14,000	$0.00	$0	0
2026-03-10	Okey Stephanie	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,167	$0.00	$0	0
2026-03-10	Okey Stephanie	—	Open-market sell S	Common Stock	14,000	$70.00	$980,000	8,000
2026-03-10	Okey Stephanie	—	Exercise / conversion M	Common Stock	14,000	$33.63	$470,820	22,000
2026-03-10	Okey Stephanie	—	Open-market sell S	Common Stock	1,167	$70.00	$81,690	8,000
2026-03-10	Okey Stephanie	—	Exercise / conversion M	Common Stock	1,167	$33.63	$39,246	9,167
2026-03-05	Okey Stephanie	—	Open-market sell S	Common Stock	6,333	$63.38	$401,386	8,000
2026-02-19	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	590	$69.82	$41,194	105,212
2026-02-19	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	212	$68.54	$14,530	105,802
2026-02-19	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	1,629	$69.82	$113,737	106,014
2026-02-19	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	588	$68.54	$40,302	107,643
2026-02-18	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	3,081	$69.36	$213,698	108,231
2026-02-18	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Open-market sell S	Common Stock	2,494	$69.36	$172,984	70,199
2026-02-17	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,813	$0.00	$0	22,501
2026-02-17	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	2	$70.13	$140	111,312
2026-02-17	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	2,811	$69.29	$194,774	111,314
2026-02-17	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	2,813	$25.69	$72,266	114,125
2026-01-08	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Open-market sell S	Common Stock	1,034	$76.45	$79,049	72,693
2026-01-07	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Open-market sell S	Common Stock	1,235	$77.45	$95,651	73,727
2026-01-06	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Open-market sell S	Common Stock	1,381	$76.95	$106,268	74,962
2026-01-02	Smith Mary L.	—	Equity grant / award A · derivative	Stock Option (Right to Buy)	3,475	$0.00	$0	3,475
2026-01-02	Smith Mary L.	—	Equity grant / award A	Common Stock	4,000	$0.00	$0	21,813
2025-12-30	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	8,089	$76.64	$619,941	341,875
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	19,805	$0.00	$0	0
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	565	$0.00	$0	17,566
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	138	$0.00	$0	19,805
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	3,220	$78.33	$252,223	70,373
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	10,548	$77.55	$817,997	73,593
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	4,537	$76.33	$346,309	84,141
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	1,500	$75.77	$113,655	88,678
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	19,805	$66.49	$1,316,834	90,178
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	313	$77.73	$24,329	70,432
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	193	$75.45	$14,562	70,745
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	565	$18.01	$10,176	70,938
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	59	$78.43	$4,627	70,373
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	42	$77.26	$3,245	70,432
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	37	$75.66	$2,799	70,474
2025-12-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	138	$66.49	$9,176	70,511
2025-12-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	251	$0.00	$0	18,131
2025-12-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,951	$0.00	$0	19,943
2025-12-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	2,831	$75.07	$212,523	70,373
2025-12-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	2,831	$66.49	$188,233	73,204
2025-12-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	251	$75.00	$18,825	70,373
2025-12-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	251	$18.01	$4,521	70,624
2025-12-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	120	$75.02	$9,002	70,373
2025-12-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	120	$66.49	$7,979	70,493
2025-12-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,684	$0.00	$0	18,382
2025-12-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	36,606	$0.00	$0	22,894
2025-12-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	35,261	$75.44	$2,660,090	70,473
2025-12-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	35,361	$66.49	$2,351,153	105,734
2025-12-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	100	$76.00	$7,600	70,373
2025-12-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	3,584	$75.31	$269,911	70,473
2025-12-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	3,684	$18.01	$66,349	74,157
2025-12-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	1,245	$75.28	$93,724	72,912
2025-12-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	1,245	$66.49	$82,780	74,157
2025-12-16	SCHMERTZLER MICHAEL	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	24,000	$0.00	$0	0
2025-12-16	SCHMERTZLER MICHAEL	—	Exercise / conversion M	Common Stock	24,000	$30.86	$740,640	155,266
2025-12-03	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	733	$0.00	$0	734
2025-12-03	Reeve Emma	—	Open-market sell S	Common Stock	733	$78.62	$57,628	6,666
2025-12-03	Reeve Emma	—	Exercise / conversion M	Common Stock	733	$46.54	$34,114	7,399
2025-12-02	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	3,428	$79.07	$271,052	349,964
2025-12-01	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Equity grant / award A	Common Stock	15,625	$0.00	$0	353,392
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	11,399	$0.00	$0	0
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	47,624	$0.00	$0	0
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	8,410	$0.00	$0	0
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,020	$0.00	$0	47,624
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,475	$0.00	$0	8,410
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	2,621	$84.54	$221,579	100,825
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	4,834	$83.39	$403,107	103,446
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	3,744	$82.61	$309,292	108,280
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	11,399	$33.02	$376,395	112,024
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	3,095	$85.15	$263,539	100,625
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	9,171	$84.42	$774,216	103,720
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	21,844	$83.33	$1,820,261	112,891
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	13,514	$82.55	$1,115,581	134,735
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	47,624	$33.02	$1,572,544	148,249
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	200	$85.34	$17,068	100,625
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	1,757	$84.56	$148,572	100,825
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	3,663	$83.41	$305,531	102,582
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	2,790	$82.82	$231,068	106,245
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	8,410	$18.01	$151,464	109,035
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	180	$85.17	$15,331	100,625
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	289	$84.61	$24,452	100,805
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	862	$83.35	$71,848	101,094
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	689	$82.63	$56,932	101,956
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	2,020	$33.02	$66,700	102,645
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	574	$84.67	$48,601	100,625
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	990	$83.44	$82,606	101,199
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	911	$82.63	$75,276	102,189
2025-11-25	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	2,475	$18.01	$44,575	103,100
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,101	$0.00	$0	11,399
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	21,206	$0.00	$0	49,644
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,715	$0.00	$0	10,885
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,650	$0.00	$0	70,850
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,900	$0.00	$0	15,600
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	6,101	$80.17	$489,117	100,625
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	6,101	$33.02	$201,455	106,726
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	21,206	$80.19	$1,700,509	100,625
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	21,206	$33.02	$700,222	121,831
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	4,715	$80.15	$377,907	100,625
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	4,715	$18.01	$84,917	105,340
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	1,650	$80.14	$132,231	100,625
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	1,650	$33.02	$54,483	102,275
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	1,900	$80.14	$152,266	100,625
2025-11-24	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	1,900	$18.01	$34,219	102,525
2025-11-21	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	0
2025-11-21	Reeve Emma	—	Open-market sell S	Common Stock	10,000	$79.50	$795,000	6,666
2025-11-21	Reeve Emma	—	Exercise / conversion M	Common Stock	10,000	$51.16	$511,600	16,666
2025-11-20	Okey Stephanie	—	Equity grant / award G	Common Stock	867	$0.00	$0	8,000
2025-11-17	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,812	$0.00	$0	25,314
2025-11-17	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	192	$77.18	$14,819	103,901
2025-11-17	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	777	$76.53	$59,464	104,093
2025-11-17	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	1,843	$75.64	$139,405	104,870
2025-11-17	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	2,812	$25.69	$72,240	106,713
2025-11-12	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,333	$0.00	$0	1,467
2025-11-12	Reeve Emma	—	Open-market sell S	Common Stock	7,333	$74.50	$546,308	6,666
2025-11-12	Reeve Emma	—	Exercise / conversion M	Common Stock	7,333	$46.54	$341,278	13,999
2025-10-30	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	12,000	$0.00	$0	0
2025-10-30	Reeve Emma	—	Open-market sell S	Common Stock	12,000	$69.50	$834,000	6,666
2025-10-30	Reeve Emma	—	Exercise / conversion M	Common Stock	12,000	$38.10	$457,200	18,666
2025-10-30	Reeve Emma	—	Open-market sell S	Common Stock	3,666	$69.50	$254,787	6,666
2025-10-07	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,375	$0.00	$0	3,376
2025-10-07	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	312	$64.97	$20,271	103,901
2025-10-07	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	1,306	$63.80	$83,323	104,213
2025-10-07	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	1,757	$62.89	$110,498	105,519
2025-10-07	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	3,375	$38.10	$128,588	107,276
2025-10-03	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	8,650	$0.00	$0	0
2025-10-03	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,912	$0.00	$0	0
2025-10-03	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	0
2025-10-03	Reeve Emma	—	Open-market sell S	Common Stock	1,884	$66.89	$126,021	10,332
2025-10-03	Reeve Emma	—	Open-market sell S	Common Stock	4,037	$66.10	$266,846	12,216
2025-10-03	Reeve Emma	—	Open-market sell S	Common Stock	2,729	$65.05	$177,521	16,253
2025-10-03	Reeve Emma	—	Exercise / conversion M	Common Stock	8,650	$33.63	$290,900	18,982
2025-10-03	Reeve Emma	—	Open-market sell S	Common Stock	1,600	$66.93	$107,088	10,332
2025-10-03	Reeve Emma	—	Open-market sell S	Common Stock	3,149	$66.11	$208,180	11,932
2025-10-03	Reeve Emma	—	Open-market sell S	Common Stock	2,163	$65.02	$140,638	15,081
2025-10-03	Reeve Emma	—	Exercise / conversion M	Common Stock	6,912	$33.02	$228,234	17,244
2025-10-03	Reeve Emma	—	Open-market sell S	Common Stock	2,381	$66.87	$159,217	10,332
2025-10-03	Reeve Emma	—	Open-market sell S	Common Stock	4,591	$66.09	$303,419	12,713
2025-10-03	Reeve Emma	—	Open-market sell S	Common Stock	3,028	$65.09	$197,093	17,304
2025-10-03	Reeve Emma	—	Exercise / conversion M	Common Stock	10,000	$39.42	$394,200	20,332
2025-09-11	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	837	$0.00	$0	0
2025-09-11	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	0
2025-09-11	Reeve Emma	—	Open-market sell S	Common Stock	837	$59.50	$49,802	10,332
2025-09-11	Reeve Emma	—	Exercise / conversion M	Common Stock	837	$33.63	$28,148	11,169
2025-09-11	Reeve Emma	—	Open-market sell S	Common Stock	10,000	$59.50	$595,000	10,332
2025-09-11	Reeve Emma	—	Exercise / conversion M	Common Stock	10,000	$25.69	$256,900	20,332
2025-09-11	Reeve Emma	—	Open-market sell S	Common Stock	1,334	$59.50	$79,373	10,332
2025-09-11	Reeve Emma	—	Open-market sell S	Common Stock	3,534	$59.50	$210,273	11,666
2025-09-09	SOUTHWELL DAVID P	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	12,000	$0.00	$0	0
2025-09-09	SOUTHWELL DAVID P	—	Open-market sell S	Common Stock	12,000	$58.34	$700,080	16,850
2025-09-09	SOUTHWELL DAVID P	—	Exercise / conversion M	Common Stock	12,000	$30.86	$370,320	28,850
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,250	$0.00	$0	0
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,238	$0.00	$0	1,250
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,406	$0.00	$0	0
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,713	$0.00	$0	0
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	8,528	$0.00	$0	0
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,017	$0.00	$0	2,406
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	16,698	$0.00	$0	3,713
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	1,250	$56.86	$71,075	72,912
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	1,250	$11.32	$14,150	74,162
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	1,238	$56.85	$70,380	72,912
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	1,238	$11.32	$14,014	74,150
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	2,406	$56.92	$136,950	72,912
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	2,406	$11.23	$27,019	75,318
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	3,713	$56.92	$211,344	72,912
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	3,713	$30.86	$114,583	76,625
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	8,528	$56.92	$485,414	72,912
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	8,528	$18.01	$153,589	81,440
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	6,017	$56.91	$342,427	72,912
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	6,017	$11.23	$67,571	78,929
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	16,698	$56.94	$950,784	72,912
2025-09-08	Pauwels Eric	CHIEF BUSINESS OFFICER	Exercise / conversion M	Common Stock	16,698	$30.86	$515,300	89,610
2025-08-28	Jacobson Allan Steven	—	Open-market sell S	Common Stock	1,667	$50.15	$83,600	17,451
2025-08-15	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,813	$0.00	$0	24,899
2025-08-15	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	2,813	$48.58	$136,656	103,901
2025-08-15	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	2,813	$25.69	$72,266	106,714
2025-08-05	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	10,739	$51.74	$555,636	337,767
2025-08-01	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Equity grant / award A	Common Stock	75,000	$0.00	$0	348,506
2025-07-15	Gravier Pierre	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	2,516	$49.46	$124,441	71,920
2025-05-16	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	883	$0.00	$0	27,712
2025-05-16	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	883	$46.02	$40,636	103,901
2025-05-16	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	883	$25.69	$22,684	104,784
2025-05-15	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,929	$0.00	$0	28,595
2025-05-15	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	1,929	$46.18	$89,081	103,901
2025-05-15	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	1,929	$25.69	$49,556	105,830
2025-04-22	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	2,804	$48.74	$136,656	273,234
2025-04-02	Golden Lee Scott	EVP & CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	897	$46.95	$42,114	75,997
2025-03-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	300	$58.31	$17,493	72,640
2025-03-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	3,340	$57.67	$192,618	72,940
2025-03-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	1,085	$56.62	$61,433	76,280
2025-03-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	2,037	$55.24	$112,524	77,365
2025-03-14	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	4,458	$55.19	$246,037	79,402
2025-03-13	Okey Stephanie	—	Open-market sell S	Common Stock	5,000	$54.00	$270,000	8,867
2025-03-12	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,395	$0.00	$0	0
2025-03-12	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	13,126	$0.00	$0	0
2025-03-12	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	2,395	$53.23	$127,486	103,901
2025-03-12	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	2,395	$33.02	$79,083	106,296
2025-03-12	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	13,126	$53.31	$699,747	103,901
2025-03-12	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	13,126	$33.02	$433,421	117,027
2025-03-11	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,719	$0.00	$0	2,395
2025-03-11	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,662	$0.00	$0	13,126
2025-03-11	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	1,719	$53.01	$91,124	103,901
2025-03-11	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	1,719	$33.02	$56,761	105,620
2025-03-11	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	5,662	$53.02	$300,199	103,901
2025-03-11	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	5,662	$33.02	$186,959	109,563
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	11,249	$0.00	$0	33,751
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	11,398	$0.00	$0	4,114
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	45,392	$0.00	$0	18,788
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	7,762	$53.05	$411,774	103,901
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	3,487	$52.24	$182,161	111,663
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	11,249	$25.69	$288,987	115,150
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	11,398	$53.12	$605,462	103,901
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	11,398	$33.02	$376,362	115,299
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	45,392	$53.15	$2,412,585	103,901
2025-03-10	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	45,392	$33.02	$1,498,844	149,293
2025-03-04	Jacobson Allan Steven	—	Open-market sell S	Common Stock	1,230	$51.52	$63,370	19,118
2025-02-20	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Open-market sell S	Common Stock	878	$50.12	$44,009	62,564
2025-02-19	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Open-market sell S	Common Stock	879	$50.10	$44,034	63,442
2025-01-08	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Open-market sell S	Common Stock	1,662	$44.50	$73,959	64,321
2025-01-07	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Open-market sell S	Common Stock	1,291	$45.34	$58,534	65,983
2025-01-03	Young Alethia	—	Equity grant / award A · derivative	Stock Option (Right to Buy)	8,800	$0.00	$0	8,800
2025-01-03	Young Alethia	—	Equity grant / award A	Common Stock	4,000	$0.00	$0	17,067
2024-12-31	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	8,279	$45.16	$373,880	217,528
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,060	$0.00	$0	0
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	66,956	$0.00	$0	0
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,594	$0.00	$0	66,956
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	277	$52.76	$14,615	4,576
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	1,783	$51.85	$92,449	4,853
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	2,060	$51.00	$105,060	6,636
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	8,611	$52.72	$453,972	86,202
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	58,345	$51.97	$3,032,190	94,813
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	66,956	$51.00	$3,414,756	153,158
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	266	$52.73	$14,026	86,202
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	2,328	$51.85	$120,707	86,468
2024-12-02	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Exercise / conversion M	Common Stock	2,594	$51.00	$132,294	88,796
2024-07-16	Gravier Pierre	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	2,269	$34.02	$77,200	53,531
2024-05-22	ZELDIS JEROME B	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	20,000	$0.00	$0	0
2024-05-22	ZELDIS JEROME B	—	Open-market sell S	Common Stock	20,000	$38.24	$764,800	14,500
2024-05-22	ZELDIS JEROME B	—	Exercise / conversion M	Common Stock	20,000	$26.42	$528,400	34,500
2024-05-08	SOUTHWELL DAVID P	—	Equity grant / award G	Common Stock	1,650	$0.00	$0	12,850
2024-05-07	Golden Lee Scott	EVP & CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	175	$32.82	$5,744	59,813
2024-04-19	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	3,361	$24.89	$83,669	225,807
2024-04-17	Pauwels Eric	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	787	$25.14	$19,781	67,694
2024-04-02	Golden Lee Scott	EVP & CHIEF MEDICAL OFFICER	Open-market sell S	Common Stock	526	$28.37	$14,923	59,988
2024-02-15	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Equity grant / award A · derivative	Stock Option (Right to Buy)	35,000	$0.00	$0	35,000
2024-02-15	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Equity grant / award A	Common Stock	2,900	$0.00	$0	52,428
2024-02-15	Utter Christine Marie	SVP, CHIEF ACCOUNTING OFFICER	Equity grant / award A	Common Stock	14,000	$0.00	$0	49,528
2024-01-30	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	28	$27.25	$763	3,706
2024-01-30	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	618	$27.25	$16,841	61,202
2024-01-22	Jacobson Allan Steven	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$27.05	$270,500	0
2024-01-22	Jacobson Allan Steven	—	Open-market sell S	Common Stock	10,000	$27.38	$273,804	12,348
2024-01-22	Jacobson Allan Steven	—	Exercise / conversion M	Common Stock	10,000	$27.05	$270,500	22,348
2024-01-09	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	1,653	$29.01	$47,961	35,846
2024-01-08	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	1,188	$28.64	$34,025	37,499
2024-01-05	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	10,107	$27.15	$274,393	168,155
2023-12-28	Klein Matthew B.	CHIEF EXECUTIVE OFFICER	Equity grant / award A	Common Stock	75,000	$0.00	$0	177,961
2023-12-12	Gravier Pierre	CHIEF FINANCIAL OFFICER	Open-market buy P	Common Stock	7,700	$25.81	$198,736	33,700
2023-09-06	Young Alethia	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,666	$27.85	$129,948	7,334
2023-09-06	Young Alethia	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,000	$27.85	$194,950	0
2023-09-06	Young Alethia	—	Open-market sell S	Common Stock	4,666	$39.79	$185,672	9,067
2023-09-06	Young Alethia	—	Exercise / conversion M	Common Stock	4,666	$27.85	$129,948	13,733
2023-09-06	Young Alethia	—	Open-market sell S	Common Stock	7,000	$39.90	$279,300	9,067
2023-09-06	Young Alethia	—	Exercise / conversion M	Common Stock	7,000	$27.85	$194,950	16,067
2023-07-13	Gravier Pierre	CHIEF FINANCIAL OFFICER	Equity grant / award A · derivative	Stock Option (Right to Buy)	65,000	$0.00	$0	65,000
2023-07-13	Gravier Pierre	CHIEF FINANCIAL OFFICER	Equity grant / award A	Common Stock	26,000	$0.00	$0	26,000
2023-06-07	SCHMERTZLER MICHAEL	—	Open-market sell S	Common Stock	1,000	$44.86	$44,860	116,766
2023-06-06	Bell William F. Jr.	—	Equity grant / award A · derivative	Stock Option (Right to Buy)	5,834	$0.00	$0	5,834
2023-06-06	Bell William F. Jr.	—	Equity grant / award A · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	10,000
2023-06-06	Bell William F. Jr.	—	Equity grant / award A	Common Stock	2,333	$0.00	$0	6,333
2023-06-06	Bell William F. Jr.	—	Equity grant / award A	Common Stock	4,000	$0.00	$0	4,000
2023-05-23	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,402	$33.63	$47,149	8,650
2023-05-23	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,093	$33.02	$36,091	6,912
2023-05-23	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	157	$33.63	$5,280	837
2023-05-23	Reeve Emma	—	Open-market sell S	Common Stock	1,402	$59.54	$83,472	7,200
2023-05-23	Reeve Emma	—	Exercise / conversion M	Common Stock	1,402	$33.63	$47,149	8,602
2023-05-23	Reeve Emma	—	Open-market sell S	Common Stock	1,093	$59.53	$65,068	7,200
2023-05-23	Reeve Emma	—	Exercise / conversion M	Common Stock	1,093	$33.02	$36,091	8,293
2023-05-23	Reeve Emma	—	Open-market sell S	Common Stock	157	$59.52	$9,344	7,200
2023-05-23	Reeve Emma	—	Exercise / conversion M	Common Stock	157	$33.63	$5,280	7,357
2023-05-22	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	100	$59.66	$5,966	47,553
2023-05-22	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	1,913	$58.98	$112,825	47,653
2023-05-22	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,948	$33.63	$132,771	10,052
2023-05-22	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,995	$33.02	$98,895	8,005
2023-05-22	Reeve Emma	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	173	$33.63	$5,818	994
2023-05-22	Reeve Emma	—	Open-market sell S	Common Stock	3,948	$59.53	$235,030	7,200
2023-05-22	Reeve Emma	—	Exercise / conversion M	Common Stock	3,948	$33.63	$132,771	11,148
2023-05-22	Reeve Emma	—	Open-market sell S	Common Stock	2,995	$59.53	$178,303	7,200
2023-05-22	Reeve Emma	—	Exercise / conversion M	Common Stock	2,995	$33.02	$98,895	10,195
2023-05-22	Reeve Emma	—	Open-market sell S	Common Stock	173	$59.52	$10,298	7,200
2023-05-22	Reeve Emma	—	Exercise / conversion M	Common Stock	173	$33.63	$5,818	7,373
2023-05-19	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	6,403	$58.96	$377,491	49,566
2023-05-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	788	$58.71	$46,267	55,969
2023-05-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	7,248	$58.50	$424,008	56,757
2023-05-17	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	800	$58.52	$46,814	64,005
2023-05-11	Jacobson Allan Steven	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	23,000	$10.85	$249,550	0
2023-05-11	Jacobson Allan Steven	—	Open-market sell S	Common Stock	1,100	$56.99	$62,687	12,348
2023-05-11	Jacobson Allan Steven	—	Open-market sell S	Common Stock	2,860	$56.35	$161,169	13,448
2023-05-11	Jacobson Allan Steven	—	Open-market sell S	Common Stock	19,040	$54.78	$1,043,074	16,308
2023-05-11	Jacobson Allan Steven	—	Exercise / conversion M	Common Stock	23,000	$10.85	$249,550	35,348
2023-04-21	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	371	$33.02	$12,250	0
2023-04-21	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,321	$33.02	$142,679	0
2023-04-21	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	20	$55.64	$1,113	38,059
2023-04-21	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	351	$55.09	$19,337	38,079
2023-04-21	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M	Common Stock	371	$33.02	$12,250	38,430
2023-04-21	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	4,321	$55.05	$237,876	38,059
2023-04-21	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M	Common Stock	4,321	$33.02	$142,679	42,380
2023-04-18	Pauwels Eric	CHIEF BUSINESS OFFICER	Open-market sell S	Common Stock	732	$52.04	$38,096	64,805
2023-04-17	SOUTHWELL DAVID P	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	11,429	$18.01	$205,836	0
2023-04-17	SOUTHWELL DAVID P	—	Open-market sell S	Common Stock	5,188	$51.43	$266,840	10,500
2023-04-17	SOUTHWELL DAVID P	—	Open-market sell S	Common Stock	6,241	$50.69	$316,348	15,688
2023-04-17	SOUTHWELL DAVID P	—	Exercise / conversion M	Common Stock	11,429	$18.01	$205,836	21,929
2023-03-31	SOUTHWELL DAVID P	—	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,571	$18.01	$46,304	11,429
2023-03-31	SOUTHWELL DAVID P	—	Open-market sell S	Common Stock	2,571	$50.05	$128,672	10,500
2023-03-31	SOUTHWELL DAVID P	—	Exercise / conversion M	Common Stock	2,571	$18.01	$46,304	13,071
2023-03-29	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,688	$40.45	$189,630	0
2023-03-29	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	1,441	$47.78	$68,844	38,059
2023-03-29	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	3,247	$47.80	$155,200	39,500
2023-03-29	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M	Common Stock	4,688	$40.45	$189,630	42,747
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	9,729	$33.02	$321,252	371
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	16,929	$33.02	$558,996	4,321
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	300	$46.01	$13,803	38,059
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	4,954	$45.38	$224,833	38,359
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	4,475	$44.71	$200,058	43,313
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M	Common Stock	9,729	$33.02	$321,252	47,788
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	200	$46.01	$9,201	38,059
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	8,780	$45.42	$398,749	38,259
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	7,949	$44.72	$355,461	47,039
2023-03-27	Utter Christine Marie	SVP, FINANCE & CAO	Exercise / conversion M	Common Stock	16,929	$33.02	$558,996	54,988
2023-01-31	Utter Christine Marie	SVP, FINANCE & CAO	Open-market sell S	Common Stock	325	$45.63	$14,829	38,059
2023-01-24	Peltz Stuart Walter	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	284	$47.45	$13,476	55,204
2023-01-11	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	27	$44.36	$1,198	3,331
2023-01-11	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	383	$44.36	$16,990	64,579
2023-01-10	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	27	$42.93	$1,159	3,358
2023-01-10	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	473	$42.93	$20,307	64,962
2023-01-09	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	43	$41.66	$1,791	3,385
2023-01-09	Almstead Neil Gregory	CHIEF TECHNICAL OPS OFFICER	Open-market sell S	Common Stock	716	$41.66	$29,826	65,435
2023-01-05	Utter Christine Marie	SVP, FINANCE & CAO	Equity grant / award A · derivative	Stock Option (Right to Buy)	32,500	$0.00	$0	32,500
2023-01-05	Utter Christine Marie	SVP, FINANCE & CAO	Equity grant / award A	Common Stock	14,000	$0.00	$0	39,996
2022-10-18	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	289	$30.86	$8,919	61,923
2022-10-18	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10	$30.86	$309	62,212
2022-10-18	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	289	$55.04	$15,907	61,110
2022-10-18	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	289	$30.86	$8,919	61,399
2022-10-18	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	10	$55.45	$554	61,110
2022-10-18	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	10	$30.86	$309	61,120
2022-10-17	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,402	$30.86	$197,566	62,222
2022-10-17	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	200	$30.86	$6,172	68,624
2022-10-17	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	6,402	$55.00	$352,110	61,110
2022-10-17	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	6,402	$30.86	$197,566	67,512
2022-10-17	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	200	$55.00	$11,000	61,110
2022-10-17	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	200	$30.86	$6,172	61,310
2022-09-20	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	300	$30.86	$9,258	68,824
2022-09-20	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	876	$30.86	$27,033	69,124
2022-09-20	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	300	$55.00	$16,500	61,110
2022-09-20	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	300	$30.86	$9,258	61,410
2022-09-20	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	876	$55.00	$48,180	61,110
2022-09-20	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	876	$30.86	$27,033	61,986
2022-08-09	Okey Stephanie	—	Open-market sell S	Common Stock	2,296	$51.62	$118,522	1,867
2022-06-09	Young Alethia	—	Equity grant / award A · derivative	Stock Option (Right to Buy)	7,000	$0.00	$0	7,000
2022-06-09	Young Alethia	—	Equity grant / award A · derivative	Stock Option (Right to Buy)	12,000	$0.00	$0	12,000
2022-06-09	Young Alethia	—	Equity grant / award A	Common Stock	1,867	$0.00	$0	5,067
2022-06-09	Young Alethia	—	Equity grant / award A	Common Stock	3,200	$0.00	$0	3,200
2022-06-07	Peltz Stuart Walter	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	407	$26.83	$10,919	38,239
2022-04-19	Klein Matthew B.	CHIEF OPERATING OFFICER	Open-market sell S	Common Stock	897	$42.52	$38,136	56,564
2022-04-14	Peltz Stuart Walter	CHIEF EXECUTIVE OFFICER	Open-market sell S	Common Stock	82	$45.28	$3,713	38,646
2022-04-13	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,276	$11.23	$25,559	0
2022-04-13	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	2,276	$45.17	$102,811	61,110
2022-04-13	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	2,276	$11.23	$25,559	63,386
2022-04-05	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5	$11.23	$56	2,276
2022-04-05	Boulding Mark Elliott	EXEC. VP AND CLO	Open-market sell S	Common Stock	5	$45.00	$225	61,110
2022-04-05	Boulding Mark Elliott	EXEC. VP AND CLO	Exercise / conversion M	Common Stock	5	$11.23	$56	61,115
2022-03-31	Hill Emily Luisa	CHIEF FINANCIAL OFFICER	Open-market sell S	Common Stock	7,910	$37.78	$298,824	29,259
2022-02-10	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	15,653	$18.01	$281,911	0
2022-02-10	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,282	$11.23	$25,627	2,281
2022-02-10	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	15,653	$45.03	$704,808	61,110
2022-02-10	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	15,653	$18.01	$281,911	76,763
2022-02-10	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	2,282	$45.03	$102,752	61,110
2022-02-10	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	2,282	$11.23	$25,627	63,392
2022-02-02	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	707	$40.38	$28,549	25,405
2022-02-01	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	313	$40.00	$12,521	26,112
2022-01-25	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	330	$39.31	$12,974	39,010
2022-01-18	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$18.01	$180,100	0
2022-01-18	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	10,000	$44.00	$440,000	26,425
2022-01-18	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	10,000	$18.01	$180,100	36,425
2022-01-18	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	1,428	$43.50	$62,118	26,425
2022-01-07	Utter Christine Marie	SVP, Finance & CAO	Equity grant / award A · derivative	Stock Option (Right to Buy)	43,500	$0.00	$0	43,500
2022-01-07	Utter Christine Marie	SVP, Finance & CAO	Equity grant / award A	Common Stock	11,600	$0.00	$0	27,853
2022-01-07	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	747	$38.52	$28,778	16,253
2022-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	64	$41.16	$2,634	1,755
2021-09-02	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,363	$18.01	$60,568	15,653
2021-09-02	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	3,363	$45.01	$151,375	48,374
2021-09-02	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	3,363	$18.01	$60,568	51,737
2021-08-13	Okey Stephanie	Dir	Open-market sell S	Common Stock	1,650	$40.06	$66,094	963
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	244	$18.01	$4,394	19,016
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	227	$18.01	$4,088	19,260
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	410	$18.01	$7,384	19,487
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	548	$18.01	$9,869	19,897
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	244	$45.00	$10,980	48,374
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	244	$18.01	$4,394	48,618
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	227	$45.00	$10,215	48,374
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	227	$18.01	$4,088	48,601
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	410	$45.00	$18,451	48,374
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	410	$18.01	$7,384	48,784
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	548	$45.00	$24,660	48,374
2021-07-09	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	548	$18.01	$9,869	48,922
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,405	$18.01	$25,304	20,445
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,800	$18.01	$32,418	21,850
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,500	$18.01	$27,015	23,650
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	1,100	$18.01	$19,811	25,150
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,000	$11.23	$11,230	4,563
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	1,000	$11.23	$11,230	5,563
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,405	$45.23	$63,545	48,374
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	1,405	$18.01	$25,304	49,779
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,800	$45.20	$81,360	48,374
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	1,800	$18.01	$32,418	50,174
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,500	$45.22	$67,832	48,374
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	1,500	$18.01	$27,015	49,874
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,100	$45.21	$49,732	48,374
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	1,100	$18.01	$19,811	49,474
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,000	$45.25	$45,254	48,374
2021-07-08	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	1,000	$11.23	$11,230	49,374
2021-06-11	Smith Mary L.	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	5,834	$0.00	$0	5,834
2021-06-11	Smith Mary L.	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	10,000
2021-06-11	Smith Mary L.	Dir	Equity grant / award A	Common Stock	963	$0.00	$0	2,613
2021-06-11	Smith Mary L.	Dir	Equity grant / award A	Common Stock	1,650	$0.00	$0	1,650
2021-06-09	Svoronos Dawn	Dir	Open-market sell S	Common Stock	365	$41.88	$15,288	27,065
2021-04-19	Pauwels Eric	Chief Business Officer	Open-market sell S	Common Stock	786	$48.17	$37,860	35,701
2021-04-13	Peltz Stuart Walter	Chief Executive Officer	Equity grant / award A	Common Stock	1,400	$0.00	$0	16,481
2021-02-08	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,657	$33.02	$87,734	21,250
2021-02-08	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	2,657	$66.00	$175,362	16,509
2021-02-08	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	2,657	$33.02	$87,734	19,166
2021-02-02	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	652	$57.64	$37,581	16,509
2021-02-01	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	368	$56.96	$20,960	17,161
2021-01-25	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	44	$62.05	$2,730	1,847
2021-01-25	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	497	$63.25	$31,435	1,891
2021-01-15	Klein Matthew B.	Chief Development Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	4,300	$38.98	$167,614	86,314
2021-01-15	Klein Matthew B.	Chief Development Officer	Open-market sell S	Common Stock	4,300	$69.09	$297,078	19,309
2021-01-15	Klein Matthew B.	Chief Development Officer	Exercise / conversion M	Common Stock	4,300	$38.98	$167,614	23,609
2021-01-13	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,500	$18.01	$45,025	10,000
2021-01-13	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	788	$11.23	$8,849	0
2021-01-13	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	2,500	$66.57	$166,425	17,529
2021-01-13	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	2,500	$18.01	$45,025	20,029
2021-01-13	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	788	$66.57	$52,457	17,529
2021-01-13	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	788	$11.23	$8,849	18,317
2021-01-13	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	659	$66.57	$43,870	17,529
2021-01-08	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,300	$27.05	$35,165	0
2021-01-08	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	1,300	$69.00	$89,700	2,388
2021-01-08	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	1,300	$27.05	$35,165	3,688
2021-01-06	Hill Emily Luisa	Chief Financial Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	63,000	$0.00	$0	63,000
2021-01-06	Hill Emily Luisa	Chief Financial Officer	Equity grant / award A	Common Stock	10,800	$0.00	$0	24,122
2021-01-05	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	772	$62.37	$48,150	38,952
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	600	$10.85	$6,510	0
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	48,125	$18.01	$866,731	17,500
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	187	$18.01	$3,368	65,625
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	5,715	$11.23	$64,179	0
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	4,188	$18.01	$75,426	65,812
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,188	$11.23	$24,571	5,715
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,035	$11.23	$34,083	7,903
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	32,771	$27.05	$886,456	0
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	7,229	$27.05	$195,544	32,771
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	600	$60.65	$36,390	1,912
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	600	$10.85	$6,510	2,512
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	189	$61.24	$11,574	27,089
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	47,936	$60.58	$2,903,723	27,278
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	48,125	$18.01	$866,731	75,214
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	187	$60.61	$11,334	27,089
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	187	$18.01	$3,368	27,276
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	5,615	$60.56	$340,044	27,189
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	5,715	$11.23	$64,179	32,804
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	4,188	$60.59	$253,743	27,089
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	4,188	$18.01	$75,426	31,277
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	2,188	$60.54	$132,466	27,089
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	2,188	$11.23	$24,571	29,277
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	100	$61.24	$6,124	27,089
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	2,935	$60.56	$177,741	27,189
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	3,035	$11.23	$34,083	30,124
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	200	$61.24	$12,249	27,089
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	32,571	$60.58	$1,973,021	27,289
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	32,771	$27.05	$886,456	59,860
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	7,229	$60.59	$438,012	27,089
2021-01-04	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	7,229	$27.05	$195,544	34,318
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	115,937	$33.02	$3,828,240	149,063
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	169,781	$30.86	$5,239,442	5,219
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	7,938	$63.25	$502,047	56,085
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	30,060	$62.27	$1,871,776	64,023
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	77,939	$61.43	$4,787,793	94,083
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	115,937	$33.02	$3,828,240	172,022
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	8,212	$63.19	$518,924	56,085
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	38,779	$62.34	$2,417,560	64,297
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	122,790	$61.43	$7,543,358	103,076
2020-12-30	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	169,781	$30.86	$5,239,442	225,866
2020-12-15	Reeve Emma	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,028	$33.02	$33,945	11,000
2020-12-15	Reeve Emma	Dir	Exercise / conversion M	Common Stock	1,028	$33.02	$33,945	2,678
2020-12-14	Reeve Emma	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	972	$33.02	$32,095	12,028
2020-12-14	Reeve Emma	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	1,000	$33.02	$33,020	13,000
2020-12-14	Reeve Emma	Dir	Open-market sell S	Common Stock	972	$68.00	$66,096	1,650
2020-12-14	Reeve Emma	Dir	Exercise / conversion M	Common Stock	972	$33.02	$32,095	2,622
2020-12-14	Reeve Emma	Dir	Open-market sell S	Common Stock	1,000	$68.00	$68,000	1,650
2020-12-14	Reeve Emma	Dir	Exercise / conversion M	Common Stock	1,000	$33.02	$33,020	2,650
2020-12-08	Okey Stephanie	Dir	Open-market sell S	Common Stock	687	$62.52	$42,954	963
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	137,500	$18.01	$2,476,375	62,500
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	18,125	$11.23	$203,544	7,875
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	192,792	$27.05	$5,215,024	0
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	310	$65.70	$20,369	56,085
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	13,530	$64.61	$874,133	56,395
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	5,520	$63.65	$351,359	69,925
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	9,927	$62.41	$619,574	75,445
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	23,543	$61.68	$1,452,038	85,372
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	22,902	$60.66	$1,389,281	108,915
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	61,768	$59.56	$3,678,902	131,817
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	137,500	$18.01	$2,476,375	193,585
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	300	$65.19	$19,558	56,085
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	3,242	$64.36	$208,665	56,385
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	747	$63.01	$47,068	59,627
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	2,852	$61.90	$176,547	60,374
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	3,332	$60.84	$202,726	63,226
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	7,652	$59.58	$455,906	66,558
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	18,125	$11.23	$203,544	74,210
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	1,700	$65.78	$111,818	56,085
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	18,022	$64.62	$1,164,672	57,785
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	6,494	$63.67	$413,499	75,807
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	13,984	$62.44	$873,091	82,301
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	33,443	$61.68	$2,062,764	96,285
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	34,036	$60.64	$2,063,807	129,728
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	85,113	$59.56	$5,068,990	163,764
2020-12-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	192,792	$27.05	$5,215,024	248,877
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	8,421	$33.02	$278,061	18,529
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,065	$18.01	$127,241	13,399
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	2,362	$11.23	$26,525	2,363
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	7,560	$30.86	$233,302	0
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	2,505	$18.01	$45,115	20,464
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	1,575	$11.23	$17,687	4,725
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	500	$12.64	$6,320	375
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	3,440	$30.86	$106,158	7,560
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	4,900	$27.05	$132,545	0
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	8,421	$60.00	$505,260	12,178
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	8,421	$33.02	$278,061	20,599
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	7,065	$60.00	$423,900	12,178
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	7,065	$18.01	$127,241	19,243
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	2,362	$60.00	$141,720	12,178
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	2,362	$11.23	$26,525	14,540
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	7,560	$60.00	$453,600	12,178
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	7,560	$30.86	$233,302	19,738
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	2,505	$60.00	$150,300	12,178
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	2,505	$18.01	$45,115	14,683
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	1,575	$60.00	$94,500	12,178
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	1,575	$11.23	$17,687	13,753
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	500	$60.00	$30,000	12,178
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	500	$12.64	$6,320	12,678
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	3,440	$60.00	$206,400	12,178
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	3,440	$30.86	$106,158	15,618
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	4,900	$60.00	$294,000	12,178
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	4,900	$27.05	$132,545	17,078
2020-11-04	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	11,037	$60.00	$662,220	12,178
2020-11-03	Pauwels Eric	Chief Business Officer	Open-market sell S	Common Stock	6,194	$56.50	$349,961	27,647
2020-11-02	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	50,000	$10.85	$542,500	2,115
2020-11-02	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	11,813	$54.79	$647,282	56,085
2020-11-02	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	9,114	$53.86	$490,907	67,898
2020-11-02	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	29,073	$53.13	$1,544,765	77,012
2020-11-02	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	50,000	$10.85	$542,500	106,085
2020-10-16	Jacobson Allan Steven	Dir	Open-market sell S	Common Stock	5,000	$51.29	$256,450	3,498
2020-10-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	48,175	$11.23	$541,005	26,000
2020-10-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	22,929	$10.85	$248,780	10,694
2020-10-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	31,681	$53.62	$1,698,608	56,085
2020-10-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	16,494	$52.94	$873,126	87,766
2020-10-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	48,175	$11.23	$541,005	104,260
2020-10-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	11,786	$53.69	$632,814	56,085
2020-10-07	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	11,143	$53.01	$590,713	67,871
2020-10-07	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	22,929	$10.85	$248,780	79,014
2020-10-06	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	51,825	$11.23	$581,995	74,175
2020-10-06	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	22,511	$10.85	$244,244	33,623
2020-10-06	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	50,015	$10.85	$542,663	52,115
2020-10-06	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	51,825	$50.14	$2,598,350	56,085
2020-10-06	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	51,825	$11.23	$581,995	107,910
2020-10-06	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	22,511	$50.15	$1,128,882	56,085
2020-10-06	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	22,511	$10.85	$244,244	78,596
2020-10-06	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	50,015	$50.10	$2,505,852	56,085
2020-10-06	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	50,015	$10.85	$542,663	106,100
2020-10-05	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	54,560	$10.85	$591,976	56,134
2020-10-05	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	900	$10.85	$9,765	102,130
2020-10-05	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	54,560	$50.00	$2,728,000	56,085
2020-10-05	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	54,560	$10.85	$591,976	110,645
2020-10-05	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	900	$50.00	$45,000	56,085
2020-10-05	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	900	$10.85	$9,765	56,985
2020-07-15	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	50,000	$10.85	$542,500	103,030
2020-07-15	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	24,401	$55.93	$1,364,748	56,085
2020-07-15	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	25,599	$55.48	$1,420,233	80,486
2020-07-15	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	24,403	$55.94	$1,365,177	56,085
2020-07-15	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	25,597	$55.48	$1,419,994	80,488
2020-07-15	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	50,000	$10.85	$542,500	106,085
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	17,500	$18.01	$315,175	26,250
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	13,125	$11.23	$147,394	6,563
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	3,675	$55.24	$203,011	39,824
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	7,350	$55.23	$405,955	44,499
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,000	$54.20	$54,202	51,849
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	3,775	$55.26	$208,591	52,849
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	600	$54.20	$32,517	43,499
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	17,500	$18.01	$315,175	57,224
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	200	$55.73	$11,146	39,724
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	4,301	$55.23	$237,536	39,924
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	626	$54.18	$33,916	44,225
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	2,881	$55.24	$159,144	44,851
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	400	$55.74	$22,295	44,099
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	100	$55.73	$5,573	39,724
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	2,824	$55.22	$155,953	48,232
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	357	$54.11	$19,317	51,056
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	962	$55.31	$53,205	51,413
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	474	$54.70	$25,927	52,375
2020-07-07	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	13,125	$11.23	$147,394	52,849
2020-07-06	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	2,500	$18.01	$45,025	17,855
2020-07-06	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	788	$11.23	$8,849	1,575
2020-07-06	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	500	$54.40	$27,202	9,562
2020-07-06	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	2,000	$53.81	$107,614	10,062
2020-07-06	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	2,500	$18.01	$45,025	12,062
2020-07-06	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	788	$52.98	$41,748	9,562
2020-07-06	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	788	$11.23	$8,849	10,350
2020-06-29	Hill Emily Luisa	Chief Financial Officer	Open-market sell S	Common Stock	2,581	$52.50	$135,502	13,610
2020-06-11	Svoronos Dawn	Dir	Open-market sell S	Common Stock	364	$48.36	$17,603	26,286
2020-05-20	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	33,788	$10.85	$366,600	203,030
2020-05-20	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	33,788	$50.00	$1,689,400	56,085
2020-05-20	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	33,788	$10.85	$366,600	89,873
2020-05-18	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	6,284	$10.85	$68,181	236,818
2020-05-18	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	6,284	$50.12	$314,979	56,085
2020-05-18	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	6,284	$10.85	$68,181	62,369
2020-05-05	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	109,928	$10.85	$1,192,719	243,102
2020-05-05	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	1,985	$51.01	$101,253	56,085
2020-05-05	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	107,943	$50.33	$5,432,339	58,070
2020-05-05	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	109,928	$10.85	$1,192,719	166,013
2020-04-17	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	2,145	$18.01	$38,631	20,355
2020-04-17	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	2,145	$50.00	$107,250	9,304
2020-04-17	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	2,145	$18.01	$38,631	11,449
2020-04-16	Klein Matthew B.	Chief Development Officer	Equity grant / award A · derivative	Stock Option (Right To Buy)	50,000	$47.49	$2,374,500	50,000
2020-04-16	Klein Matthew B.	Chief Development Officer	Equity grant / award A	Common Stock	10,000	$0.00	$0	10,000
2020-04-03	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	787	$11.23	$8,838	2,363
2020-04-03	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	787	$44.31	$34,872	9,304
2020-04-03	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	787	$11.23	$8,838	10,091
2020-03-16	SCHMERTZLER MICHAEL	Dir	Open-market buy P	Common Stock	10,000	$32.48	$324,846	100,066
2020-02-10	Souza Marcio	Chief Operating Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	625	$12.92	$8,075	3,125
2020-02-10	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	625	$53.92	$33,700	6,744
2020-02-10	Souza Marcio	Chief Operating Officer	Exercise / conversion M	Common Stock	625	$12.92	$8,075	7,369
2020-02-06	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	3,102	$10.85	$33,657	0
2020-02-06	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	46,898	$10.85	$508,843	0
2020-02-06	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	4,040	$55.00	$222,200	1,912
2020-02-06	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	3,102	$55.00	$170,610	27,089
2020-02-06	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	3,102	$10.85	$33,657	30,191
2020-02-06	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	46,898	$55.00	$2,579,390	27,089
2020-02-06	Almstead Neil Gregory	Chief Technical Ops Officer	Exercise / conversion M	Common Stock	46,898	$10.85	$508,843	73,987
2020-02-05	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	405	$55.00	$22,275	5,952
2020-01-29	Okey Stephanie	Dir	Equity grant / award A · derivative	Stock Option (Right To Buy)	10,000	$0.00	$0	10,000
2020-01-29	Okey Stephanie	Dir	Equity grant / award A	Common Stock	1,650	$0.00	$0	1,650
2020-01-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	154	$53.25	$8,200	5,074
2020-01-07	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	7,500	$18.01	$135,075	22,500
2020-01-07	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	6,250	$13.10	$81,875	0
2020-01-07	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	7,500	$50.03	$375,232	5,224
2020-01-07	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	7,500	$18.01	$135,075	12,724
2020-01-07	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	6,250	$50.00	$312,500	5,224
2020-01-07	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	6,250	$13.10	$81,875	11,474
2020-01-06	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	86	$48.17	$4,142	5,228
2020-01-06	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	360	$48.17	$17,340	5,224
2020-01-03	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	788	$11.23	$8,849	3,150
2020-01-03	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	788	$47.42	$37,367	5,584
2020-01-03	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	788	$11.23	$8,849	6,372
2020-01-02	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	2,362	$11.23	$26,525	3,938
2020-01-02	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	2,362	$47.89	$113,111	5,584
2020-01-02	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	2,362	$11.23	$26,525	7,946
2019-12-30	Souza Marcio	Chief Operating Officer	Equity grant / award G	Common Stock	1,000	$0.00	$0	37,497
2019-12-23	Souza Marcio	Chief Operating Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	6,250	$12.92	$80,750	3,750
2019-12-23	Souza Marcio	Chief Operating Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	15,881	$11.23	$178,344	7,219
2019-12-23	Souza Marcio	Chief Operating Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	30,000	$18.01	$540,300	45,000
2019-12-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	6,250	$48.80	$305,000	5,038
2019-12-23	Souza Marcio	Chief Operating Officer	Exercise / conversion M	Common Stock	6,250	$12.92	$80,750	11,288
2019-12-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	18,668	$49.19	$918,279	38,221
2019-12-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	11,332	$48.43	$548,820	56,889
2019-12-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	7,004	$49.32	$345,430	38,221
2019-12-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	8,877	$48.58	$431,245	45,225
2019-12-23	Souza Marcio	Chief Operating Officer	Exercise / conversion M	Common Stock	15,881	$11.23	$178,344	54,102
2019-12-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	21,271	$49.14	$1,045,257	38,221
2019-12-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	8,729	$48.32	$421,794	59,492
2019-12-23	Souza Marcio	Chief Operating Officer	Exercise / conversion M	Common Stock	30,000	$18.01	$540,300	68,221
2019-12-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	14,814	$49.14	$727,975	38,221
2019-12-23	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	6,000	$48.32	$289,932	53,035
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	7,656	$18.01	$137,885	22,969
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	5,741	$11.23	$64,471	6,300
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	1,000	$12.64	$12,640	875
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	559	$11.23	$6,278	12,041
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	125	$12.64	$1,580	1,875
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	3,900	$10.85	$42,315	0
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	7,656	$50.00	$382,800	18,676
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	7,656	$18.01	$137,885	26,332
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	5,741	$50.00	$287,050	18,676
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	5,741	$11.23	$64,471	24,417
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	1,000	$50.00	$50,000	18,676
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	1,000	$12.64	$12,640	19,676
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	559	$50.00	$27,950	18,676
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	559	$11.23	$6,278	19,235
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	125	$50.00	$6,250	18,676
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	125	$12.64	$1,580	18,801
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	3,900	$50.00	$195,000	18,676
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Exercise / conversion M	Common Stock	3,900	$10.85	$42,315	22,576
2019-12-03	Peltz Stuart Walter	Chief Executive Officer	Open-market sell S	Common Stock	3,482	$50.00	$174,100	18,676
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	4,375	$18.01	$78,794	43,750
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	3,281	$11.23	$36,846	19,688
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,441	$45.34	$65,329	29,524
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	2,934	$44.45	$130,428	30,965
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,399	$45.31	$63,394	29,524
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	2,976	$44.46	$132,313	30,923
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	4,375	$18.01	$78,794	33,899
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,098	$45.34	$49,787	29,524
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	2,183	$44.46	$97,047	30,622
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	1,000	$45.34	$45,342	29,524
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Open-market sell S	Common Stock	2,281	$44.48	$101,457	30,524
2019-07-05	Boulding Mark Elliott	Exec. VP and CLO	Exercise / conversion M	Common Stock	3,281	$11.23	$36,846	32,805
2019-07-01	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	9,297	$18.01	$167,439	30,000
2019-07-01	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	641	$30.86	$19,781	10,310
2019-07-01	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	3,133	$0.00	$0	0
2019-07-01	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	9,297	$45.15	$419,750	4,937
2019-07-01	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	9,297	$18.01	$167,439	14,234
2019-07-01	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	641	$45.15	$28,941	4,937
2019-07-01	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	641	$30.86	$19,781	5,578
2019-07-01	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	3,133	$45.15	$141,452	4,937
2019-07-01	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	3,133	$27.05	$84,748	8,070
2019-06-28	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	703	$18.01	$12,661	39,297
2019-06-28	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	49	$30.86	$1,512	10,951
2019-06-28	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M · derivative	Stock Option (Right To Buy)	236	$27.05	$6,384	3,133
2019-06-28	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	703	$45.00	$31,635	4,937
2019-06-28	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	703	$18.01	$12,661	5,640
2019-06-28	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	49	$45.00	$2,205	4,937
2019-06-28	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	49	$30.86	$1,512	4,986
2019-06-28	Utter Christine Marie	SVP, Finance & CAO	Open-market sell S	Common Stock	236	$45.00	$10,620	4,937
2019-06-28	Utter Christine Marie	SVP, Finance & CAO	Exercise / conversion M	Common Stock	236	$27.05	$6,384	5,173
2019-06-03	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	5,490	$40.38	$221,686	58,664
2019-05-31	Hill Emily Luisa	Chief Financial Officer	Equity grant / award A · derivative	Stock Option (Right To Buy)	50,000	$40.10	$2,005,000	50,000
2019-03-05	Utter Christine Marie	Principal Financial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	6,300	$11.23	$70,749	6,300
2019-03-05	Utter Christine Marie	Principal Financial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	18,750	$13.10	$245,625	6,250
2019-03-05	Utter Christine Marie	Principal Financial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	1,150	$0.00	$0	0
2019-03-05	Utter Christine Marie	Principal Financial Officer	Open-market sell S	Common Stock	3,540	$35.17	$124,502	4,937
2019-03-05	Utter Christine Marie	Principal Financial Officer	Open-market sell S	Common Stock	2,760	$34.70	$95,772	8,477
2019-03-05	Utter Christine Marie	Principal Financial Officer	Exercise / conversion M	Common Stock	6,300	$11.23	$70,749	11,237
2019-03-05	Utter Christine Marie	Principal Financial Officer	Open-market sell S	Common Stock	8,821	$35.21	$310,587	4,937
2019-03-05	Utter Christine Marie	Principal Financial Officer	Open-market sell S	Common Stock	9,929	$34.75	$345,033	13,758
2019-03-05	Utter Christine Marie	Principal Financial Officer	Exercise / conversion M	Common Stock	18,750	$13.10	$245,625	23,687
2019-03-05	Utter Christine Marie	Principal Financial Officer	Open-market sell S	Common Stock	610	$35.17	$21,454	4,937
2019-03-05	Utter Christine Marie	Principal Financial Officer	Open-market sell S	Common Stock	540	$34.71	$18,743	5,547
2019-03-05	Utter Christine Marie	Principal Financial Officer	Exercise / conversion M	Common Stock	1,150	$10.85	$12,478	6,087
2019-03-05	Utter Christine Marie	Principal Financial Officer	Open-market sell S	Common Stock	1,000	$35.25	$35,250	4,937
2019-03-05	Utter Christine Marie	Principal Financial Officer	Open-market sell S	Common Stock	1,509	$34.78	$52,483	5,937
2019-01-25	SCHMERTZLER MICHAEL	Dir	Open-market buy P	Common Stock	66,225	$30.20	$1,999,995	1,386,594
2019-01-22	Utter Christine Marie	Principal Financial Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	10,100	$0.00	$0	10,100
2019-01-22	Utter Christine Marie	Principal Financial Officer	Equity grant / award A · derivative	Stock Option (Right to Buy)	42,500	$0.00	$0	42,500
2019-01-07	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	68	$34.75	$2,363	5,649
2019-01-07	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	55	$34.75	$1,911	5,717
2019-01-07	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	57	$34.75	$1,981	5,772
2019-01-07	Almstead Neil Gregory	Chief Technical Ops Officer	Open-market sell S	Common Stock	473	$34.75	$16,437	17,396
2018-12-14	Okey Stephanie	Dir	Equity grant / award A · derivative	Stock Option (Right To Buy)	1,167	$0.00	$0	1,167
2018-12-14	Okey Stephanie	Dir	Equity grant / award A · derivative	Stock Option (Right To Buy)	14,000	$0.00	$0	14,000
2018-06-19	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Exercise / conversion M · derivative	Stock Option (Right To Buy)	20,000	$10.85	$217,000	46,898
2018-06-19	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Open-market sell S	Common Stock	12,000	$48.46	$581,520	17,154
2018-06-19	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Open-market sell S	Common Stock	8,000	$48.09	$384,720	29,154
2018-06-19	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Exercise / conversion M	Common Stock	20,000	$10.85	$217,000	37,154
2018-06-01	Souza Marcio	Chief Operating Officer	Open-market sell S	Common Stock	5,161	$34.65	$178,829	63,071
2018-01-05	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Open-market sell S	Common Stock	82	$18.03	$1,478	5,125
2018-01-05	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Open-market sell S	Common Stock	621	$18.03	$11,197	17,154
2018-01-03	STEELE GLENN JR MD PHD	Dir	Equity grant / award A · derivative	Stock Option (Right To Buy)	14,000	$0.00	$0	14,000
2017-06-02	Utter Christine Marie	Principal Financial Officer	Equity grant / award A · derivative	Stock Option (Right To Buy)	25,000	$0.00	$0	25,000
2017-05-31	Souza Marcio	Chief Operating Officer	Equity grant / award A · derivative	Stock Option (Right To Buy)	30,000	$12.53	$375,900	30,000
2017-05-31	Souza Marcio	Chief Operating Officer	Equity grant / award A	Common Stock	30,000	$0.00	$0	36,457
2017-05-24	Rothera Mark	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	2,000	$0.00	$0	6,125
2017-05-24	Rothera Mark	Chief Commercial Officer	Exercise / conversion M	Common Stock	2,000	$10.85	$21,700	33,739
2017-05-23	Svoronos Dawn	Dir	Open-market buy P	Common Stock	25,000	$13.49	$337,230	25,000
2017-05-09	Kovacs Shane William Charles	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	10,000	$0.00	$0	45,625
2017-05-09	Kovacs Shane William Charles	Chief Financial Officer	Exercise / conversion M	Common Stock	10,000	$10.85	$108,500	37,850
2017-04-28	Complete Pharma Holdings II, LLC	10%	Other disposed transaction J	Common Stock	6,683,598	$0.00	$0	0
2017-03-15	Rothera Mark	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	2,966	$0.00	$0	69,227
2017-03-15	Rothera Mark	Chief Commercial Officer	Exercise / conversion M	Common Stock	2,966	$10.85	$32,181	31,739
2017-02-16	Rothera Mark	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	3,125	$0.00	$0	72,193
2017-02-16	Rothera Mark	Chief Commercial Officer	Exercise / conversion M	Common Stock	3,125	$10.85	$33,906	28,773
2017-01-17	Rothera Mark	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	3,125	$0.00	$0	75,318
2017-01-17	Rothera Mark	Chief Commercial Officer	Exercise / conversion M	Common Stock	3,125	$10.85	$33,906	25,648
2017-01-05	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Open-market sell S	Common Stock	78	$11.82	$922	2,687
2017-01-03	SOUTHWELL DAVID P	Dir	Equity grant / award A · derivative	Stock Option (Right To Buy)	12,000	$0.00	$0	12,000
2016-11-14	Rothera Mark	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	1,941	$0.00	$0	78,443
2016-11-14	Rothera Mark	Chief Commercial Officer	Exercise / conversion M	Common Stock	1,941	$10.85	$21,060	11,216
2016-10-10	Rothera Mark	Chief Commercial Officer	Exercise / conversion M · derivative	Stock Option (Right To Buy)	1,950	$0.00	$0	80,384
2016-10-10	Rothera Mark	Chief Commercial Officer	Exercise / conversion M	Common Stock	1,950	$10.85	$21,158	9,275
2016-09-27	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Exercise / conversion M · derivative	Stock Option (Right to Buy)	6,586	$10.85	$71,458	3,102
2016-09-27	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Exercise / conversion M · derivative	Stock Option (Right to Buy)	3,414	$10.85	$37,042	66,898
2016-09-27	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Exercise / conversion M	Common Stock	6,586	$10.85	$71,458	10,000
2016-09-27	Almstead Neil Gregory	EVP Research Pharma Ops & Tech	Exercise / conversion M	Common Stock	3,414	$10.85	$37,042	3,414
2016-09-26	Kovacs Shane William Charles	Chief Financial Officer	Exercise / conversion M · derivative	Stock Option (Right to Buy)	10,000	$0.00	$0	55,625
2016-09-26	Kovacs Shane William Charles	Chief Financial Officer	Exercise / conversion M	Common Stock	10,000	$10.85	$108,500	18,850
2016-09-23	SCHMERTZLER MICHAEL	Dir	Exercise / conversion M · derivative	Stock Option (Right to Buy)	60,000	$0.00	$0	0
2016-09-23	SCHMERTZLER MICHAEL	Dir	Exercise / conversion M	Common Stock	60,000	$10.85	$651,000	86,766
2016-06-10	Svoronos Dawn	Dir	Equity grant / award A · derivative	Stock Option (Right to Buy)	20,000	$0.00	$0	20,000

Regulatory Activity

Last 12 months to 2025-04-29

Insider Filings (Forms 3/4/5) — 12 months

Material Event Filings (8-K) — 12 months

8-K Material Event Filing Activity

Monthly count

Insider Trading Activity (Forms 3/4/5)

Monthly count